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PubMed code 18321611

Compile data set for download or QSAR
Found 64 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103956
PNG
(2-Isopropoxy-3-[4-(5-m-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cccc(C)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-7-9-18(10-8-16)27-13-20-23-21(29-24-20)17-6-4-5-15(3)11-17/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 79n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103945
PNG
(2-Isopropoxy-3-(4-{2-[5-(2-trifluoromethyl-phenyl)...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccccc2C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H23F3N2O5/c1-14(2)32-19(22(29)30)13-15-7-9-16(10-8-15)31-12-11-20-27-21(33-28-20)17-5-3-4-6-18(17)23(24,25)26/h3-10,14,19H,11-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 2.50E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103955
PNG
(3-(4-((5-(4-tert-butylphenyl)-1,2,4-oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(C)(C)C)cc1)C(O)=O
Show InChI InChI=1S/C25H30N2O5/c1-16(2)31-21(24(28)29)14-17-6-12-20(13-7-17)30-15-22-26-23(32-27-22)18-8-10-19(11-9-18)25(3,4)5/h6-13,16,21H,14-15H2,1-5H3,(H,28,29)
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n/an/an/an/a 3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103946
PNG
(3-(4-((5-(3,5-difluorophenyl)-1,2,4-oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cc(F)cc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C21H20F2N2O5/c1-12(2)29-18(21(26)27)7-13-3-5-17(6-4-13)28-11-19-24-20(30-25-19)14-8-15(22)10-16(23)9-14/h3-6,8-10,12,18H,7,11H2,1-2H3,(H,26,27)
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n/an/an/an/a 100n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103942
PNG
(3-(4-((5-cyclohexyl-1,2,4-oxadiazol-3-yl)methoxy)p...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)C2CCCCC2)cc1)C(O)=O
Show InChI InChI=1S/C21H28N2O5/c1-14(2)27-18(21(24)25)12-15-8-10-17(11-9-15)26-13-19-22-20(28-23-19)16-6-4-3-5-7-16/h8-11,14,16,18H,3-7,12-13H2,1-2H3,(H,24,25)
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n/an/an/an/a 230n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103960
PNG
(3-(4-(2-(5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H23FN2O5/c1-14(2)29-19(22(26)27)12-15-6-8-18(9-7-15)28-11-10-20-24-21(30-25-20)16-4-3-5-17(23)13-16/h3-9,13-14,19H,10-12H2,1-2H3,(H,26,27)
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n/an/an/an/a 2n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103957
PNG
(3-(4-(2-(5-(3,5-bis(trifluoromethyl)phenyl)-1,2,4-...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C24H22F6N2O5/c1-13(2)36-19(22(33)34)9-14-3-5-18(6-4-14)35-8-7-20-31-21(37-32-20)15-10-16(23(25,26)27)12-17(11-15)24(28,29)30/h3-6,10-13,19H,7-9H2,1-2H3,(H,33,34)
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n/an/an/an/a 4n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103943
PNG
(3-(4-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21ClN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 13n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103953
PNG
(3-(4-(2-(5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H23ClN2O5/c1-14(2)29-19(22(26)27)12-15-6-8-18(9-7-15)28-11-10-20-24-21(30-25-20)16-4-3-5-17(23)13-16/h3-9,13-14,19H,10-12H2,1-2H3,(H,26,27)
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n/an/an/an/a 320n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103957
PNG
(3-(4-(2-(5-(3,5-bis(trifluoromethyl)phenyl)-1,2,4-...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C24H22F6N2O5/c1-13(2)36-19(22(33)34)9-14-3-5-18(6-4-14)35-8-7-20-31-21(37-32-20)15-10-16(23(25,26)27)12-17(11-15)24(28,29)30/h3-6,10-13,19H,7-9H2,1-2H3,(H,33,34)
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n/an/an/an/a 50n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103943
PNG
(3-(4-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21ClN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 500n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103959
