Found 57 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376061
(CHEMBL409503)Show SMILES NCC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C18H21ClN6/c19-14-3-1-13(2-4-14)9-18(10-20)5-7-25(8-6-18)17-15-16(22-11-21-15)23-12-24-17/h1-4,11-12H,5-10,20H2,(H,21,22,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376067
(CHEMBL260000)Show SMILES NCC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2[nH]ccc12 Show InChI InChI=1S/C19H22ClN5/c20-15-3-1-14(2-4-15)11-19(12-21)6-9-25(10-7-19)18-16-5-8-22-17(16)23-13-24-18/h1-5,8,13H,6-7,9-12,21H2,(H,22,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
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| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376059
(CHEMBL259998)Show InChI InChI=1S/C17H18ClN5/c18-13-3-1-12(2-4-13)17(19)6-9-23(10-7-17)16-14-5-8-20-15(14)21-11-22-16/h1-5,8,11H,6-7,9-10,19H2,(H,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
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UniChem
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PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376060
(CHEMBL407504)Show InChI InChI=1S/C16H17ClN6/c17-12-3-1-11(2-4-12)16(18)5-7-23(8-6-16)15-13-14(20-9-19-13)21-10-22-15/h1-4,9-10H,5-8,18H2,(H,19,20,21,22) | PDB
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| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376063
(CHEMBL406863)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)18(11-20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
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| CHEMBL
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PC sid
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| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376064
(CHEMBL260577)Show InChI InChI=1S/C19H21ClN4/c20-15-3-1-13(2-4-15)18(21)14-7-11-24(12-8-14)17-6-10-23-19-16(17)5-9-22-19/h1-6,9-10,14,18H,7-8,11-12,21H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
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| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376068
(CHEMBL260358)Show InChI InChI=1S/C17H19ClN6/c18-13-3-1-12(2-4-13)17(9-19)5-7-24(8-6-17)16-14-15(21-10-20-14)22-11-23-16/h1-4,10-11H,5-9,19H2,(H,20,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM16232
(6-phenylpurine compound 20 | 6-{4-[4-(4-chlorophen...)Show SMILES Clc1ccc(cc1)C1(CCNCC1)c1ccc(cc1)-c1ncnc2nc[nH]c12 Show InChI InChI=1S/C22H20ClN5/c23-18-7-5-17(6-8-18)22(9-11-24-12-10-22)16-3-1-15(2-4-16)19-20-21(27-13-25-19)28-14-26-20/h1-8,13-14,24H,9-12H2,(H,25,26,27,28) | PDB
UniProtKB/SwissProt
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| MMDB
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| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376062
(CHEMBL260463)Show InChI InChI=1S/C19H21ClN4/c20-15-3-1-14(2-4-15)19(13-21)7-11-24(12-8-19)17-6-10-23-18-16(17)5-9-22-18/h1-6,9-10H,7-8,11-13,21H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376069
(CHEMBL405384)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-12(2-4-14)16(20)13-6-9-24(10-7-13)18-15-5-8-21-17(15)22-11-23-18/h1-5,8,11,13,16H,6-7,9-10,20H2,(H,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376058
(CHEMBL259999)Show InChI InChI=1S/C17H19ClN6/c18-13-3-1-12(2-4-13)9-17(19)5-7-24(8-6-17)16-14-15(21-10-20-14)22-11-23-16/h1-4,10-11H,5-9,19H2,(H,20,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376065
(CHEMBL261034)Show InChI InChI=1S/C17H19ClN6/c18-13-3-1-11(2-4-13)14(19)12-5-7-24(8-6-12)17-15-16(21-9-20-15)22-10-23-17/h1-4,9-10,12,14H,5-8,19H2,(H,20,21,22,23) | PDB
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antibodypedia
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| CHEMBL
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PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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CHEMBL
MCE
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| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of p70S6K by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376057
(CHEMBL259141 | US10227357, Compound P-0541)Show InChI InChI=1S/C11H15N5/c12-8-2-5-16(6-3-8)11-9-1-4-13-10(9)14-7-15-11/h1,4,7-8H,2-3,5-6,12H2,(H,13,14,15) | PDB
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| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376066
(CHEMBL261247)Show InChI InChI=1S/C18H21N5/c19-16(13-4-2-1-3-5-13)14-7-10-23(11-8-14)18-15-6-9-20-17(15)21-12-22-18/h1-6,9,12,14,16H,7-8,10-11,19H2,(H,20,21,22) | PDB
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Similars
| Article
PubMed
| n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376077
(CHEMBL261260)Show InChI InChI=1S/C10H14N6/c11-7-1-3-16(4-2-7)10-8-9(13-5-12-8)14-6-15-10/h5-7H,1-4,11H2,(H,12,13,14,15) | PDB
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| Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376074
(CHEMBL259356)Show InChI InChI=1S/C11H16N6/c12-5-8-1-3-17(4-2-8)11-9-10(14-6-13-9)15-7-16-11/h6-8H,1-5,12H2,(H,13,14,15,16) | PDB
UniProtKB/SwissProt
