Found 40 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260798
(CHEMBL497961 | N-hydroxy-2,3-bis(4-iodophenylsulfo...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(I)cc1)NS(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C15H15I2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260826
(CHEMBL497761 | N-hydroxy-2,3-bis(4-methoxyphenylsu...)Show SMILES COc1ccc(cc1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1)C(=O)NO Show InChI InChI=1S/C17H21N3O8S2/c1-27-12-3-7-14(8-4-12)29(23,24)18-11-16(17(21)19-22)20-30(25,26)15-9-5-13(28-2)6-10-15/h3-10,16,18,20,22H,11H2,1-2H3,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260801
(2,3-bis(4-bromophenylsulfonamido)-N-hydroxypropana...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(Br)cc1)NS(=O)(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C15H15Br2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260802
(CHEMBL496717 | N-hydroxy-2,3-bis(phenylsulfonamido...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccccc1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H17N3O6S2/c19-15(17-20)14(18-26(23,24)13-9-5-2-6-10-13)11-16-25(21,22)12-7-3-1-4-8-12/h1-10,14,16,18,20H,11H2,(H,17,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 227 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260828
(2,3-bis(4-chlorophenylsulfonamido)-N-hydroxypropan...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(Cl)cc1)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H15Cl2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260828
(2,3-bis(4-chlorophenylsulfonamido)-N-hydroxypropan...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(Cl)cc1)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H15Cl2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 237 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260884
(2,3-bis(2,4-dimethoxyphenylsulfonamido)-N-hydroxyp...)Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1OC)C(=O)NO Show InChI InChI=1S/C19H25N3O10S2/c1-29-12-5-7-17(15(9-12)31-3)33(25,26)20-11-14(19(23)21-24)22-34(27,28)18-8-6-13(30-2)10-16(18)32-4/h5-10,14,20,22,24H,11H2,1-4H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 289 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50260826
(CHEMBL497761 | N-hydroxy-2,3-bis(4-methoxyphenylsu...)Show SMILES COc1ccc(cc1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1)C(=O)NO Show InChI InChI=1S/C17H21N3O8S2/c1-27-12-3-7-14(8-4-12)29(23,24)18-11-16(17(21)19-22)20-30(25,26)15-9-5-13(28-2)6-10-15/h3-10,16,18,20,22H,11H2,1-2H3,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 335 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP10 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50260802
(CHEMBL496717 | N-hydroxy-2,3-bis(phenylsulfonamido...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccccc1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H17N3O6S2/c19-15(17-20)14(18-26(23,24)13-9-5-2-6-10-13)11-16-25(21,22)12-7-3-1-4-8-12/h1-10,14,16,18,20H,11H2,(H,17,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 356 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP10 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260799
(CHEMBL497962 | N-hydroxy-2,3-bis(3-(trifluoromethy...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1cccc(c1)C(F)(F)F)NS(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C17H15F6N3O6S2/c18-16(19,20)10-3-1-5-12(7-10)33(29,30)24-9-14(15(27)25-28)26-34(31,32)13-6-2-4-11(8-13)17(21,22)23/h1-8,14,24,26,28H,9H2,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 602 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260826
