Affinity Data by PubMed id=18047262

PubMed code 18047262

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228368 (1,2-dihydro-2-oxoquinazoline-4-carboxy-(4-methoxyp...) Show SMILES COc1ccc(NC(=O)c2[nH]c(=O)nc3ccccc23)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228372 (2-acetylaminoquinazoline-4-carboxyanilide \| CHEMBL...) Show SMILES CC(=O)Nc1nc(C(=O)Nc2ccccc2)c2ccccc2n1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228373 (1,2-dihydro-2-oxoquinazoline-4-carboxy-(4-methylph...) Show SMILES Cc1ccc(NC(=O)c2[nH]c(=O)nc3ccccc23)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228365 (1,2-dihydro-2-oxoquinazoline-4-carboxy-(4-bromophe...) Show SMILES Brc1ccc(NC(=O)c2[nH]c(=O)nc3ccccc23)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228374 (1,2-dihydro-2-oxoquinazoline-4-carboxyanilide \| CH...) Show SMILES O=C(Nc1ccccc1)c1[nH]c(=O)nc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228367 (2-aminoquinazoline-4-carboxy-(4-methoxyphenyl)amid...) Show SMILES COc1ccc(NC(=O)c2nc(N)nc3ccccc23)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228371 (2-aminoquinazoline-4-carboxy-(4-methylphenyl)amide...) Show SMILES Cc1ccc(NC(=O)c2nc(N)nc3ccccc23)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228369 (2-benzoylaminoquinazoline-4-carboxyanilide \| CHEMB...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228370 (2-aminoquinazoline-4-carboxyanilide \| CHEMBL238091) Show SMILES Nc1nc(C(=O)Nc2ccccc2)c2ccccc2n1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228366 (2-aminoquinazoline-4-carboxy-(4-bromophenyl)amide ...) Show SMILES Nc1nc(C(=O)Nc2ccc(Br)cc2)c2ccccc2n1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228368 (1,2-dihydro-2-oxoquinazoline-4-carboxy-(4-methoxyp...) Show SMILES COc1ccc(NC(=O)c2[nH]c(=O)nc3ccccc23)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Activity at human adenosine A3 receptor expressed in CHO cells assessed as antagonism of Cl-IB-MECA-inhibited cAMP production				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228372 (2-acetylaminoquinazoline-4-carboxyanilide \| CHEMBL...) Show SMILES CC(=O)Nc1nc(C(=O)Nc2ccccc2)c2ccccc2n1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Activity at human adenosine A3 receptor expressed in CHO cells assessed as antagonism of Cl-IB-MECA-inhibited cAMP production				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50228374 (1,2-dihydro-2-oxoquinazoline-4-carboxyanilide \| CH...) Show SMILES O=C(Nc1ccccc1)c1[nH]c(=O)nc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
Università di Padova Curated by ChEMBL					Assay Description Activity at human adenosine A3 receptor expressed in CHO cells assessed as antagonism of Cl-IB-MECA-inhibited cAMP production				J Med Chem 50: 6596-606 (2007) Article DOI: 10.1021/jm070852a BindingDB Entry DOI: 10.7270/Q2KD1XPJ
Università di Padova Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%