Found 79 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376359
(CHEMBL260092)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-2-1-3-15(10-13)30-20(32)29-14-6-4-12(5-7-14)16-8-9-26-19-17(31-16)18(25)27-11-28-19/h1-7,10-11H,8-9H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376343
(CHEMBL411903)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-14-6-3-12(21(23,24)25)9-16(14)32-20(33)30-13-4-1-11(2-5-13)15-7-8-27-19-17(31-15)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,32,33)(H3,26,27,28,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376357
(CHEMBL410731)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(c2F)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-16-13(21(23,24)25)2-1-3-15(16)32-20(33)30-12-6-4-11(5-7-12)14-8-9-27-19-17(31-14)18(26)28-10-29-19/h1-7,10H,8-9H2,(H2,30,32,33)(H3,26,27,28,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376359
(CHEMBL260092)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-2-1-3-15(10-13)30-20(32)29-14-6-4-12(5-7-14)16-8-9-26-19-17(31-16)18(25)27-11-28-19/h1-7,10-11H,8-9H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376343
(CHEMBL411903)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-14-6-3-12(21(23,24)25)9-16(14)32-20(33)30-13-4-1-11(2-5-13)15-7-8-27-19-17(31-15)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,32,33)(H3,26,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376356
(CHEMBL429516)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(F)c(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-15-6-5-13(9-14(15)21(23,24)25)31-20(33)30-12-3-1-11(2-4-12)16-7-8-27-19-17(32-16)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,31,33)(H3,26,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376363
(CHEMBL409872)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 |c:9| Show InChI InChI=1S/C20H18ClN7O/c21-13-2-1-3-15(10-13)27-20(29)26-14-6-4-12(5-7-14)16-8-9-23-19-17(28-16)18(22)24-11-25-19/h1-7,10-11H,8-9H2,(H2,26,27,29)(H3,22,23,24,25) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376359
(CHEMBL260092)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-2-1-3-15(10-13)30-20(32)29-14-6-4-12(5-7-14)16-8-9-26-19-17(31-16)18(25)27-11-28-19/h1-7,10-11H,8-9H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376355
(CHEMBL412102)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17ClF3N7O/c22-15-6-5-13(9-14(15)21(23,24)25)31-20(33)30-12-3-1-11(2-4-12)16-7-8-27-19-17(32-16)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,31,33)(H3,26,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376353
(CHEMBL403706)Show SMILES Cc1ccc(cc1NC(=O)Nc1cccc(c1)C(F)(F)F)C1=Nc2c(N)ncnc2NCC1 |t:23| Show InChI InChI=1S/C22H20F3N7O/c1-12-5-6-13(16-7-8-27-20-18(31-16)19(26)28-11-29-20)9-17(12)32-21(33)30-15-4-2-3-14(10-15)22(23,24)25/h2-6,9-11H,7-8H2,1H3,(H2,30,32,33)(H3,26,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376356
(CHEMBL429516)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(F)c(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-15-6-5-13(9-14(15)21(23,24)25)31-20(33)30-12-3-1-11(2-4-12)16-7-8-27-19-17(32-16)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,31,33)(H3,26,27,28,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376358
(CHEMBL259013)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-3-7-15(8-4-13)30-20(32)29-14-5-1-12(2-6-14)16-9-10-26-19-17(31-16)18(25)27-11-28-19/h1-8,11H,9-10H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376343
(CHEMBL411903)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-14-6-3-12(21(23,24)25)9-16(14)32-20(33)30-13-4-1-11(2-5-13)15-7-8-27-19-17(31-15)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,32,33)(H3,26,27,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376353
