Affinity Data by PubMed id=18294852

PubMed code 18294852

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Translocator protein (Rattus norvegicus (rat))	BDBM50054126 ((E)-N-(4-chlorophenyl)-2-(2-(4-chlorophenyl)-1-oxo...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50054125 ((E)-2-(2-(4-chlorophenyl)-1,2-dihydro-1-oxo-3H-pyr...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM22032 (1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Translocator protein (Rattus norvegicus (rat))	BDBM50373041 (CHEMBL260827) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50373042 (CHEMBL260294) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50054140 ((E)-N-benzyl-2-(2-(4-chlorophenyl)-1-oxo-1,2-dihyd...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50054130 ((E)-2-(2-(4-chlorophenyl)-1-oxo-1,2-dihydropyrrolo...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50054138 ((E)-N-benzyl-2-(2-(4-chlorophenyl)-1-oxo-1,2-dihyd...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50373046 (CHEMBL263650) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50373044 (CHEMBL261443) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50373045 (CHEMBL258841) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50373043 (CHEMBL261139) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50373040 (CHEMBL258945) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane				Bioorg Med Chem 16: 3428-37 (2008) Article DOI: 10.1016/j.bmc.2007.06.044 BindingDB Entry DOI: 10.7270/Q21Z458R
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%