(CHEMBL497761 | N-hydroxy-2,3-bis(4-methoxyphenylsu...)Show SMILES COc1ccc(cc1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1)C(=O)NO Show InChI InChI=1S/C17H21N3O8S2/c1-27-12-3-7-14(8-4-12)29(23,24)18-11-16(17(21)19-22)20-30(25,26)15-9-5-13(28-2)6-10-15/h3-10,16,18,20,22H,11H2,1-2H3,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 605 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260800
(2,3-bis(4-fluorophenylsulfonamido)-N-hydroxypropan...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(F)cc1)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C15H15F2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 625 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50260798
(CHEMBL497961 | N-hydroxy-2,3-bis(4-iodophenylsulfo...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(I)cc1)NS(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C15H15I2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP10 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260827
(CHEMBL497762 | N-hydroxy-2,3-bis(4-nitrophenylsulf...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(cc1)[N+]([O-])=O)NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H15N5O10S2/c21-15(17-22)14(18-32(29,30)13-7-3-11(4-8-13)20(25)26)9-16-31(27,28)12-5-1-10(2-6-12)19(23)24/h1-8,14,16,18,22H,9H2,(H,17,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260798
(CHEMBL497961 | N-hydroxy-2,3-bis(4-iodophenylsulfo...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(I)cc1)NS(=O)(=O)c1ccc(I)cc1 Show InChI InChI=1S/C15H15I2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260969
((S)-2,6-bis(4-bromophenylsulfonamido)-N-hydroxyhex...)Show SMILES ONC(=O)[C@H](CCCCNS(=O)(=O)c1ccc(Br)cc1)NS(=O)(=O)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C18H21Br2N3O6S2/c19-13-4-8-15(9-5-13)30(26,27)21-12-2-1-3-17(18(24)22-25)23-31(28,29)16-10-6-14(20)7-11-16/h4-11,17,21,23,25H,1-3,12H2,(H,22,24)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260800
(2,3-bis(4-fluorophenylsulfonamido)-N-hydroxypropan...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(F)cc1)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C15H15F2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260802
(CHEMBL496717 | N-hydroxy-2,3-bis(phenylsulfonamido...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccccc1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H17N3O6S2/c19-15(17-20)14(18-26(23,24)13-9-5-2-6-10-13)11-16-25(21,22)12-7-3-1-4-8-12/h1-10,14,16,18,20H,11H2,(H,17,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260886
((S)-N-hydroxy-2,5-bis(phenylsulfonamido)pentanamid...)Show SMILES ONC(=O)[C@H](CCCNS(=O)(=O)c1ccccc1)NS(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C17H21N3O6S2/c21-17(19-22)16(20-28(25,26)15-10-5-2-6-11-15)12-7-13-18-27(23,24)14-8-3-1-4-9-14/h1-6,8-11,16,18,20,22H,7,12-13H2,(H,19,21)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260968
((S)-2,6-bis(4-fluorophenylsulfonamido)-N-hydroxyhe...)Show SMILES ONC(=O)[C@H](CCCCNS(=O)(=O)c1ccc(F)cc1)NS(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C18H21F2N3O6S2/c19-13-4-8-15(9-5-13)30(26,27)21-12-2-1-3-17(18(24)22-25)23-31(28,29)16-10-6-14(20)7-11-16/h4-11,17,21,23,25H,1-3,12H2,(H,22,24)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260912
((S)-N-hydroxy-2,5-bis(4-methoxyphenylsulfonamido)p...)Show SMILES COc1ccc(cc1)S(=O)(=O)NCCC[C@H](NS(=O)(=O)c1ccc(OC)cc1)C(=O)NO |r| Show InChI InChI=1S/C19H25N3O8S2/c1-29-14-5-9-16(10-6-14)31(25,26)20-13-3-4-18(19(23)21-24)22-32(27,28)17-11-7-15(30-2)8-12-17/h5-12,18,20,22,24H,3-4,13H2,1-2H3,(H,21,23)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50260800