(CHEMBL403706)Show SMILES Cc1ccc(cc1NC(=O)Nc1cccc(c1)C(F)(F)F)C1=Nc2c(N)ncnc2NCC1 |t:23| Show InChI InChI=1S/C22H20F3N7O/c1-12-5-6-13(16-7-8-27-20-18(31-16)19(26)28-11-29-20)9-17(12)32-21(33)30-15-4-2-3-14(10-15)22(23,24)25/h2-6,9-11H,7-8H2,1H3,(H2,30,32,33)(H3,26,27,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376359
(CHEMBL260092)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-2-1-3-15(10-13)30-20(32)29-14-6-4-12(5-7-14)16-8-9-26-19-17(31-16)18(25)27-11-28-19/h1-7,10-11H,8-9H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376362
(CHEMBL262607)Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)C2=Nc3c(N)ncnc3NCC2)c1 |t:18| Show InChI InChI=1S/C21H20FN7O/c1-12-2-7-15(22)17(10-12)29-21(30)27-14-5-3-13(4-6-14)16-8-9-24-20-18(28-16)19(23)25-11-26-20/h2-7,10-11H,8-9H2,1H3,(H2,27,29,30)(H3,23,24,25,26) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376355
(CHEMBL412102)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17ClF3N7O/c22-15-6-5-13(9-14(15)21(23,24)25)31-20(33)30-12-3-1-11(2-4-12)16-7-8-27-19-17(32-16)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,31,33)(H3,26,27,28,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376363
(CHEMBL409872)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 |c:9| Show InChI InChI=1S/C20H18ClN7O/c21-13-2-1-3-15(10-13)27-20(29)26-14-6-4-12(5-7-14)16-8-9-23-19-17(28-16)18(22)24-11-25-19/h1-7,10-11H,8-9H2,(H2,26,27,29)(H3,22,23,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376363
(CHEMBL409872)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 |c:9| Show InChI InChI=1S/C20H18ClN7O/c21-13-2-1-3-15(10-13)27-20(29)26-14-6-4-12(5-7-14)16-8-9-23-19-17(28-16)18(22)24-11-25-19/h1-7,10-11H,8-9H2,(H2,26,27,29)(H3,22,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376356
(CHEMBL429516)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(F)c(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-15-6-5-13(9-14(15)21(23,24)25)31-20(33)30-12-3-1-11(2-4-12)16-7-8-27-19-17(32-16)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,31,33)(H3,26,27,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376357
(CHEMBL410731)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(c2F)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-16-13(21(23,24)25)2-1-3-15(16)32-20(33)30-12-6-4-11(5-7-12)14-8-9-27-19-17(31-14)18(26)28-10-29-19/h1-7,10H,8-9H2,(H2,30,32,33)(H3,26,27,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376358
(CHEMBL259013)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-3-7-15(8-4-13)30-20(32)29-14-5-1-12(2-6-14)16-9-10-26-19-17(31-16)18(25)27-11-28-19/h1-8,11H,9-10H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376362
(CHEMBL262607)Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)C2=Nc3c(N)ncnc3NCC2)c1 |t:18| Show InChI InChI=1S/C21H20FN7O/c1-12-2-7-15(22)17(10-12)29-21(30)27-14-5-3-13(4-6-14)16-8-9-24-20-18(28-16)19(23)25-11-26-20/h2-7,10-11H,8-9H2,1H3,(H2,27,29,30)(H3,23,24,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376357
(CHEMBL410731)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(c2F)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-16-13(21(23,24)25)2-1-3-15(16)32-20(33)30-12-6-4-11(5-7-12)14-8-9-27-19-17(31-14)18(26)28-10-29-19/h1-7,10H,8-9H2,(H2,30,32,33)(H3,26,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376355
(CHEMBL412102)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17ClF3N7O/c22-15-6-5-13(9-14(15)21(23,24)25)31-20(33)30-12-3-1-11(2-4-12)16-7-8-27-19-17(32-16)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,31,33)(H3,26,27,28,29) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376363
(CHEMBL409872)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 |c:9| Show InChI InChI=1S/C20H18ClN7O/c21-13-2-1-3-15(10-13)27-20(29)26-14-6-4-12(5-7-14)16-8-9-23-19-17(28-16)18(22)24-11-25-19/h1-7,10-11H,8-9H2,(H2,26,27,29)(H3,22,23,24,25) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376355
