Affinity Data by PubMed id=18329886

PubMed code 18329886

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50095155 ((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50080456 ((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261483 (CHEMBL504973 \| YGGWL-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261526 (Ac-YGGFL-NH2 \| CHEMBL500212) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261480 (CHEMBL512955 \| YPWA-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261527 (CHEMBL455502 \| YGWFL-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50209313 ((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	226	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261482 (CHEMBL466147 \| YPAA-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	705	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261481 (CHEMBL445690 \| YAWF-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cells				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50080456 ((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26.1	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261483 (CHEMBL504973 \| YGGWL-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261483 (CHEMBL504973 \| YGGWL-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49.2	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50080456 ((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57.8	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261527 (CHEMBL455502 \| YGWFL-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50261527 (CHEMBL455502 \| YGWFL-NH2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...				Bioorg Med Chem 16: 4341-6 (2008) Article DOI: 10.1016/j.bmc.2008.02.074 BindingDB Entry DOI: 10.7270/Q2MG7P8J
University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%