Found 29 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375355
(CHEMBL260861)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375360
(CHEMBL261188)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4cccnc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C26H29N7O4/c1-36-19-9-17(10-20(11-19)37-2)30-25-23(24(27)35)26-31-21(16-5-6-16)12-22(33(26)32-25)29-18(14-34)8-15-4-3-7-28-13-15/h3-4,7,9-13,16,18,29,34H,5-6,8,14H2,1-2H3,(H2,27,35)(H,30,32)/t18-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375361
(CHEMBL260157)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4c[nH]c5ccccc45)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C29H31N7O4/c1-39-20-10-18(11-21(12-20)40-2)33-28-26(27(30)38)29-34-24(16-7-8-16)13-25(36(29)35-28)32-19(15-37)9-17-14-31-23-6-4-3-5-22(17)23/h3-6,10-14,16,19,31-32,37H,7-9,15H2,1-2H3,(H2,30,38)(H,33,35)/t19-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50375355
(CHEMBL260861)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of Lck |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375366
(CHEMBL406418)Show SMILES COc1cc(Nc2nn3c(N[C@@H](CO)C(C)C)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C23H30N6O4/c1-12(2)18(11-30)26-19-10-17(13-5-6-13)27-23-20(21(24)31)22(28-29(19)23)25-14-7-15(32-3)9-16(8-14)33-4/h7-10,12-13,18,26,30H,5-6,11H2,1-4H3,(H2,24,31)(H,25,28)/t18-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375364
(CHEMBL261743)Show SMILES COc1cc(Nc2nn3c(cc(nc3c2C(N)=O)C2CC2)N2CCC[C@@H]2CO)cc(OC)c1 Show InChI InChI=1S/C23H28N6O4/c1-32-16-8-14(9-17(10-16)33-2)25-22-20(21(24)31)23-26-18(13-5-6-13)11-19(29(23)27-22)28-7-3-4-15(28)12-30/h8-11,13,15,30H,3-7,12H2,1-2H3,(H2,24,31)(H,25,27)/t15-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375362
(CHEMBL260860)Show SMILES COc1cc(Nc2nn3c(N[C@@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375363
(CHEMBL261744)Show SMILES COc1cc(Nc2nn3c(cc(nc3c2C(N)=O)C2CC2)N2CCC[C@H]2CO)cc(OC)c1 Show InChI InChI=1S/C23H28N6O4/c1-32-16-8-14(9-17(10-16)33-2)25-22-20(21(24)31)23-26-18(13-5-6-13)11-19(29(23)27-22)28-7-3-4-15(28)12-30/h8-11,13,15,30H,3-7,12H2,1-2H3,(H2,24,31)(H,25,27)/t15-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375367
(CHEMBL405893)Show SMILES COc1cc(Nc2nn3c(N[C@@H](CO)C(C)C)cc(nc3c2C(N)=O)C(C)C)cc(OC)c1 Show InChI InChI=1S/C23H32N6O4/c1-12(2)17-10-19(26-18(11-30)13(3)4)29-23(27-17)20(21(24)31)22(28-29)25-14-7-15(32-5)9-16(8-14)33-6/h7-10,12-13,18,26,30H,11H2,1-6H3,(H2,24,31)(H,25,28)/t18-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375368
(CHEMBL259200)Show SMILES COc1cc(Nc2nn3c(N[C@@H](CO)C(C)C)cc(nc3c2C(N)=O)-c2ccccc2)cc(OC)c1 Show InChI InChI=1S/C26H30N6O4/c1-15(2)21(14-33)29-22-13-20(16-8-6-5-7-9-16)30-26-23(24(27)34)25(31-32(22)26)28-17-10-18(35-3)12-19(11-17)36-4/h5-13,15,21,29,33H,14H2,1-4H3,(H2,27,34)(H,28,31)/t21-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375365
(CHEMBL261450)Show InChI InChI=1S/C16H16N6O/c17-12-8-11(9-6-7-9)20-16-13(14(18)23)15(21-22(12)16)19-10-4-2-1-3-5-10/h1-5,8-9H,6-7,17H2,(H2,18,23)(H,19,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375355
(CHEMBL260861)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc in COS7 cells by ELISA |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375360
(CHEMBL261188)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4cccnc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C26H29N7O4/c1-36-19-9-17(10-20(11-19)37-2)30-25-23(24(27)35)26-31-21(16-5-6-16)12-22(33(26)32-25)29-18(14-34)8-15-4-3-7-28-13-15/h3-4,7,9-13,16,18,29,34H,5-6,8,14H2,1-2H3,(H2,27,35)(H,30,32)/t18-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc in COS7 cells by ELISA |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375366
(CHEMBL406418)Show SMILES COc1cc(Nc2nn3c(N[C@@H](CO)C(C)C)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C23H30N6O4/c1-12(2)18(11-30)26-19-10-17(13-5-6-13)27-23-20(21(24)31)22(28-29(19)23)25-14-7-15(32-3)9-16(8-14)33-4/h7-10,12-13,18,26,30H,5-6,11H2,1-4H3,(H2,24,31)(H,25,28)/t18-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc in COS7 cells by ELISA |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375356
(CHEMBL260114)Show SMILES COc1cc(Nc2nn3c(NCC(C)(C)N)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C20H27N7O3/c1-11-6-15(23-10-20(2,3)22)27-19(24-11)16(17(21)28)18(26-27)25-12-7-13(29-4)9-14(8-12)30-5/h6-9,23H,10,22H2,1-5H3,(H2,21,28)(H,25,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375358
