Affinity Data by PubMed id=18215519

PubMed code 18215519

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50374521 (CHEMBL272369) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from human CCR2 expressed in human monocytes				Bioorg Med Chem Lett 18: 1374-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.016 BindingDB Entry DOI: 10.7270/Q2R2127G
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50374523 (CHEMBL402532) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 assessed as inhibition of MCP1-induced monocyte chemotaxis				Bioorg Med Chem Lett 18: 1374-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.016 BindingDB Entry DOI: 10.7270/Q2R2127G
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50374523 (CHEMBL402532) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from human CCR2 expressed in human monocytes				Bioorg Med Chem Lett 18: 1374-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.016 BindingDB Entry DOI: 10.7270/Q2R2127G
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50374522 (CHEMBL401890) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from human CCR2 expressed in human monocytes				Bioorg Med Chem Lett 18: 1374-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.016 BindingDB Entry DOI: 10.7270/Q2R2127G
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%