PNG
(2-Isopropoxy-3-{4-[5-(4-trifluoromethoxy-phenyl)-[...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(OC(F)(F)F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H21F3N2O6/c1-13(2)31-18(21(28)29)11-14-3-7-16(8-4-14)30-12-19-26-20(33-27-19)15-5-9-17(10-6-15)32-22(23,24)25/h3-10,13,18H,11-12H2,1-2H3,(H,28,29)
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n/an/an/an/a 7.90E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103950
PNG
(2-Isopropoxy-3-{4-[5-(4-isopropyl-phenyl)-[1,2,4]o...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(C)C)cc1)C(O)=O
Show InChI InChI=1S/C24H28N2O5/c1-15(2)18-7-9-19(10-8-18)23-25-22(26-31-23)14-29-20-11-5-17(6-12-20)13-21(24(27)28)30-16(3)4/h5-12,15-16,21H,13-14H2,1-4H3,(H,27,28)
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n/an/an/an/a 7.90E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103960
PNG
(3-(4-(2-(5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H23FN2O5/c1-14(2)29-19(22(26)27)12-15-6-8-18(9-7-15)28-11-10-20-24-21(30-25-20)16-4-3-5-17(23)13-16/h3-9,13-14,19H,10-12H2,1-2H3,(H,26,27)
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n/an/an/an/a 4.00E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103955
PNG
(3-(4-((5-(4-tert-butylphenyl)-1,2,4-oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(C)(C)C)cc1)C(O)=O
Show InChI InChI=1S/C25H30N2O5/c1-16(2)31-21(24(28)29)14-17-6-12-20(13-7-17)30-15-22-26-23(32-27-22)18-8-10-19(11-9-18)25(3,4)5/h6-13,16,21H,14-15H2,1-5H3,(H,28,29)
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n/an/an/an/a 40n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103960
PNG
(3-(4-(2-(5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H23FN2O5/c1-14(2)29-19(22(26)27)12-15-6-8-18(9-7-15)28-11-10-20-24-21(30-25-20)16-4-3-5-17(23)13-16/h3-9,13-14,19H,10-12H2,1-2H3,(H,26,27)
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n/an/an/an/a 500n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103949
PNG
(2-Isopropoxy-3-{4-[5-(4-trifluoromethyl-phenyl)-[1...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C22H21F3N2O5/c1-13(2)31-18(21(28)29)11-14-3-9-17(10-4-14)30-12-19-26-20(32-27-19)15-5-7-16(8-6-15)22(23,24)25/h3-10,13,18H,11-12H2,1-2H3,(H,28,29)
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n/an/an/an/a 25n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103944
PNG
(3-(4-(2-(5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H23ClN2O5/c1-14(2)29-19(22(26)27)13-15-3-9-18(10-4-15)28-12-11-20-24-21(30-25-20)16-5-7-17(23)8-6-16/h3-10,14,19H,11-13H2,1-2H3,(H,26,27)
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n/an/an/an/a 25n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103945
PNG
(2-Isopropoxy-3-(4-{2-[5-(2-trifluoromethyl-phenyl)...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccccc2C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H23F3N2O5/c1-14(2)32-19(22(29)30)13-15-7-9-16(10-8-15)31-12-11-20-27-21(33-28-20)17-5-3-4-6-18(17)23(24,25)26/h3-10,14,19H,11-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 160n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103938
PNG
(2-Isopropoxy-3-[4-(5-phenyl-[1,2,4]oxadiazol-3-ylm...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C21H22N2O5/c1-14(2)27-18(21(24)25)12-15-8-10-17(11-9-15)26-13-19-22-20(28-23-19)16-6-4-3-5-7-16/h3-11,14,18H,12-13H2,1-2H3,(H,24,25)
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n/an/an/an/a 1.00E+4n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103940
PNG
(3-(4-((5-(3,5-bis(trifluoromethyl)phenyl)-1,2,4-ox...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H20F6N2O5/c1-12(2)35-18(21(32)33)7-13-3-5-17(6-4-13)34-11-19-30-20(36-31-19)14-8-15(22(24,25)26)10-16(9-14)23(27,28)29/h3-6,8-10,12,18H,7,11H2,1-2H3,(H,32,33)
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n/an/an/an/a 6n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103944
PNG