(CHEMBL258677)Show SMILES COc1cc(Nc2nn3c(NC[C@@H](C)N)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C19H25N7O3/c1-10(20)9-22-15-5-11(2)23-19-16(17(21)27)18(25-26(15)19)24-12-6-13(28-3)8-14(7-12)29-4/h5-8,10,22H,9,20H2,1-4H3,(H2,21,27)(H,24,25)/t10-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 408 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375369
(CHEMBL260024)Show SMILES COc1cc(Nc2nn3c(N[C@@H](CO)C(C)C)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C21H28N6O4/c1-11(2)16(10-28)25-17-6-12(3)23-21-18(19(22)29)20(26-27(17)21)24-13-7-14(30-4)9-15(8-13)31-5/h6-9,11,16,25,28H,10H2,1-5H3,(H2,22,29)(H,24,26)/t16-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 432 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375361
(CHEMBL260157)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4c[nH]c5ccccc45)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C29H31N7O4/c1-39-20-10-18(11-21(12-20)40-2)33-28-26(27(30)38)29-34-24(16-7-8-16)13-25(36(29)35-28)32-19(15-37)9-17-14-31-23-6-4-3-5-22(17)23/h3-6,10-14,16,19,31-32,37H,7-9,15H2,1-2H3,(H2,30,38)(H,33,35)/t19-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc in COS7 cells by ELISA |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375356
(CHEMBL260114)Show SMILES COc1cc(Nc2nn3c(NCC(C)(C)N)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C20H27N7O3/c1-11-6-15(23-10-20(2,3)22)27-19(24-11)16(17(21)28)18(26-27)25-12-7-13(29-4)9-14(8-12)30-5/h6-9,23H,10,22H2,1-5H3,(H2,21,28)(H,25,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc in COS7 cells by ELISA |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375370
(CHEMBL410296)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)C(C)C)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C21H28N6O4/c1-11(2)16(10-28)25-17-6-12(3)23-21-18(19(22)29)20(26-27(17)21)24-13-7-14(30-4)9-15(8-13)31-5/h6-9,11,16,25,28H,10H2,1-5H3,(H2,22,29)(H,24,26)/t16-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50375355
(CHEMBL260861)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of EGFR |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375357
(CHEMBL412139)Show SMILES COc1cc(Nc2nn3c(NC[C@H](C)N)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C19H25N7O3/c1-10(20)9-22-15-5-11(2)23-19-16(17(21)27)18(25-26(15)19)24-12-6-13(28-3)8-14(7-12)29-4/h5-8,10,22H,9,20H2,1-4H3,(H2,21,27)(H,24,25)/t10-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375371
(CHEMBL412273)Show SMILES COc1cc(Nc2nn3c(N[C@@H](C)CO)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C19H24N6O4/c1-10-5-15(21-11(2)9-26)25-19(22-10)16(17(20)27)18(24-25)23-12-6-13(28-3)8-14(7-12)29-4/h5-8,11,21,26H,9H2,1-4H3,(H2,20,27)(H,23,24)/t11-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375359
(CHEMBL427741)Show SMILES COc1cc(Nc2nn3c(NC[C@@H](C)O)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C19H24N6O4/c1-10-5-15(21-9-11(2)26)25-19(22-10)16(17(20)27)18(24-25)23-12-6-13(28-3)8-14(7-12)29-4/h5-8,11,21,26H,9H2,1-4H3,(H2,20,27)(H,23,24)/t11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50375372
(CHEMBL259627)Show SMILES COc1cc(Nc2nn3c(NC[C@H](C)O)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C19H24N6O4/c1-10-5-15(21-9-11(2)26)25-19(22-10)16(17(20)27)18(24-25)23-12-6-13(28-3)8-14(7-12)29-4/h5-8,11,21,26H,9H2,1-4H3,(H2,20,27)(H,23,24)/t11-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human cSrc |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Protein kinase C beta type
(Homo sapiens (Human)) | BDBM50375355
(CHEMBL260861)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of PKCbeta |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase SYK
(Homo sapiens (Human)) | BDBM50375355
(CHEMBL260861)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of Syk |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human)) | BDBM50375355
(CHEMBL260861)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of ZAP |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50375355
(CHEMBL260861)Show SMILES COc1cc(Nc2nn3c(N[C@H](CO)Cc4ccccc4)cc(nc3c2C(N)=O)C2CC2)cc(OC)c1 Show InChI InChI=1S/C27H30N6O4/c1-36-20-11-18(12-21(13-20)37-2)30-26-24(25(28)35)27-31-22(17-8-9-17)14-23(33(27)32-26)29-19(15-34)10-16-6-4-3-5-7-16/h3-7,11-14,17,19,29,34H,8-10,15H2,1-2H3,(H2,28,35)(H,30,32)/t19-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Ltd
Curated by ChEMBL
| Assay Description
Inhibition of KDR |
Bioorg Med Chem 16: 909-21 (2008)
Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01 |
More data for this
Ligand-Target Pair | |
Search and Browse
