Affinity Data by PubMed id=1847432

PubMed code 1847432

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor mu using [3H]-DAGO as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008980 (4-(Phenyl-propionyl-amino)-1-(2-pyrazol-1-yl-ethyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008982 (CHEMBL168723 \| N-[4-Methoxymethyl-1-(2-pyrazol-1-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM83450 (ALFENTANIL \| Alfentanil hydrochloride \| MLS0023206...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor delta using [3DPDPE] as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50008980 (4-(Phenyl-propionyl-amino)-1-(2-pyrazol-1-yl-ethyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	809	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor delta using [3H]-DPDPE) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008983 (1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50008981 (CHEMBL169587 \| N-{1-[2-(1,3-Dioxo-1,3-dihydro-isoi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor mu using [3H]-DAGO) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50008982 (CHEMBL168723 \| N-[4-Methoxymethyl-1-(2-pyrazol-1-y...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor delta using [3H]-DPDPE) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor kappa using [3H]-EKC as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM83450 (ALFENTANIL \| Alfentanil hydrochloride \| MLS0023206...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor kappa using [3H]-EKC) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008981 (CHEMBL169587 \| N-{1-[2-(1,3-Dioxo-1,3-dihydro-isoi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor kappa using [3H]-EKC) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008983 (1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Anaquest, Inc. Curated by ChEMBL					Assay Description In vitro binding activity against opioid receptor kappa using [3H]-EKC) as radioligand				J Med Chem 34: 827-41 (1991) BindingDB Entry DOI: 10.7270/Q2TQ60H9
Anaquest, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%