Found 42 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375237
(CHEMBL272114)Show SMILES Cn1cnc2cc(C#N)c(c(CN)c12)-c1ccccc1Cl |(-4.05,-1.64,;-3.57,-.17,;-4.48,1.07,;-3.57,2.32,;-2.11,1.84,;-.78,2.61,;.56,1.84,;1.89,2.61,;3.22,3.38,;.56,.3,;-.78,-.47,;-.78,-2.01,;-2.11,-2.78,;-2.11,.3,;1.89,-.47,;3.22,.3,;4.56,-.47,;4.56,-2.01,;3.22,-2.78,;1.89,-2.01,;.56,-2.78,)| Show InChI InChI=1S/C16H13ClN4/c1-21-9-20-14-6-10(7-18)15(12(8-19)16(14)21)11-4-2-3-5-13(11)17/h2-6,9H,8,19H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| MMDB
PDB
Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375229
(CHEMBL261246)Show InChI InChI=1S/C20H17ClN4/c1-25-19-16(11-22)14(15-6-2-3-7-17(15)21)8-9-18(19)24-20(25)13-5-4-10-23-12-13/h2-10,12H,11,22H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375228
(CHEMBL273209)Show SMILES Cn1cnc2cc(C(N)=O)c(c(CN)c12)-c1ccccc1Cl |(-.2,-21.79,;-.66,-23.26,;.26,-24.51,;-.64,-25.77,;-2.12,-25.3,;-3.46,-26.07,;-4.79,-25.31,;-6.13,-26.08,;-7.46,-25.31,;-6.13,-27.62,;-4.79,-23.76,;-3.47,-22.99,;-3.47,-21.45,;-2.14,-20.68,;-2.13,-23.75,;-6.12,-23,;-7.46,-23.77,;-8.79,-23,;-8.79,-21.45,;-7.46,-20.68,;-6.13,-21.45,;-4.8,-20.67,)| Show InChI InChI=1S/C16H15ClN4O/c1-21-8-20-13-6-10(16(19)22)14(11(7-18)15(13)21)9-4-2-3-5-12(9)17/h2-6,8H,7,18H2,1H3,(H2,19,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375240
(CHEMBL257653)Show SMILES Cn1cnc2cc(Br)c(-c3ccccc3Cl)c(CN)c12 |(1.6,-10.59,;1.13,-12.06,;2.06,-13.3,;1.16,-14.56,;-.32,-14.1,;-1.66,-14.87,;-3,-14.1,;-4.33,-14.87,;-3,-12.56,;-4.32,-11.79,;-5.66,-12.56,;-6.99,-11.79,;-6.99,-10.25,;-5.66,-9.48,;-4.33,-10.24,;-3,-9.47,;-1.67,-11.79,;-1.68,-10.25,;-.35,-9.47,;-.34,-12.55,)| Show InChI InChI=1S/C15H13BrClN3/c1-20-8-19-13-6-11(16)14(10(7-18)15(13)20)9-4-2-3-5-12(9)17/h2-6,8H,7,18H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375238
(CHEMBL257852)Show InChI InChI=1S/C15H14ClN3O/c1-19-14-11(8-17)9(6-7-13(14)18-15(19)20)10-4-2-3-5-12(10)16/h2-7H,8,17H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375241
(CHEMBL256266)Show InChI InChI=1S/C14H13ClN4/c1-19-14-11(8-16)9(6-7-13(14)17-18-19)10-4-2-3-5-12(10)15/h2-7H,8,16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375245
(CHEMBL255552)Show InChI InChI=1S/C15H13Cl2N3/c1-20-8-19-14-5-4-10(12(7-18)15(14)20)11-3-2-9(16)6-13(11)17/h2-6,8H,7,18H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375236
(CHEMBL270365)Show InChI InChI=1S/C15H14ClN3/c1-19-9-18-14-7-6-10(12(8-17)15(14)19)11-4-2-3-5-13(11)16/h2-7,9H,8,17H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375230
(CHEMBL263137)Show InChI InChI=1S/C17H18ClN3O/c1-21-16(10-22-2)20-15-8-7-11(13(9-19)17(15)21)12-5-3-4-6-14(12)18/h3-8H,9-10,19H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375233
(CHEMBL257308)Show InChI InChI=1S/C16H15Cl2N3/c1-2-21-9-20-15-6-5-11(13(8-19)16(15)21)12-4-3-10(17)7-14(12)18/h3-7,9H,2,8,19H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375232
(CHEMBL401542)Show InChI InChI=1S/C16H16ClN3O/c17-14-4-2-1-3-12(14)11-5-6-15-16(13(11)9-18)20(7-8-21)10-19-15/h1-6,10,21H,7-9,18H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375231
(CHEMBL263139)Show InChI InChI=1S/C17H18ClN3/c1-3-16-20-15-9-8-11(12-6-4-5-7-14(12)18)13(10-19)17(15)21(16)2/h4-9H,3,10,19H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375235
(CHEMBL256625)Show InChI InChI=1S/C16H17N3/c1-11-5-3-4-6-12(11)13-7-8-15-16(14(13)9-17)19(2)10-18-15/h3-8,10H,9,17H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375242
(CHEMBL403156)Show InChI InChI=1S/C21H18ClN3/c22-19-9-5-4-8-17(19)16-10-11-20-21(18(16)12-23)25(14-24-20)13-15-6-2-1-3-7-15/h1-11,14H,12-13,23H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375249
(CHEMBL257636)Show InChI InChI=1S/C16H16ClN3/c1-10-19-15-8-7-11(12-5-3-4-6-14(12)17)13(9-18)16(15)20(10)2/h3-8H,9,18H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375244