(3-(4-(2-(5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H23ClN2O5/c1-14(2)29-19(22(26)27)13-15-3-9-18(10-4-15)28-12-11-20-24-21(30-25-20)16-5-7-17(23)8-6-16/h3-10,14,19H,11-13H2,1-2H3,(H,26,27)
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n/an/an/an/a 400n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103941
PNG
(2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(c2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H23F3N2O5/c1-14(2)32-19(22(29)30)12-15-6-8-18(9-7-15)31-11-10-20-27-21(33-28-20)16-4-3-5-17(13-16)23(24,25)26/h3-9,13-14,19H,10-12H2,1-2H3,(H,29,30)
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n/an/an/an/a 200n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103958
PNG
(3-(4-((5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cccc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C21H21FN2O5/c1-13(2)28-18(21(25)26)10-14-6-8-17(9-7-14)27-12-19-23-20(29-24-19)15-4-3-5-16(22)11-15/h3-9,11,13,18H,10,12H2,1-2H3,(H,25,26)
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n/an/an/an/a 100n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103939
PNG
(2-Isopropoxy-3-[4-(5-o-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccccc2C)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-8-10-17(11-9-16)27-13-20-23-21(29-24-20)18-7-5-4-6-15(18)3/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 100n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103956
PNG
(2-Isopropoxy-3-[4-(5-m-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cccc(C)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-7-9-18(10-8-16)27-13-20-23-21(29-24-20)17-6-4-5-15(3)11-17/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 50n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103959
PNG
(2-Isopropoxy-3-{4-[5-(4-trifluoromethoxy-phenyl)-[...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(OC(F)(F)F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H21F3N2O6/c1-13(2)31-18(21(28)29)11-14-3-7-16(8-4-14)30-12-19-26-20(33-27-19)15-5-9-17(10-6-15)32-22(23,24)25/h3-10,13,18H,11-12H2,1-2H3,(H,28,29)
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n/an/an/an/a 63n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103954
PNG
(2-Isopropoxy-3-{4-[2-(5-phenyl-[1,2,4]oxadiazol-3-...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-15(2)28-19(22(25)26)14-16-8-10-18(11-9-16)27-13-12-20-23-21(29-24-20)17-6-4-3-5-7-17/h3-11,15,19H,12-14H2,1-2H3,(H,25,26)
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n/an/an/an/a 13n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103952
PNG
(3-(4-((5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21FN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 7.90E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103956
PNG
(2-Isopropoxy-3-[4-(5-m-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cccc(C)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-7-9-18(10-8-16)27-13-20-23-21(29-24-20)17-6-4-5-15(3)11-17/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 1.60E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103953
PNG
(3-(4-(2-(5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H23ClN2O5/c1-14(2)29-19(22(26)27)12-15-6-8-18(9-7-15)28-11-10-20-24-21(30-25-20)16-4-3-5-17(23)13-16/h3-9,13-14,19H,10-12H2,1-2H3,(H,26,27)
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n/an/an/an/a 100n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103941
PNG
(2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(c2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H23F3N2O5/c1-14(2)32-19(22(29)30)12-15-6-8-18(9-7-15)31-11-10-20-27-21(33-28-20)16-4-3-5-17(13-16)23(24,25)26/h3-9,13-14,19H,10-12H2,1-2H3,(H,29,30)
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n/an/an/an/a 500n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103952
PNG
(3-(4-((5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21FN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 160n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103948
PNG
