Affinity Data by PubMed id=18243713

PubMed code 18243713

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50151869 (4-(3-(ethyl(3-(propylsulfinyl)propyl)amino)-2-hydr...) Show SMILES CCCS(=O)CCCN(CC)CC(O)COc1ccc(cc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel				Bioorg Med Chem 16: 4107-19 (2008) Article DOI: 10.1016/j.bmc.2008.01.017 BindingDB Entry DOI: 10.7270/Q23T9J4N
University of Vienna Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50251141 (5-chloro-1-(4-fluorophenyl)-N,N-dimethyl-1H-indol-...) Show SMILES CN(C)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel				Bioorg Med Chem 16: 4107-19 (2008) Article DOI: 10.1016/j.bmc.2008.01.017 BindingDB Entry DOI: 10.7270/Q23T9J4N
University of Vienna Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel				Bioorg Med Chem 16: 4107-19 (2008) Article DOI: 10.1016/j.bmc.2008.01.017 BindingDB Entry DOI: 10.7270/Q23T9J4N
University of Vienna Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM87351 (Amsacrine hydrochloride \| CHEMBL43 \| MLS002153376 ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel				Bioorg Med Chem 16: 4107-19 (2008) Article DOI: 10.1016/j.bmc.2008.01.017 BindingDB Entry DOI: 10.7270/Q23T9J4N
University of Vienna Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50241365 ((R)-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel				Bioorg Med Chem 16: 4107-19 (2008) Article DOI: 10.1016/j.bmc.2008.01.017 BindingDB Entry DOI: 10.7270/Q23T9J4N
University of Vienna Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50012957 (1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of human ERG potassium channel				Bioorg Med Chem 16: 4107-19 (2008) Article DOI: 10.1016/j.bmc.2008.01.017 BindingDB Entry DOI: 10.7270/Q23T9J4N
University of Vienna Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%