Affinity Data by PubMed id=18280153

PubMed code 18280153

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50373018 (CHEMBL404507) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by fluorescence anisotropy binding assay				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50373013 (CHEMBL258081) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by fluorescence anisotropy binding assay				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50373014 (CHEMBL404488) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	475	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by fluorescence anisotropy binding assay				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50373013 (CHEMBL258081) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50373015 (CHEMBL258259) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by fluorescence anisotropy binding assay				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50373017 (CHEMBL403238) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by fluorescence anisotropy binding assay				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50373016 (CHEMBL257090) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by fluorescence anisotropy binding assay				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM5802 (5,6-bis(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-ami...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by fluorescence anisotropy binding assay				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM50373013 (CHEMBL258081) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of rat GSK3-beta in L6 cells assessed as accumulation of glycogen				Bioorg Med Chem Lett 18: 1967-71 (2008) Article DOI: 10.1016/j.bmcl.2008.01.113 BindingDB Entry DOI: 10.7270/Q2PR7WV1
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%