Found 15 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50031853
(((3E,7E)-4,8,12-Trimethyl-1-phosphono-trideca-3,7,...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]\[#6]=[#6](/P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C16H30O6P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16(23(17,18)19)24(20,21)22/h7,9,12,15H,5-6,8,10-11H2,1-4H3,(H2,17,18,19)(H2,20,21,22)/b14-9+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM25270
([(6E,11E)-2,6,12,16-tetramethyl-9-phosphonoheptade...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]C([#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C21H38O6P2/c1-17(2)9-7-11-19(5)13-15-21(28(22,23)24,29(25,26)27)16-14-20(6)12-8-10-18(3)4/h9-10,13-14H,7-8,11-12,15-16H2,1-6H3,(H2,22,23,24)(H2,25,26,27)/b19-13+,20-14+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373186
(CHEMBL429860)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]\[#6]=[#6](\P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C16H30O6P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16(23(17,18)19)24(20,21)22/h7,9,12,15H,5-6,8,10-11H2,1-4H3,(H2,17,18,19)(H2,20,21,22)/b14-9- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373191
(CHEMBL260714)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]C([#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C16H30O6P2/c1-13(2)7-6-8-15(5)10-12-16(23(17,18)19,24(20,21)22)11-9-14(3)4/h7,9-10H,6,8,11-12H2,1-5H3,(H2,17,18,19)(H2,20,21,22)/b15-10+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373187
(CHEMBL260713)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]/[#6]C([#6]\[#6]=[#6](\[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C21H38O6P2/c1-17(2)9-7-11-19(5)13-15-21(28(22,23)24,29(25,26)27)16-14-20(6)12-8-10-18(3)4/h9-10,13-14H,7-8,11-12,15-16H2,1-6H3,(H2,22,23,24)(H2,25,26,27)/b19-13-,20-14- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373188
(CHEMBL260712)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]/[#6]C([#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C21H38O6P2/c1-17(2)9-7-11-19(5)13-15-21(28(22,23)24,29(25,26)27)16-14-20(6)12-8-10-18(3)4/h9-10,13-14H,7-8,11-12,15-16H2,1-6H3,(H2,22,23,24)(H2,25,26,27)/b19-13-,20-14+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50031846
(((E)-4,8-Dimethyl-1-phosphono-nona-3,7-dienyl)-pho...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]\[#6]=[#6](\P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C11H22O6P2/c1-9(2)5-4-6-10(3)7-8-11(18(12,13)14)19(15,16)17/h5,8,10H,4,6-7H2,1-3H3,(H2,12,13,14)(H2,15,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50031846
(((E)-4,8-Dimethyl-1-phosphono-nona-3,7-dienyl)-pho...)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]\[#6]=[#6](\P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C11H22O6P2/c1-9(2)5-4-6-10(3)7-8-11(18(12,13)14)19(15,16)17/h5,8,10H,4,6-7H2,1-3H3,(H2,12,13,14)(H2,15,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373190
(CHEMBL259208)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]\[#6]=[#6](\P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C16H30O6P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16(23(17,18)19)24(20,21)22/h7,9,12,15H,5-6,8,10-11H2,1-4H3,(H2,17,18,19)(H2,20,21,22)/b14-9+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373184
(CHEMBL260715)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]/[#6]C([#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C16H30O6P2/c1-13(2)7-6-8-15(5)10-12-16(23(17,18)19,24(20,21)22)11-9-14(3)4/h7,9-10H,6,8,11-12H2,1-5H3,(H2,17,18,19)(H2,20,21,22)/b15-10- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Farnesyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373183
(CHEMBL261582)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]C([#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C11H22O6P2/c1-9(2)5-7-11(18(12,13)14,19(15,16)17)8-6-10(3)4/h5-6H,7-8H2,1-4H3,(H2,12,13,14)(H2,15,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373184
(CHEMBL260715)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]/[#6]C([#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C16H30O6P2/c1-13(2)7-6-8-15(5)10-12-16(23(17,18)19,24(20,21)22)11-9-14(3)4/h7,9-10H,6,8,11-12H2,1-5H3,(H2,17,18,19)(H2,20,21,22)/b15-10- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373185
(CHEMBL261336)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]\[#6]=[#6](\P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C16H30O6P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16(23(17,18)19)24(20,21)22/h7,9,12,15H,5-6,8,10-11H2,1-4H3,(H2,17,18,19)(H2,20,21,22)/b14-9- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373189
(CHEMBL261097)Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]\[#6]=[#6](\P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C11H22O6P2/c1-9(2)5-4-6-10(3)7-8-11(18(12,13)14)19(15,16)17/h5,8,10H,4,6-7H2,1-3H3,(H2,12,13,14)(H2,15,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
Geranylgeranyl pyrophosphate synthase
(Homo sapiens (Human)) | BDBM50373183
(CHEMBL261582)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]C([#6]\[#6]=[#6](\[#6])-[#6])(P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C11H22O6P2/c1-9(2)5-7-11(18(12,13)14,19(15,16)17)8-6-10(3)4/h5-6H,7-8H2,1-4H3,(H2,12,13,14)(H2,15,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GGDPS expressed in BL21 gold bacteria |
Bioorg Med Chem 16: 3652-60 (2008)
Article DOI: 10.1016/j.bmc.2008.02.016
BindingDB Entry DOI: 10.7270/Q2TB17RN |
More data for this
Ligand-Target Pair | |
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