(2-Isopropoxy-3-[4-(5-p-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(C)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-6-10-18(11-7-16)27-13-20-23-21(29-24-20)17-8-4-15(3)5-9-17/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 25n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103947
PNG
(3-(4-((5-(4-bromophenyl)-1,2,4-oxadiazol-3-yl)meth...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(Br)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21BrN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 40n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103949
PNG
(2-Isopropoxy-3-{4-[5-(4-trifluoromethyl-phenyl)-[1...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C22H21F3N2O5/c1-13(2)31-18(21(28)29)11-14-3-9-17(10-4-14)30-12-19-26-20(32-27-19)15-5-7-16(8-6-15)22(23,24)25/h3-10,13,18H,11-12H2,1-2H3,(H,28,29)
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n/an/an/an/a 32n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103950
PNG
(2-Isopropoxy-3-{4-[5-(4-isopropyl-phenyl)-[1,2,4]o...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(C)C)cc1)C(O)=O
Show InChI InChI=1S/C24H28N2O5/c1-15(2)18-7-9-19(10-8-18)23-25-22(26-31-23)14-29-20-11-5-17(6-12-20)13-21(24(27)28)30-16(3)4/h5-12,15-16,21H,13-14H2,1-4H3,(H,27,28)
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n/an/an/an/a 13n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103943
PNG
(3-(4-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21ClN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 20n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103950
PNG
(2-Isopropoxy-3-{4-[5-(4-isopropyl-phenyl)-[1,2,4]o...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(C)C)cc1)C(O)=O
Show InChI InChI=1S/C24H28N2O5/c1-15(2)18-7-9-19(10-8-18)23-25-22(26-31-23)14-29-20-11-5-17(6-12-20)13-21(24(27)28)30-16(3)4/h5-12,15-16,21H,13-14H2,1-4H3,(H,27,28)
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n/an/an/an/a 4n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103958
PNG
(3-(4-((5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cccc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C21H21FN2O5/c1-13(2)28-18(21(25)26)10-14-6-8-17(9-7-14)27-12-19-23-20(29-24-19)15-4-3-5-16(22)11-15/h3-9,11,13,18H,10,12H2,1-2H3,(H,25,26)
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n/an/an/an/a 7.90E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103939
PNG
(2-Isopropoxy-3-[4-(5-o-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccccc2C)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-8-10-17(11-9-16)27-13-20-23-21(29-24-20)18-7-5-4-6-15(18)3/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 1.60E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103940
PNG
(3-(4-((5-(3,5-bis(trifluoromethyl)phenyl)-1,2,4-ox...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H20F6N2O5/c1-12(2)35-18(21(32)33)7-13-3-5-17(6-4-13)34-11-19-30-20(36-31-19)14-8-15(22(24,25)26)10-16(9-14)23(27,28)29/h3-6,8-10,12,18H,7,11H2,1-2H3,(H,32,33)
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n/an/an/an/a 320n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103945
PNG
(2-Isopropoxy-3-(4-{2-[5-(2-trifluoromethyl-phenyl)...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccccc2C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H23F3N2O5/c1-14(2)32-19(22(29)30)13-15-7-9-16(10-8-15)31-12-11-20-27-21(33-28-20)17-5-3-4-6-18(17)23(24,25)26/h3-10,14,19H,11-13H2,1-2H3,(H,29,30)
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n/an/an/an/a 400n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103938
PNG
(2-Isopropoxy-3-[4-(5-phenyl-[1,2,4]oxadiazol-3-ylm...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C21H22N2O5/c1-14(2)27-18(21(24)25)12-15-8-10-17(11-9-15)26-13-19-22-20(28-23-19)16-6-4-3-5-7-16/h3-11,14,18H,12-13H2,1-2H3,(H,24,25)
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n/an/an/an/a 79n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103952
PNG