(CHEMBL412102)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17ClF3N7O/c22-15-6-5-13(9-14(15)21(23,24)25)31-20(33)30-12-3-1-11(2-4-12)16-7-8-27-19-17(32-16)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,31,33)(H3,26,27,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376353
(CHEMBL403706)Show SMILES Cc1ccc(cc1NC(=O)Nc1cccc(c1)C(F)(F)F)C1=Nc2c(N)ncnc2NCC1 |t:23| Show InChI InChI=1S/C22H20F3N7O/c1-12-5-6-13(16-7-8-27-20-18(31-16)19(26)28-11-29-20)9-17(12)32-21(33)30-15-4-2-3-14(10-15)22(23,24)25/h2-6,9-11H,7-8H2,1H3,(H2,30,32,33)(H3,26,27,28,29) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376362
(CHEMBL262607)Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)C2=Nc3c(N)ncnc3NCC2)c1 |t:18| Show InChI InChI=1S/C21H20FN7O/c1-12-2-7-15(22)17(10-12)29-21(30)27-14-5-3-13(4-6-14)16-8-9-24-20-18(28-16)19(23)25-11-26-20/h2-7,10-11H,8-9H2,1H3,(H2,27,29,30)(H3,23,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376361
(CHEMBL260848)Show SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2cccc(c2)C(F)(F)F)c1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-4-2-6-15(10-13)30-20(32)29-14-5-1-3-12(9-14)16-7-8-26-19-17(31-16)18(25)27-11-28-19/h1-6,9-11H,7-8H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376358
(CHEMBL259013)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-3-7-15(8-4-13)30-20(32)29-14-5-1-12(2-6-14)16-9-10-26-19-17(31-16)18(25)27-11-28-19/h1-8,11H,9-10H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376343
(CHEMBL411903)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-14-6-3-12(21(23,24)25)9-16(14)32-20(33)30-13-4-1-11(2-5-13)15-7-8-27-19-17(31-15)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,32,33)(H3,26,27,28,29) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376361
(CHEMBL260848)Show SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2cccc(c2)C(F)(F)F)c1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-4-2-6-15(10-13)30-20(32)29-14-5-1-3-12(9-14)16-7-8-26-19-17(31-16)18(25)27-11-28-19/h1-6,9-11H,7-8H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376353
(CHEMBL403706)Show SMILES Cc1ccc(cc1NC(=O)Nc1cccc(c1)C(F)(F)F)C1=Nc2c(N)ncnc2NCC1 |t:23| Show InChI InChI=1S/C22H20F3N7O/c1-12-5-6-13(16-7-8-27-20-18(31-16)19(26)28-11-29-20)9-17(12)32-21(33)30-15-4-2-3-14(10-15)22(23,24)25/h2-6,9-11H,7-8H2,1H3,(H2,30,32,33)(H3,26,27,28,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376361
(CHEMBL260848)Show SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2cccc(c2)C(F)(F)F)c1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-4-2-6-15(10-13)30-20(32)29-14-5-1-3-12(9-14)16-7-8-26-19-17(31-16)18(25)27-11-28-19/h1-6,9-11H,7-8H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376362
(CHEMBL262607)Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)C2=Nc3c(N)ncnc3NCC2)c1 |t:18| Show InChI InChI=1S/C21H20FN7O/c1-12-2-7-15(22)17(10-12)29-21(30)27-14-5-3-13(4-6-14)16-8-9-24-20-18(28-16)19(23)25-11-26-20/h2-7,10-11H,8-9H2,1H3,(H2,27,29,30)(H3,23,24,25,26) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376356
(CHEMBL429516)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(F)c(c2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-15-6-5-13(9-14(15)21(23,24)25)31-20(33)30-12-3-1-11(2-4-12)16-7-8-27-19-17(32-16)18(26)28-10-29-19/h1-6,9-10H,7-8H2,(H2,30,31,33)(H3,26,27,28,29) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 345 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376348
(CHEMBL407532)Show InChI InChI=1S/C13H12ClN5/c14-9-3-1-2-8(6-9)10-4-5-16-13-11(19-10)12(15)17-7-18-13/h1-3,6-7H,4-5H2,(H3,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 10 uM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376361
