Affinity Data by PubMed id=17988109

PubMed code 17988109

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50116067 ((Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50226485 ((R)-3-(3-fluoro-4-(tetrahydro-2H-pyran-4-yl)phenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50226479 ((R)-3-(3,5-difluoro-4-morpholinophenyl)-2-oxooxazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50226484 ((5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50226480 ((R)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.46E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50226481 ((5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.93E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50226482 ((5R)-3-[3,5-difluoro-4-(1-oxidotetrahydro-2H-thiop...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.55E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50226483 ((5R)-3-[3-fluoro-4-(1-oxidotetrahydro-2H-thiopyran...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human liver microsome CYP2D6				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50226483 ((5R)-3-[3-fluoro-4-(1-oxidotetrahydro-2H-thiopyran...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human liver microsome CYP1A2				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50226483 ((5R)-3-[3-fluoro-4-(1-oxidotetrahydro-2H-thiopyran...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human liver microsome CYP2C9				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50226483 ((5R)-3-[3-fluoro-4-(1-oxidotetrahydro-2H-thiopyran...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human liver microsome CYP2C19				J Med Chem 50: 5886-9 (2007) Article DOI: 10.1021/jm070708p BindingDB Entry DOI: 10.7270/Q22J6BM7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%