(3-(4-((5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21FN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 200n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103941
PNG
(2-Isopropoxy-3-(4-{2-[5-(3-trifluoromethyl-phenyl)...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(c2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H23F3N2O5/c1-14(2)32-19(22(29)30)12-15-6-8-18(9-7-15)31-11-10-20-27-21(33-28-20)16-4-3-5-17(13-16)23(24,25)26/h3-9,13-14,19H,10-12H2,1-2H3,(H,29,30)
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n/an/an/an/a 6n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103947
PNG
(3-(4-((5-(4-bromophenyl)-1,2,4-oxadiazol-3-yl)meth...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(Br)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21BrN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 790n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103955
PNG
(3-(4-((5-(4-tert-butylphenyl)-1,2,4-oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(C)(C)C)cc1)C(O)=O
Show InChI InChI=1S/C25H30N2O5/c1-16(2)31-21(24(28)29)14-17-6-12-20(13-7-17)30-15-22-26-23(32-27-22)18-8-10-19(11-9-18)25(3,4)5/h6-13,16,21H,14-15H2,1-5H3,(H,28,29)
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n/an/an/an/a 5.00E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103946
PNG
(3-(4-((5-(3,5-difluorophenyl)-1,2,4-oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cc(F)cc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C21H20F2N2O5/c1-12(2)29-18(21(26)27)7-13-3-5-17(6-4-13)28-11-19-24-20(30-25-19)14-8-15(22)10-16(23)9-14/h3-6,8-10,12,18H,7,11H2,1-2H3,(H,26,27)
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n/an/an/an/a 160n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103938
PNG
(2-Isopropoxy-3-[4-(5-phenyl-[1,2,4]oxadiazol-3-ylm...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C21H22N2O5/c1-14(2)27-18(21(24)25)12-15-8-10-17(11-9-15)26-13-19-22-20(28-23-19)16-6-4-3-5-7-16/h3-11,14,18H,12-13H2,1-2H3,(H,24,25)
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n/an/an/an/a 160n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103958
PNG
(3-(4-((5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cccc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C21H21FN2O5/c1-13(2)28-18(21(25)26)10-14-6-8-17(9-7-14)27-12-19-23-20(29-24-19)15-4-3-5-16(22)11-15/h3-9,11,13,18H,10,12H2,1-2H3,(H,25,26)
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n/an/an/an/a 79n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103946
PNG
(3-(4-((5-(3,5-difluorophenyl)-1,2,4-oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cc(F)cc(F)c2)cc1)C(O)=O
Show InChI InChI=1S/C21H20F2N2O5/c1-12(2)29-18(21(26)27)7-13-3-5-17(6-4-13)28-11-19-24-20(30-25-19)14-8-15(22)10-16(23)9-14/h3-6,8-10,12,18H,7,11H2,1-2H3,(H,26,27)
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n/an/an/an/a 40n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103942
PNG
(3-(4-((5-cyclohexyl-1,2,4-oxadiazol-3-yl)methoxy)p...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)C2CCCCC2)cc1)C(O)=O
Show InChI InChI=1S/C21H28N2O5/c1-14(2)27-18(21(24)25)12-15-8-10-17(11-9-15)26-13-19-22-20(28-23-19)16-6-4-3-5-7-16/h8-11,14,16,18H,3-7,12-13H2,1-2H3,(H,24,25)
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n/an/an/an/a 240n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103954
PNG
(2-Isopropoxy-3-{4-[2-(5-phenyl-[1,2,4]oxadiazol-3-...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-15(2)28-19(22(25)26)14-16-8-10-18(11-9-16)27-13-12-20-23-21(29-24-20)17-6-4-3-5-7-17/h3-11,15,19H,12-14H2,1-2H3,(H,25,26)
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n/an/an/an/a 2.00E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103948
PNG
(2-Isopropoxy-3-[4-(5-p-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(C)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-6-10-18(11-7-16)27-13-20-23-21(29-24-20)17-8-4-15(3)5-9-17/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 2.50E+3n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))		BDBM50103949
PNG