(CHEMBL260848)Show SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2cccc(c2)C(F)(F)F)c1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-4-2-6-15(10-13)30-20(32)29-14-5-1-3-12(9-14)16-7-8-26-19-17(31-16)18(25)27-11-28-19/h1-6,9-11H,7-8H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376354
(CHEMBL263374)Show SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2ccccc2)c1 |c:9| Show InChI InChI=1S/C20H19N7O/c21-18-17-19(24-12-23-18)22-10-9-16(27-17)13-5-4-8-15(11-13)26-20(28)25-14-6-2-1-3-7-14/h1-8,11-12H,9-10H2,(H2,25,26,28)(H3,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 888 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376352
(CHEMBL260093)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccccc2)cc1 |c:9| Show InChI InChI=1S/C20H19N7O/c21-18-17-19(24-12-23-18)22-11-10-16(27-17)13-6-8-15(9-7-13)26-20(28)25-14-4-2-1-3-5-14/h1-9,12H,10-11H2,(H2,25,26,28)(H3,21,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 951 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376357
(CHEMBL410731)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2cccc(c2F)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H17F4N7O/c22-16-13(21(23,24)25)2-1-3-15(16)32-20(33)30-12-6-4-11(5-7-12)14-8-9-27-19-17(31-14)18(26)28-10-29-19/h1-7,10H,8-9H2,(H2,30,32,33)(H3,26,27,28,29) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50376358
(CHEMBL259013)Show SMILES Nc1ncnc2NCCC(=Nc12)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 |c:9| Show InChI InChI=1S/C21H18F3N7O/c22-21(23,24)13-3-7-15(8-4-13)30-20(32)29-14-5-1-12(2-6-14)16-9-10-26-19-17(31-16)18(25)27-11-28-19/h1-8,11H,9-10H2,(H2,29,30,32)(H3,25,26,27,28) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cells |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376354
(CHEMBL263374)Show SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2ccccc2)c1 |c:9| Show InChI InChI=1S/C20H19N7O/c21-18-17-19(24-12-23-18)22-10-9-16(27-17)13-5-4-8-15(11-13)26-20(28)25-14-6-2-1-3-7-14/h1-8,11-12H,9-10H2,(H2,25,26,28)(H3,21,22,23,24) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50376360
(CHEMBL409839)Show SMILES Nc1nc(N)c2N=C(CCNc2n1)c1ccc(NC(=O)Nc2ccccc2)cc1 |c:6| Show InChI InChI=1S/C20H20N8O/c21-17-16-18(28-19(22)27-17)23-11-10-15(26-16)12-6-8-14(9-7-12)25-20(29)24-13-4-2-1-3-5-13/h1-9H,10-11H2,(H2,24,25,29)(H5,21,22,23,27,28) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376344
(CHEMBL262623)Show InChI InChI=1S/C13H13N5/c14-12-11-13(17-8-16-12)15-7-6-10(18-11)9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H3,14,15,16,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 10 uM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376347
(CHEMBL407265)Show InChI InChI=1S/C13H12ClN5/c14-9-3-1-8(2-4-9)10-5-6-16-13-11(19-10)12(15)17-7-18-13/h1-4,7H,5-6H2,(H3,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 10 uM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376350
(CHEMBL263902)Show InChI InChI=1S/C14H15N5/c1-9-3-2-4-10(7-9)11-5-6-16-14-12(19-11)13(15)17-8-18-14/h2-4,7-8H,5-6H2,1H3,(H3,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 10 uM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376354
(CHEMBL263374)Show SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2ccccc2)c1 |c:9| Show InChI InChI=1S/C20H19N7O/c21-18-17-19(24-12-23-18)22-10-9-16(27-17)13-5-4-8-15(11-13)26-20(28)25-14-6-2-1-3-7-14/h1-8,11-12H,9-10H2,(H2,25,26,28)(H3,21,22,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376349
(CHEMBL405233)Show InChI InChI=1S/C14H15N5/c1-9-2-4-10(5-3-9)11-6-7-16-14-12(19-11)13(15)17-8-18-14/h2-5,8H,6-7H2,1H3,(H3,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 10 uM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376345
(CHEMBL260620)Show InChI InChI=1S/C13H13ClN6/c14-8-3-1-7(2-4-8)9-5-6-17-12-10(18-9)11(15)19-13(16)20-12/h1-4H,5-6H2,(H5,15,16,17,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 10 uM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50376360