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| CHEMBL
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PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376063
(CHEMBL406863)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)18(11-20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
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| CHEMBL
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Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376063
(CHEMBL406863)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)18(11-20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
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Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
DrugBank
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PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376064
(CHEMBL260577)Show InChI InChI=1S/C19H21ClN4/c20-15-3-1-13(2-4-15)18(21)14-7-11-24(12-8-14)17-6-10-23-19-16(17)5-9-22-19/h1-6,9-10,14,18H,7-8,11-12,21H2,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM15211
(CHEMBL104264 | H-89 | H89 | HT-89 (H-89) | N-(2-{[...)Show SMILES Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 Show InChI InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+ | PDB
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| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376059
(CHEMBL259998)Show InChI InChI=1S/C17H18ClN5/c18-13-3-1-12(2-4-13)17(19)6-9-23(10-7-17)16-14-5-8-20-15(14)21-11-22-16/h1-5,8,11H,6-7,9-10,19H2,(H,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
NCI pathway
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KEGG
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B.MOAD
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| Purchase
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MCE
MMDB
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UniChem
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| Article
PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376071
(CHEMBL261249)Show InChI InChI=1S/C12H17N5/c13-7-9-2-5-17(6-3-9)12-10-1-4-14-11(10)15-8-16-12/h1,4,8-9H,2-3,5-7,13H2,(H,14,15,16) | PDB
UniProtKB/SwissProt
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| Article
PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376072
(CHEMBL265451)Show InChI InChI=1S/C10H14N6/c11-7-1-3-16(4-2-7)10-8-5-14-15-9(8)12-6-13-10/h5-7H,1-4,11H2,(H,12,13,14,15) | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376070
(CHEMBL264965)Show InChI InChI=1S/C12H16N4/c13-9-3-7-16(8-4-9)11-2-6-15-12-10(11)1-5-14-12/h1-2,5-6,9H,3-4,7-8,13H2,(H,14,15) | PDB
UniProtKB/SwissProt
antibodypedia
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CHEMBL
PC cid
PC sid
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| Article
PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376076
(CHEMBL265193)Show InChI InChI=1S/C11H16N6/c12-5-8-1-3-17(4-2-8)11-9-6-15-16-10(9)13-7-14-11/h6-8H,1-5,12H2,(H,13,14,15,16) | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
UniProtKB/SwissProt
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MCE
MMDB
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| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376059
(CHEMBL259998)Show InChI InChI=1S/C17H18ClN5/c18-13-3-1-12(2-4-13)17(19)6-9-23(10-7-17)16-14-5-8-20-15(14)21-11-22-16/h1-5,8,11H,6-7,9-10,19H2,(H,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376068
(CHEMBL260358)Show InChI InChI=1S/C17H19ClN6/c18-13-3-1-12(2-4-13)17(9-19)5-7-24(8-6-17)16-14-15(21-10-20-14)22-11-23-16/h1-4,10-11H,5-9,19H2,(H,20,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376067
(CHEMBL260000)Show SMILES NCC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2[nH]ccc12 Show InChI InChI=1S/C19H22ClN5/c20-15-3-1-14(2-4-15)11-19(12-21)6-9-25(10-7-19)18-16-5-8-22-17(16)23-13-24-18/h1-5,8,13H,6-7,9-12,21H2,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376062
(CHEMBL260463)Show InChI InChI=1S/C19H21ClN4/c20-15-3-1-14(2-4-15)19(13-21)7-11-24(12-8-19)17-6-10-23-18-16(17)5-9-22-18/h1-6,9-10H,7-8,11-13,21H2,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376067
(CHEMBL260000)Show SMILES NCC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2[nH]ccc12 Show InChI InChI=1S/C19H22ClN5/c20-15-3-1-14(2-4-15)11-19(12-21)6-9-25(10-7-19)18-16-5-8-22-17(16)23-13-24-18/h1-5,8,13H,6-7,9-12,21H2,(H,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376061
(CHEMBL409503)Show SMILES NCC1(Cc2ccc(Cl)cc2)CCN(CC1)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C18H21ClN6/c19-14-3-1-13(2-4-14)9-18(10-20)5-7-25(8-6-18)17-15-16(22-11-21-15)23-12-24-17/h1-4,11-12H,5-10,20H2,(H,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376064
(CHEMBL260577)Show InChI InChI=1S/C19H21ClN4/c20-15-3-1-13(2-4-15)18(21)14-7-11-24(12-8-14)17-6-10-23-19-16(17)5-9-22-19/h1-6,9-10,14,18H,7-8,11-12,21H2,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM16224
(6-phenylpurine compound 6 | N-methyl-1-[4-(9H-puri...)Show InChI InChI=1S/C13H13N5/c1-14-6-9-2-4-10(5-3-9)11-12-13(17-7-15-11)18-8-16-12/h2-5,7-8,14H,6H2,1H3,(H,15,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376069