(CHEMBL272771)Show InChI InChI=1S/C15H13ClFN3/c1-20-8-19-14-5-3-10(12(7-18)15(14)20)11-6-9(17)2-4-13(11)16/h2-6,8H,7,18H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375225
(CHEMBL256252)Show InChI InChI=1S/C16H17N3O/c1-19-10-18-15-7-6-13(14(8-17)16(15)19)12-5-3-2-4-11(12)9-20/h2-7,10,20H,8-9,17H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375234
(CHEMBL404544)Show InChI InChI=1S/C14H11Cl2N3/c15-8-1-2-10(12(16)5-8)9-3-4-13-14(11(9)6-17)19-7-18-13/h1-5,7H,6,17H2,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375243
(CHEMBL406201)Show InChI InChI=1S/C15H13F2N3/c1-20-8-19-14-5-4-10(12(7-18)15(14)20)11-3-2-9(16)6-13(11)17/h2-6,8H,7,18H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375248
(CHEMBL255769)Show InChI InChI=1S/C15H15N3/c1-18-10-17-14-8-7-12(13(9-16)15(14)18)11-5-3-2-4-6-11/h2-8,10H,9,16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375246
(CHEMBL256624)Show InChI InChI=1S/C15H15N3O/c1-18-9-17-13-7-6-10(12(8-16)15(13)18)11-4-2-3-5-14(11)19/h2-7,9,19H,8,16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375247
(CHEMBL428065)Show InChI InChI=1S/C16H17N3O/c1-19-10-18-14-8-7-11(13(9-17)16(14)19)12-5-3-4-6-15(12)20-2/h3-8,10H,9,17H2,1-2H3 | PDB
MMDB
Reactome pathway
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PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375229
(CHEMBL261246)Show InChI InChI=1S/C20H17ClN4/c1-25-19-16(11-22)14(15-6-2-3-7-17(15)21)8-9-18(19)24-20(25)13-5-4-10-23-12-13/h2-10,12H,11,22H2,1H3 | PDB
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| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375250
(CHEMBL256826)Show InChI InChI=1S/C16H16N4O/c1-20-9-19-14-7-6-11(13(8-17)15(14)20)10-4-2-3-5-12(10)16(18)21/h2-7,9H,8,17H2,1H3,(H2,18,21) | PDB
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| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375227
(CHEMBL255554)Show InChI InChI=1S/C14H13N3/c15-8-12-11(10-4-2-1-3-5-10)6-7-13-14(12)17-9-16-13/h1-7,9H,8,15H2,(H,16,17) | PDB
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| Article
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| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375232
(CHEMBL401542)Show InChI InChI=1S/C16H16ClN3O/c17-14-4-2-1-3-12(14)11-5-6-15-16(13(11)9-18)20(7-8-21)10-19-15/h1-6,10,21H,7-9,18H2 | PDB
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| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375245
(CHEMBL255552)Show InChI InChI=1S/C15H13Cl2N3/c1-20-8-19-14-5-4-10(12(7-18)15(14)20)11-3-2-9(16)6-13(11)17/h2-6,8H,7,18H2,1H3 | PDB
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| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375239
(CHEMBL257036)Show InChI InChI=1S/C13H13N/c14-10-12-8-4-5-9-13(12)11-6-2-1-3-7-11/h1-9H,10,14H2 | PDB
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UniChem
| MMDB
PDB
Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375228
(CHEMBL273209)Show SMILES Cn1cnc2cc(C(N)=O)c(c(CN)c12)-c1ccccc1Cl |(-.2,-21.79,;-.66,-23.26,;.26,-24.51,;-.64,-25.77,;-2.12,-25.3,;-3.46,-26.07,;-4.79,-25.31,;-6.13,-26.08,;-7.46,-25.31,;-6.13,-27.62,;-4.79,-23.76,;-3.47,-22.99,;-3.47,-21.45,;-2.14,-20.68,;-2.13,-23.75,;-6.12,-23,;-7.46,-23.77,;-8.79,-23,;-8.79,-21.45,;-7.46,-20.68,;-6.13,-21.45,;-4.8,-20.67,)| Show InChI InChI=1S/C16H15ClN4O/c1-21-8-20-13-6-10(16(19)22)14(11(7-18)15(13)21)9-4-2-3-5-12(9)17/h2-6,8H,7,18H2,1H3,(H2,19,22) | PDB
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| n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375231
(CHEMBL263139)Show InChI InChI=1S/C17H18ClN3/c1-3-16-20-15-9-8-11(12-6-4-5-7-14(12)18)13(10-19)17(15)21(16)2/h4-9H,3,10,19H2,1-2H3 | PDB
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| n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375234
(CHEMBL404544)Show InChI InChI=1S/C14H11Cl2N3/c15-8-1-2-10(12(16)5-8)9-3-4-13-14(11(9)6-17)19-7-18-13/h1-5,7H,6,17H2,(H,18,19) | PDB