(CHEMBL409839)Show SMILES Nc1nc(N)c2N=C(CCNc2n1)c1ccc(NC(=O)Nc2ccccc2)cc1 |c:6| Show InChI InChI=1S/C20H20N8O/c21-17-16-18(28-19(22)27-17)23-11-10-15(26-16)12-6-8-14(9-7-12)25-20(29)24-13-4-2-1-3-5-13/h1-9H,10-11H2,(H2,24,25,29)(H5,21,22,23,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of cKit |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376360
(CHEMBL409839)Show SMILES Nc1nc(N)c2N=C(CCNc2n1)c1ccc(NC(=O)Nc2ccccc2)cc1 |c:6| Show InChI InChI=1S/C20H20N8O/c21-17-16-18(28-19(22)27-17)23-11-10-15(26-16)12-6-8-14(9-7-12)25-20(29)24-13-4-2-1-3-5-13/h1-9H,10-11H2,(H2,24,25,29)(H5,21,22,23,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 1 mM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376346
(CHEMBL259381)Show InChI InChI=1S/C13H13ClN6/c14-8-3-1-2-7(6-8)9-4-5-17-12-10(18-9)11(15)19-13(16)20-12/h1-3,6H,4-5H2,(H5,15,16,17,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 10 uM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376351
(CHEMBL259380)Show InChI InChI=1S/C13H14N6/c14-11-10-12(19-13(15)18-11)16-7-6-9(17-10)8-4-2-1-3-5-8/h1-5H,6-7H2,(H5,14,15,16,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR in presence of 10 uM ATP |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50376350
(CHEMBL263902)Show InChI InChI=1S/C14H15N5/c1-9-3-2-4-10(7-9)11-5-6-16-14-12(19-11)13(15)17-8-18-14/h2-4,7-8H,5-6H2,1H3,(H3,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Plk1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376344
(CHEMBL262623)Show InChI InChI=1S/C13H13N5/c14-12-11-13(17-8-16-12)15-7-6-10(18-11)9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H3,14,15,16,17) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Akt1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human)) | BDBM50376345
(CHEMBL260620)Show InChI InChI=1S/C13H13ClN6/c14-8-3-1-7(2-4-8)9-5-6-17-12-10(18-9)11(15)19-13(16)20-12/h1-4H,5-6H2,(H5,15,16,17,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Pak4 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50376349
(CHEMBL405233)Show InChI InChI=1S/C14H15N5/c1-9-2-4-10(5-3-9)11-6-7-16-14-12(19-11)13(15)17-8-18-14/h2-5,8H,6-7H2,1H3,(H3,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Plk1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human)) | BDBM50376349
(CHEMBL405233)Show InChI InChI=1S/C14H15N5/c1-9-2-4-10(5-3-9)11-6-7-16-14-12(19-11)13(15)17-8-18-14/h2-5,8H,6-7H2,1H3,(H3,15,16,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Pak4 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376346
(CHEMBL259381)Show InChI InChI=1S/C13H13ClN6/c14-8-3-1-2-7(6-8)9-4-5-17-12-10(18-9)11(15)19-13(16)20-12/h1-3,6H,4-5H2,(H5,15,16,17,19,20) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Akt1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human)) | BDBM50376351
(CHEMBL259380)Show InChI InChI=1S/C13H14N6/c14-11-10-12(19-13(15)18-11)16-7-6-9(17-10)8-4-2-1-3-5-8/h1-5H,6-7H2,(H5,14,15,16,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Pak4 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50376346
(CHEMBL259381)Show InChI InChI=1S/C13H13ClN6/c14-8-3-1-2-7(6-8)9-4-5-17-12-10(18-9)11(15)19-13(16)20-12/h1-3,6H,4-5H2,(H5,15,16,17,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Plk1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50376345
(CHEMBL260620)Show InChI InChI=1S/C13H13ClN6/c14-8-3-1-7(2-4-8)9-5-6-17-12-10(18-9)11(15)19-13(16)20-12/h1-4H,5-6H2,(H5,15,16,17,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Plk1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human)) | BDBM50376350
(CHEMBL263902)Show InChI InChI=1S/C14H15N5/c1-9-3-2-4-10(7-9)11-5-6-16-14-12(19-11)13(15)17-8-18-14/h2-4,7-8H,5-6H2,1H3,(H3,15,16,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Pak4 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human)) | BDBM50376348