(CHEMBL405384)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-12(2-4-14)16(20)13-6-9-24(10-7-13)18-15-5-8-21-17(15)22-11-23-18/h1-5,8,11,13,16H,6-7,9-10,20H2,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376069
(CHEMBL405384)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-12(2-4-14)16(20)13-6-9-24(10-7-13)18-15-5-8-21-17(15)22-11-23-18/h1-5,8,11,13,16H,6-7,9-10,20H2,(H,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM12915
(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)Show InChI InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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B.MOAD
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CHEMBL
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MCE
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PC cid
PC sid
PDB
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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CHEMBL
MCE
MMDB
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PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376071
(CHEMBL261249)Show InChI InChI=1S/C12H17N5/c13-7-9-2-5-17(6-3-9)12-10-1-4-14-11(10)15-8-16-12/h1,4,8-9H,2-3,5-7,13H2,(H,14,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376057
(CHEMBL259141 | US10227357, Compound P-0541)Show InChI InChI=1S/C11H15N5/c12-8-2-5-16(6-3-8)11-9-1-4-13-10(9)14-7-15-11/h1,4,7-8H,2-3,5-6,12H2,(H,13,14,15) | PDB
MMDB
NCI pathway
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KEGG
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM15211
(CHEMBL104264 | H-89 | H89 | HT-89 (H-89) | N-(2-{[...)Show SMILES Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 Show InChI InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+ | PDB
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PC cid
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UniChem
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| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376072
(CHEMBL265451)Show InChI InChI=1S/C10H14N6/c11-7-1-3-16(4-2-7)10-8-5-14-15-9(8)12-6-13-10/h5-7H,1-4,11H2,(H,12,13,14,15) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376076
(CHEMBL265193)Show InChI InChI=1S/C11H16N6/c12-5-8-1-3-17(4-2-8)11-9-6-15-16-10(9)13-7-14-11/h6-8H,1-5,12H2,(H,13,14,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50376066
(CHEMBL261247)Show InChI InChI=1S/C18H21N5/c19-16(13-4-2-1-3-5-13)14-7-10-23(11-8-14)18-15-6-9-20-17(15)21-12-22-18/h1-6,9,12,14,16H,7-8,10-11,19H2,(H,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of GSK3-beta in human PC3M cells by ELISA |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376075
(CHEMBL264667)Show InChI InChI=1S/C11H14N6O/c12-9(18)7-1-3-17(4-2-7)11-8-10(14-5-13-8)15-6-16-11/h5-7H,1-4H2,(H2,12,18)(H,13,14,15,16) | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
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KEGG
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CHEMBL
MCE
MMDB
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of CYP1A2 |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
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KEGG
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CHEMBL
MCE
MMDB
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C19 |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2E1
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
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CHEMBL
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PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of CYP2E1 |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
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CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2A6
(Homo sapiens (Human)) | BDBM50237622
(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23) | PDB
MMDB
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UniChem
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| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of CYP2A6 |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM37924
(6-(1-piperidinyl)-7H-purine | 6-piperidin-1-yl-7H-...)Show InChI InChI=1S/C10H13N5/c1-2-4-15(5-3-1)10-8-9(12-6-11-8)13-7-14-10/h6-7H,1-5H2,(H,11,12,13,14) | PDB
UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM16223
(1H-pyrrolo[2,3-b]pyridine | 7-azaindole | compound...)Show InChI InChI=1S/C7H6N2/c1-2-6-3-5-9-7(6)8-4-1/h1-5H,(H,8,9) | PDB
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PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376073
(CHEMBL265194)Show InChI InChI=1S/C11H16N6/c1-7-15-9-10(16-7)13-6-14-11(9)17-4-2-8(12)3-5-17/h6,8H,2-5,12H2,1H3,(H,13,14,15,16) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description
Inhibition of PKBbeta recombinant by radiometric filter binding assay |
J Med Chem 51: 2147-57 (2008)
Article DOI: 10.1021/jm701437d
BindingDB Entry DOI: 10.7270/Q2X63NV8 |
More data for this
Ligand-Target Pair | |
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