Found 10 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein O-GlcNAcase
(Homo sapiens (Human)) | BDBM50327038
((3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,...)Show SMILES CC1=N[C@H]2[C@H](O[C@H](CO)[C@@H](O)[C@@H]2O)S1 |r,t:1| Show InChI InChI=1S/C8H13NO4S/c1-3-9-5-7(12)6(11)4(2-10)13-8(5)14-3/h4-8,10-12H,2H2,1H3/t4-,5-,6-,7-,8-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of human OGA |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | |
Beta-N-acetylhexosaminidase
(Streptomyces plicatus) | BDBM50327038
((3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,...)Show SMILES CC1=N[C@H]2[C@H](O[C@H](CO)[C@@H](O)[C@@H]2O)S1 |r,t:1| Show InChI InChI=1S/C8H13NO4S/c1-3-9-5-7(12)6(11)4(2-10)13-8(5)14-3/h4-8,10-12H,2H2,1H3/t4-,5-,6-,7-,8-/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of Streptomyces plicatus N-acetyl-hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Beta-N-acetylhexosaminidase
(Streptomyces plicatus) | BDBM50377440
(CHEMBL253537)Show SMILES CC(=O)N[C@@H]1NC[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C8H16N2O4/c1-4(12)10-8-7(14)6(13)5(3-11)2-9-8/h5-9,11,13-14H,2-3H2,1H3,(H,10,12)/t5-,6+,7+,8+/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of Streptomyces plicatus N-acetyl-hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | |
Beta-N-acetylhexosaminidase
(Streptomyces plicatus) | BDBM50377445
(CHEMBL403756)Show SMILES CC1=N[C@H]2[C@H](O[C@H](CO)[C@H](O)[C@@H]2O)S1 |t:1| Show InChI InChI=1S/C8H13NO4S/c1-3-9-5-7(12)6(11)4(2-10)13-8(5)14-3/h4-8,10-12H,2H2,1H3/t4-,5-,6+,7-,8-/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of Streptomyces plicatus N-acetyl-hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | |
Beta-N-acetylhexosaminidase
(Streptomyces plicatus) | BDBM50377444
(CHEMBL404356)Show SMILES CC1=N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@]2(C)S1 |t:1| Show InChI InChI=1S/C9H15NO4S/c1-4-10-8-7(13)6(12)5(3-11)14-9(8,2)15-4/h5-8,11-13H,3H2,1-2H3/t5-,6-,7+,8-,9-/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of Streptomyces plicatus N-acetyl-hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | |
Beta-hexosaminidase subunit beta
(Homo sapiens (Human)) | BDBM50327038
((3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,...)Show SMILES CC1=N[C@H]2[C@H](O[C@H](CO)[C@@H](O)[C@@H]2O)S1 |r,t:1| Show InChI InChI=1S/C8H13NO4S/c1-3-9-5-7(12)6(11)4(2-10)13-8(5)14-3/h4-8,10-12H,2H2,1H3/t4-,5-,6-,7-,8-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of human beta hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Beta-hexosaminidase subunit beta
(Homo sapiens (Human)) | BDBM50377445
(CHEMBL403756)Show SMILES CC1=N[C@H]2[C@H](O[C@H](CO)[C@H](O)[C@@H]2O)S1 |t:1| Show InChI InChI=1S/C8H13NO4S/c1-3-9-5-7(12)6(11)4(2-10)13-8(5)14-3/h4-8,10-12H,2H2,1H3/t4-,5-,6+,7-,8-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 8.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of human beta hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | |
Beta-N-acetylhexosaminidase
(Streptomyces plicatus) | BDBM50377441
(CHEMBL404651)Show InChI InChI=1S/C8H11NO4S/c1-3-9-5-7(12)6(11)4(2-10)13-8(5)14-3/h4,6-7,10-12H,2H2,1H3/t4-,6+,7-/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.60E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of Streptomyces plicatus N-acetyl-hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | |
Beta-N-acetylhexosaminidase
(Streptomyces plicatus) | BDBM50377442
(CHEMBL255693)Show SMILES CC1=N[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@]2(CNC(=O)OC(C)(C)C)S1 |t:1| Show InChI InChI=1S/C14H24N2O6S/c1-7-16-11-10(19)9(18)8(5-17)21-14(11,23-7)6-15-12(20)22-13(2,3)4/h8-11,17-19H,5-6H2,1-4H3,(H,15,20)/t8-,9+,10+,11-,14-/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of Streptomyces plicatus N-acetyl-hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | |
Beta-N-acetylhexosaminidase
(Streptomyces plicatus) | BDBM50377443
(CHEMBL403748)Show SMILES CC1=N[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@]2(CN)S1 |t:1| Show InChI InChI=1S/C9H16N2O4S/c1-4-11-8-7(14)6(13)5(2-12)15-9(8,3-10)16-4/h5-8,12-14H,2-3,10H2,1H3/t5-,6+,7+,8-,9-/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description Inhibition of Streptomyces plicatus N-acetyl-hexosaminidase |
Bioorg Med Chem Lett 18: 2944-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.067 BindingDB Entry DOI: 10.7270/Q2GH9JVC |
More data for this Ligand-Target Pair | |