Found 7 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glutamate carboxypeptidase 2
(Homo sapiens (Human)) | BDBM50372201
(CHEMBL270610)Show SMILES CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OCCCOP([O-])(=O)N[C@@H](CCC([O-])=O)C([O-])=O Show InChI InChI=1S/C35H62NO8P/c1-23(2)8-6-9-24(3)28-12-13-29-27-11-10-25-22-26(16-18-34(25,4)30(27)17-19-35(28,29)5)43-20-7-21-44-45(41,42)36-31(33(39)40)14-15-32(37)38/h23-31H,6-22H2,1-5H3,(H,37,38)(H,39,40)(H2,36,41,42)/p-3/t24-,25?,26+,27+,28-,29+,30+,31+,34+,35-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington State University
Curated by ChEMBL
| Assay Description
Inhibition of human PSMA |
Bioorg Med Chem Lett 18: 281-4 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.096
BindingDB Entry DOI: 10.7270/Q2N29XS3 |
More data for this
Ligand-Target Pair | |
Glutamate carboxypeptidase 2
(Homo sapiens (Human)) | BDBM50372204
(CHEMBL402223)Show SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(OCCCOP([O-])(=O)N[C@@H](CCC([O-])=O)C([O-])=O)ccc34)[C@@H]1CCC2=O Show InChI InChI=1S/C26H36NO9P/c1-26-12-11-19-18-6-4-17(15-16(18)3-5-20(19)21(26)7-9-23(26)28)35-13-2-14-36-37(33,34)27-22(25(31)32)8-10-24(29)30/h4,6,15,19-22H,2-3,5,7-14H2,1H3,(H,29,30)(H,31,32)(H2,27,33,34)/p-3/t19-,20-,21+,22+,26+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington State University
Curated by ChEMBL
| Assay Description
Inhibition of human PSMA |
Bioorg Med Chem Lett 18: 281-4 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.096
BindingDB Entry DOI: 10.7270/Q2N29XS3 |
More data for this
Ligand-Target Pair | |
Glutamate carboxypeptidase 2
(Homo sapiens (Human)) | BDBM50222545
(CHEMBL394011 | tripotassium (2S)-2-{[(4-phenylbuto...)Show SMILES [O-]C(=O)CC[C@H](NP([O-])(=O)OCCCCc1ccccc1)C([O-])=O Show InChI InChI=1S/C15H22NO7P/c17-14(18)10-9-13(15(19)20)16-24(21,22)23-11-5-4-8-12-6-2-1-3-7-12/h1-3,6-7,13H,4-5,8-11H2,(H,17,18)(H,19,20)(H2,16,21,22)/p-3/t13-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington State University
Curated by ChEMBL
| Assay Description
Inhibition of human PSMA |
Bioorg Med Chem Lett 18: 281-4 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.096
BindingDB Entry DOI: 10.7270/Q2N29XS3 |
More data for this
Ligand-Target Pair | |
Glutamate carboxypeptidase 2
(Homo sapiens (Human)) | BDBM50372203
(CHEMBL270594)Show SMILES CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OP([O-])(=O)N[C@@H](CCC([O-])=O)C([O-])=O Show InChI InChI=1S/C32H56NO7P/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(15-17-31(22,4)27(24)16-18-32(25,26)5)40-41(38,39)33-28(30(36)37)13-14-29(34)35/h20-28H,6-19H2,1-5H3,(H,34,35)(H,36,37)(H2,33,38,39)/p-3/t21-,22?,23+,24+,25-,26+,27+,28+,31+,32-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 435 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington State University
Curated by ChEMBL
| Assay Description
Inhibition of human PSMA |
Bioorg Med Chem Lett 18: 281-4 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.096
BindingDB Entry DOI: 10.7270/Q2N29XS3 |
More data for this
Ligand-Target Pair | |
Glutamate carboxypeptidase 2
(Homo sapiens (Human)) | BDBM50372205
(CHEMBL270824)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](CC[C@]34C)OCCCOP([O-])(=O)N[C@@H](CCC([O-])=O)C([O-])=O)[C@@H]1CCC2=O Show InChI InChI=1S/C27H44NO9P/c1-26-12-10-18(36-14-3-15-37-38(34,35)28-22(25(32)33)7-9-24(30)31)16-17(26)4-5-19-20-6-8-23(29)27(20,2)13-11-21(19)26/h17-22H,3-16H2,1-2H3,(H,30,31)(H,32,33)(H2,28,34,35)/p-3/t17-,18-,19-,20-,21-,22-,26-,27-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 438 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington State University
Curated by ChEMBL
| Assay Description
Inhibition of human PSMA |
Bioorg Med Chem Lett 18: 281-4 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.096
BindingDB Entry DOI: 10.7270/Q2N29XS3 |
More data for this
Ligand-Target Pair | |
Glutamate carboxypeptidase 2
(Homo sapiens (Human)) | BDBM50372202
(CHEMBL437209)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](CC[C@]34C)OP([O-])(=O)N[C@@H](CCC([O-])=O)C([O-])=O)[C@@H]1CCC2=O Show InChI InChI=1S/C24H38NO8P/c1-23-11-9-15(33-34(31,32)25-19(22(29)30)6-8-21(27)28)13-14(23)3-4-16-17-5-7-20(26)24(17,2)12-10-18(16)23/h14-19H,3-13H2,1-2H3,(H,27,28)(H,29,30)(H2,25,31,32)/p-3/t14-,15-,16-,17-,18-,19-,23-,24-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 569 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington State University
Curated by ChEMBL
| Assay Description
Inhibition of human PSMA |
Bioorg Med Chem Lett 18: 281-4 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.096
BindingDB Entry DOI: 10.7270/Q2N29XS3 |
More data for this
Ligand-Target Pair | |
Glutamate carboxypeptidase 2
(Homo sapiens (Human)) | BDBM50372206
(CHEMBL402033)Show SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(OC(=O)c5ccccc5)ccc34)[C@@H]1CC[C@@H]2OCCCOP([O-])(=O)N[C@@H](CCC([O-])=O)C([O-])=O Show InChI InChI=1S/C33H42NO10P/c1-33-17-16-25-24-11-9-23(44-32(39)21-6-3-2-4-7-21)20-22(24)8-10-26(25)27(33)12-14-29(33)42-18-5-19-43-45(40,41)34-28(31(37)38)13-15-30(35)36/h2-4,6-7,9,11,20,25-29H,5,8,10,12-19H2,1H3,(H,35,36)(H,37,38)(H2,34,40,41)/p-3/t25-,26-,27+,28+,29+,33+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 572 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington State University
Curated by ChEMBL
| Assay Description
Inhibition of human PSMA |
Bioorg Med Chem Lett 18: 281-4 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.096
BindingDB Entry DOI: 10.7270/Q2N29XS3 |
More data for this
Ligand-Target Pair | |
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