(2,3-bis(4-fluorophenylsulfonamido)-N-hydroxypropan...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(F)cc1)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C15H15F2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP10 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260885
(2,3-bis(1-(dimethylamino)naphthalene-5-sulfonamido...)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCC(NS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)NO Show InChI InChI=1S/C27H31N5O6S2/c1-31(2)23-13-5-11-20-18(23)9-7-15-25(20)39(35,36)28-17-22(27(33)29-34)30-40(37,38)26-16-8-10-19-21(26)12-6-14-24(19)32(3)4/h5-16,22,28,30,34H,17H2,1-4H3,(H,29,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260940
((S)-N-hydroxy-2,5-bis(4-iodophenylsulfonamido)pent...)Show SMILES ONC(=O)[C@H](CCCNS(=O)(=O)c1ccc(I)cc1)NS(=O)(=O)c1ccc(I)cc1 |r| Show InChI InChI=1S/C17H19I2N3O6S2/c18-12-3-7-14(8-4-12)29(25,26)20-11-1-2-16(17(23)21-24)22-30(27,28)15-9-5-13(19)6-10-15/h3-10,16,20,22,24H,1-2,11H2,(H,21,23)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260801
(2,3-bis(4-bromophenylsulfonamido)-N-hydroxypropana...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(Br)cc1)NS(=O)(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C15H15Br2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260829
(CHEMBL494615 | N-hydroxy-2,3-bis(2-(trifluoromethy...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccccc1C(F)(F)F)NS(=O)(=O)c1ccccc1C(F)(F)F Show InChI InChI=1S/C17H15F6N3O6S2/c18-16(19,20)10-5-1-3-7-13(10)33(29,30)24-9-12(15(27)25-28)26-34(31,32)14-8-4-2-6-11(14)17(21,22)23/h1-8,12,24,26,28H,9H2,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260827
(CHEMBL497762 | N-hydroxy-2,3-bis(4-nitrophenylsulf...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(cc1)[N+]([O-])=O)NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H15N5O10S2/c21-15(17-22)14(18-32(29,30)13-7-3-11(4-8-13)20(25)26)9-16-31(27,28)12-5-1-10(2-6-12)19(23)24/h1-8,14,16,18,22H,9H2,(H,17,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260913
((S)-N-hydroxy-2,5-bis(4-(trifluoromethyl)phenylsul...)Show SMILES ONC(=O)[C@H](CCCNS(=O)(=O)c1ccc(cc1)C(F)(F)F)NS(=O)(=O)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C19H19F6N3O6S2/c20-18(21,22)12-3-7-14(8-4-12)35(31,32)26-11-1-2-16(17(29)27-30)28-36(33,34)15-9-5-13(6-10-15)19(23,24)25/h3-10,16,26,28,30H,1-2,11H2,(H,27,29)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260754
(CHEMBL521881 | N-hydroxy-2,3-bis(4-(trifluoromethy...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(cc1)C(F)(F)F)NS(=O)(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H15F6N3O6S2/c18-16(19,20)10-1-5-12(6-2-10)33(29,30)24-9-14(15(27)25-28)26-34(31,32)13-7-3-11(4-8-13)17(21,22)23/h1-8,14,24,26,28H,9H2,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260883
(CHEMBL494643 | N-hydroxy-2,3-bis(perfluorophenylsu...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F Show InChI InChI=1S/C15H7F10N3O6S2/c16-3-5(18)9(22)13(10(23)6(3)19)35(31,32)26-1-2(15(29)27-30)28-36(33,34)14-11(24)7(20)4(17)8(21)12(14)25/h2,26,28,30H,1H2,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrilysin
(Homo sapiens (Human)) | BDBM50260754
(CHEMBL521881 | N-hydroxy-2,3-bis(4-(trifluoromethy...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(cc1)C(F)(F)F)NS(=O)(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H15F6N3O6S2/c18-16(19,20)10-1-5-12(6-2-10)33(29,30)24-9-14(15(27)25-28)26-34(31,32)13-7-3-11(4-8-13)17(21,22)23/h1-8,14,24,26,28H,9H2,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP7 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50260827
