Affinity Data by PubMed id=18403056

PubMed code 18403056

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Macaca mulatta)	BDBM50013847 (CHEMBL312040 \| Etonitazene \| {2-[2-(4-Ethoxy-benzy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid UniChem Similars	Article PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor in rhesus monkey brain membrane in presence of Na+ ions				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Macaca mulatta)	BDBM50013847 (CHEMBL312040 \| Etonitazene \| {2-[2-(4-Ethoxy-benzy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid UniChem Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor in rhesus monkey brain membrane in absence of Na+ ions				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor in rat brain membrane				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor in rat brain membrane				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor in rat brain membrane				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to kappa opioid receptor in rat brain membrane				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor in rat brain membrane				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to kappa opioid receptor in rat brain membrane				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%