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| n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375230
(CHEMBL263137)Show InChI InChI=1S/C17H18ClN3O/c1-21-16(10-22-2)20-15-8-7-11(13(9-19)17(15)21)12-5-3-4-6-14(12)18/h3-8H,9-10,19H2,1-2H3 | PDB
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| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50375226
(CHEMBL403862)Show InChI InChI=1S/C15H15N3/c1-18-10-17-15-13(9-16)12(7-8-14(15)18)11-5-3-2-4-6-11/h2-8,10H,9,16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
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UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of human DPP4 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375241
(CHEMBL256266)Show InChI InChI=1S/C14H13ClN4/c1-19-14-11(8-16)9(6-7-13(14)17-18-19)10-4-2-3-5-12(10)15/h2-7H,8,16H2,1H3 | PDB
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| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375233
(CHEMBL257308)Show InChI InChI=1S/C16H15Cl2N3/c1-2-21-9-20-15-6-5-11(13(8-19)16(15)21)12-4-3-10(17)7-14(12)18/h3-7,9H,2,8,19H2,1H3 | PDB
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| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375236
(CHEMBL270365)Show InChI InChI=1S/C15H14ClN3/c1-19-9-18-14-7-6-10(12(8-17)15(14)19)11-4-2-3-5-13(11)16/h2-7,9H,8,17H2,1H3 | PDB
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| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375248
(CHEMBL255769)Show InChI InChI=1S/C15H15N3/c1-18-10-17-14-8-7-12(13(9-16)15(14)18)11-5-3-2-4-6-11/h2-8,10H,9,16H2,1H3 | PDB
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| Article
PubMed
| n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375235
(CHEMBL256625)Show InChI InChI=1S/C16H17N3/c1-11-5-3-4-6-12(11)13-7-8-15-16(14(13)9-17)19(2)10-18-15/h3-8,10H,9,17H2,1-2H3 | PDB
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| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375238
(CHEMBL257852)Show InChI InChI=1S/C15H14ClN3O/c1-19-14-11(8-17)9(6-7-13(14)18-15(19)20)10-4-2-3-5-12(10)16/h2-7H,8,17H2,1H3,(H,18,20) | PDB
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| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375240
(CHEMBL257653)Show SMILES Cn1cnc2cc(Br)c(-c3ccccc3Cl)c(CN)c12 |(1.6,-10.59,;1.13,-12.06,;2.06,-13.3,;1.16,-14.56,;-.32,-14.1,;-1.66,-14.87,;-3,-14.1,;-4.33,-14.87,;-3,-12.56,;-4.32,-11.79,;-5.66,-12.56,;-6.99,-11.79,;-6.99,-10.25,;-5.66,-9.48,;-4.33,-10.24,;-3,-9.47,;-1.67,-11.79,;-1.68,-10.25,;-.35,-9.47,;-.34,-12.55,)| Show InChI InChI=1S/C15H13BrClN3/c1-20-8-19-13-6-11(16)14(10(7-18)15(13)20)9-4-2-3-5-12(9)17/h2-6,8H,7,18H2,1H3 | PDB
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| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375242
(CHEMBL403156)Show InChI InChI=1S/C21H18ClN3/c22-19-9-5-4-8-17(19)16-10-11-20-21(18(16)12-23)25(14-24-20)13-15-6-2-1-3-7-15/h1-11,14H,12-13,23H2 | PDB
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| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50375237
(CHEMBL272114)Show SMILES Cn1cnc2cc(C#N)c(c(CN)c12)-c1ccccc1Cl |(-4.05,-1.64,;-3.57,-.17,;-4.48,1.07,;-3.57,2.32,;-2.11,1.84,;-.78,2.61,;.56,1.84,;1.89,2.61,;3.22,3.38,;.56,.3,;-.78,-.47,;-.78,-2.01,;-2.11,-2.78,;-2.11,.3,;1.89,-.47,;3.22,.3,;4.56,-.47,;4.56,-2.01,;3.22,-2.78,;1.89,-2.01,;.56,-2.78,)| Show InChI InChI=1S/C16H13ClN4/c1-21-9-20-14-6-10(7-18)15(12(8-19)16(14)21)11-4-2-3-5-13(11)17/h2-6,9H,8,19H2,1H3 | PDB
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| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda San Diego
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 |
Bioorg Med Chem Lett 18: 2362-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.071
BindingDB Entry DOI: 10.7270/Q29P32GJ |
More data for this
Ligand-Target Pair | |
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