(CHEMBL497762 | N-hydroxy-2,3-bis(4-nitrophenylsulf...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(cc1)[N+]([O-])=O)NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H15N5O10S2/c21-15(17-22)14(18-32(29,30)13-7-3-11(4-8-13)20(25)26)9-16-31(27,28)12-5-1-10(2-6-12)19(23)24/h1-8,14,16,18,22H,9H2,(H,17,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP10 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50260754
(CHEMBL521881 | N-hydroxy-2,3-bis(4-(trifluoromethy...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(cc1)C(F)(F)F)NS(=O)(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H15F6N3O6S2/c18-16(19,20)10-1-5-12(6-2-10)33(29,30)24-9-14(15(27)25-28)26-34(31,32)13-7-3-11(4-8-13)17(21,22)23/h1-8,14,24,26,28H,9H2,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP10 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260884
(2,3-bis(2,4-dimethoxyphenylsulfonamido)-N-hydroxyp...)Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1OC)C(=O)NO Show InChI InChI=1S/C19H25N3O10S2/c1-29-12-5-7-17(15(9-12)31-3)33(25,26)20-11-14(19(23)21-24)22-34(27,28)18-8-6-13(30-2)10-16(18)32-4/h5-10,14,20,22,24H,11H2,1-4H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.24E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260885
(2,3-bis(1-(dimethylamino)naphthalene-5-sulfonamido...)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCC(NS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)NO Show InChI InChI=1S/C27H31N5O6S2/c1-31(2)23-13-5-11-20-18(23)9-7-15-25(20)39(35,36)28-17-22(27(33)29-34)30-40(37,38)26-16-8-10-19-21(26)12-6-14-24(19)32(3)4/h5-16,22,28,30,34H,17H2,1-4H3,(H,29,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260883
(CHEMBL494643 | N-hydroxy-2,3-bis(perfluorophenylsu...)Show SMILES ONC(=O)C(CNS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F Show InChI InChI=1S/C15H7F10N3O6S2/c16-3-5(18)9(22)13(10(23)6(3)19)35(31,32)26-1-2(15(29)27-30)28-36(33,34)14-11(24)7(20)4(17)8(21)12(14)25/h2,26,28,30H,1H2,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260940
((S)-N-hydroxy-2,5-bis(4-iodophenylsulfonamido)pent...)Show SMILES ONC(=O)[C@H](CCCNS(=O)(=O)c1ccc(I)cc1)NS(=O)(=O)c1ccc(I)cc1 |r| Show InChI InChI=1S/C17H19I2N3O6S2/c18-12-3-7-14(8-4-12)29(25,26)20-11-1-2-16(17(23)21-24)22-30(27,28)15-9-5-13(19)6-10-15/h3-10,16,20,22,24H,1-2,11H2,(H,21,23)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50260913
((S)-N-hydroxy-2,5-bis(4-(trifluoromethyl)phenylsul...)Show SMILES ONC(=O)[C@H](CCCNS(=O)(=O)c1ccc(cc1)C(F)(F)F)NS(=O)(=O)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C19H19F6N3O6S2/c20-18(21,22)12-3-7-14(8-4-12)35(31,32)26-11-1-2-16(17(29)27-30)28-36(33,34)15-9-5-13(6-10-15)19(23,24)25/h3-10,16,26,28,30H,1-2,11H2,(H,27,29)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50260913
((S)-N-hydroxy-2,5-bis(4-(trifluoromethyl)phenylsul...)Show SMILES ONC(=O)[C@H](CCCNS(=O)(=O)c1ccc(cc1)C(F)(F)F)NS(=O)(=O)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C19H19F6N3O6S2/c20-18(21,22)12-3-7-14(8-4-12)35(31,32)26-11-1-2-16(17(29)27-30)28-36(33,34)15-9-5-13(6-10-15)19(23,24)25/h3-10,16,26,28,30H,1-2,11H2,(H,27,29)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.37E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP10 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM50260884
(2,3-bis(2,4-dimethoxyphenylsulfonamido)-N-hydroxyp...)Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1OC)C(=O)NO Show InChI InChI=1S/C19H25N3O10S2/c1-29-12-5-7-17(15(9-12)31-3)33(25,26)20-11-14(19(23)21-24)22-34(27,28)18-8-6-13(30-2)10-16(18)32-4/h5-10,14,20,22,24H,11H2,1-4H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.72E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP10 |
Bioorg Med Chem Lett 18: 3333-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R |
More data for this
Ligand-Target Pair | |
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