(2-Isopropoxy-3-{4-[5-(4-trifluoromethyl-phenyl)-[1...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(cc2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C22H21F3N2O5/c1-13(2)31-18(21(28)29)11-14-3-9-17(10-4-14)30-12-19-26-20(32-27-19)15-5-7-16(8-6-15)22(23,24)25/h3-10,13,18H,11-12H2,1-2H3,(H,28,29)
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n/an/an/an/a 500n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARdelta expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103939
PNG
(2-Isopropoxy-3-[4-(5-o-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccccc2C)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-8-10-17(11-9-16)27-13-20-23-21(29-24-20)18-7-5-4-6-15(18)3/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 40n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103951
PNG
(3-(4-(2-(5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccc(F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H23FN2O5/c1-14(2)29-19(22(26)27)13-15-3-9-18(10-4-15)28-12-11-20-24-21(30-25-20)16-5-7-17(23)8-6-16/h3-10,14,19H,11-13H2,1-2H3,(H,26,27)
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n/an/an/an/a 790n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103948
PNG
(2-Isopropoxy-3-[4-(5-p-tolyl-[1,2,4]oxadiazol-3-yl...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(C)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H24N2O5/c1-14(2)28-19(22(25)26)12-16-6-10-18(11-7-16)27-13-20-23-21(29-24-20)17-8-4-15(3)5-9-17/h4-11,14,19H,12-13H2,1-3H3,(H,25,26)
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n/an/an/an/a 16n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103947
PNG
(3-(4-((5-(4-bromophenyl)-1,2,4-oxadiazol-3-yl)meth...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(Br)cc2)cc1)C(O)=O
Show InChI InChI=1S/C21H21BrN2O5/c1-13(2)28-18(21(25)26)11-14-3-9-17(10-4-14)27-12-19-23-20(29-24-19)15-5-7-16(22)8-6-15/h3-10,13,18H,11-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 32n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103940
PNG
(3-(4-((5-(3,5-bis(trifluoromethyl)phenyl)-1,2,4-ox...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C23H20F6N2O5/c1-12(2)35-18(21(32)33)7-13-3-5-17(6-4-13)34-11-19-30-20(36-31-19)14-8-15(22(24,25)26)10-16(9-14)23(27,28)29/h3-6,8-10,12,18H,7,11H2,1-2H3,(H,32,33)
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n/an/an/an/a 32n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103951
PNG
(3-(4-(2-(5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2ccc(F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H23FN2O5/c1-14(2)29-19(22(26)27)13-15-3-9-18(10-4-15)28-12-11-20-24-21(30-25-20)16-5-7-17(23)8-6-16/h3-10,14,19H,11-13H2,1-2H3,(H,26,27)
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n/an/an/an/a 40n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50103953
PNG
(3-(4-(2-(5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl)e...)
Show SMILES CC(C)OC(Cc1ccc(OCCc2noc(n2)-c2cccc(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C22H23ClN2O5/c1-14(2)29-19(22(26)27)12-15-6-8-18(9-7-15)28-11-10-20-24-21(30-25-20)16-4-3-5-17(23)13-16/h3-9,13-14,19H,10-12H2,1-2H3,(H,26,27)
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n/an/an/an/a 4n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Homo sapiens (Human))		BDBM50103959
PNG
(2-Isopropoxy-3-{4-[5-(4-trifluoromethoxy-phenyl)-[...)
Show SMILES CC(C)OC(Cc1ccc(OCc2noc(n2)-c2ccc(OC(F)(F)F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C22H21F3N2O6/c1-13(2)31-18(21(28)29)11-14-3-7-16(8-4-14)30-12-19-26-20(33-27-19)15-5-9-17(10-6-15)32-22(23,24)25/h3-10,13,18H,11-12H2,1-2H3,(H,28,29)
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n/an/an/an/a 20n/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV1 cells cotransfected with Gal4 assessed as reporter activty by transient tra...

Eur J Med Chem 43: 2784-91 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.017
BindingDB Entry DOI: 10.7270/Q2W095QK
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%