(CHEMBL407532)Show InChI InChI=1S/C13H12ClN5/c14-9-3-1-2-8(6-9)10-4-5-16-13-11(19-10)12(15)17-7-18-13/h1-3,6-7H,4-5H2,(H3,15,16,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Pak4 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376349
(CHEMBL405233)Show InChI InChI=1S/C14H15N5/c1-9-2-4-10(5-3-9)11-6-7-16-14-12(19-11)13(15)17-8-18-14/h2-5,8H,6-7H2,1H3,(H3,15,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Akt1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376348
(CHEMBL407532)Show InChI InChI=1S/C13H12ClN5/c14-9-3-1-2-8(6-9)10-4-5-16-13-11(19-10)12(15)17-7-18-13/h1-3,6-7H,4-5H2,(H3,15,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Akt1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376345
(CHEMBL260620)Show InChI InChI=1S/C13H13ClN6/c14-8-3-1-7(2-4-8)9-5-6-17-12-10(18-9)11(15)19-13(16)20-12/h1-4H,5-6H2,(H5,15,16,17,19,20) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Akt1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human)) | BDBM50376347
(CHEMBL407265)Show InChI InChI=1S/C13H12ClN5/c14-9-3-1-8(2-4-9)10-5-6-16-13-11(19-10)12(15)17-7-18-13/h1-4,7H,5-6H2,(H3,15,16,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Pak4 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human)) | BDBM50376346
(CHEMBL259381)Show InChI InChI=1S/C13H13ClN6/c14-8-3-1-2-7(6-8)9-4-5-17-12-10(18-9)11(15)19-13(16)20-12/h1-3,6H,4-5H2,(H5,15,16,17,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Pak4 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376347
(CHEMBL407265)Show InChI InChI=1S/C13H12ClN5/c14-9-3-1-8(2-4-9)10-5-6-16-13-11(19-10)12(15)17-7-18-13/h1-4,7H,5-6H2,(H3,15,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Akt1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50376347
(CHEMBL407265)Show InChI InChI=1S/C13H12ClN5/c14-9-3-1-8(2-4-9)10-5-6-16-13-11(19-10)12(15)17-7-18-13/h1-4,7H,5-6H2,(H3,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Plk1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human)) | BDBM50376344
(CHEMBL262623)Show InChI InChI=1S/C13H13N5/c14-12-11-13(17-8-16-12)15-7-6-10(18-11)9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H3,14,15,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Pak4 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376350
(CHEMBL263902)Show InChI InChI=1S/C14H15N5/c1-9-3-2-4-10(7-9)11-5-6-16-14-12(19-11)13(15)17-8-18-14/h2-4,7-8H,5-6H2,1H3,(H3,15,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Akt1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50376344
(CHEMBL262623)Show InChI InChI=1S/C13H13N5/c14-12-11-13(17-8-16-12)15-7-6-10(18-11)9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H3,14,15,16,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Plk1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50376348
(CHEMBL407532)Show InChI InChI=1S/C13H12ClN5/c14-9-3-1-2-8(6-9)10-4-5-16-13-11(19-10)12(15)17-7-18-13/h1-3,6-7H,4-5H2,(H3,15,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Plk1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50376351
(CHEMBL259380)Show InChI InChI=1S/C13H14N6/c14-11-10-12(19-13(15)18-11)16-7-6-9(17-10)8-4-2-1-3-5-8/h1-5H,6-7H2,(H5,14,15,16,18,19) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Akt1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human)) | BDBM50376351
(CHEMBL259380)Show InChI InChI=1S/C13H14N6/c14-11-10-12(19-13(15)18-11)16-7-6-9(17-10)8-4-2-1-3-5-8/h1-5H,6-7H2,(H5,14,15,16,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Plk1 |
Bioorg Med Chem Lett 18: 2691-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.021
BindingDB Entry DOI: 10.7270/Q2KP831H |
More data for this
Ligand-Target Pair | |
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