Affinity Data by PubMed id=18022559

PubMed code 18022559

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM7401 ((2 Z,3 E)-6-Bromoindirubin-3 -oxime \| (3E)-6-bromo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.5	30
University of Munich					Assay Description PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...				Chem Biol 14: 1207-14 (2007) Article DOI: 10.1016/j.chembiol.2007.10.010 BindingDB Entry DOI: 10.7270/Q2668BN7
University of Munich					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM7393 (3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...) Show SMILES O=Nc1c([nH]c2ccccc12)C1C(=O)Nc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	30
University of Munich					Assay Description PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...				Chem Biol 14: 1207-14 (2007) Article DOI: 10.1016/j.chembiol.2007.10.010 BindingDB Entry DOI: 10.7270/Q2668BN7
University of Munich					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50218894 (7-bromoindirubin-3-oxime \| 7BIO \| CHEMBL1092509) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	30
University of Munich					Assay Description PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...				Chem Biol 14: 1207-14 (2007) Article DOI: 10.1016/j.chembiol.2007.10.010 BindingDB Entry DOI: 10.7270/Q2668BN7
University of Munich					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM81296 (5BIO) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	30
University of Munich					Assay Description PDK1 protein kinase was expressed in Sf9 insect cells as human recombinant GST-fusion protein by means of the baculovirus expression systems. Protei...				Chem Biol 14: 1207-14 (2007) Article DOI: 10.1016/j.chembiol.2007.10.010 BindingDB Entry DOI: 10.7270/Q2668BN7
University of Munich					More data for this Ligand-Target Pair

* indicates data uncertainty>20%