Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM20608 (4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 10.3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Kyushu University | Assay Description The receptor-binding assay was conducted using [3H]4-hydroxytamoxifen (4-OHT) as the radioligand. To estimate the binding affinity, the IC50 values (... | Biochem Biophys Res Commun 373: 408-13 (2008) Article DOI: 10.1016/j.bbrc.2008.06.050 BindingDB Entry DOI: 10.7270/Q22R3Q0N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM29608 (Bisphenol A (BPA) | Diphenylolpropane | US9688816,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 13.1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Kyushu University | Assay Description The receptor-binding assay was conducted using [3H]4-hydroxytamoxifen (4-OHT) as the radioligand. To estimate the binding affinity, the IC50 values (... | Biochem Biophys Res Commun 373: 408-13 (2008) Article DOI: 10.1016/j.bbrc.2008.06.050 BindingDB Entry DOI: 10.7270/Q22R3Q0N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM29609 (4-alpha-Cumylphenol | 4-cumylphenol | US9688816, B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 13.9 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Kyushu University | Assay Description The receptor-binding assay was conducted using [3H]4-hydroxytamoxifen (4-OHT) as the radioligand. To estimate the binding affinity, the IC50 values (... | Biochem Biophys Res Commun 373: 408-13 (2008) Article DOI: 10.1016/j.bbrc.2008.06.050 BindingDB Entry DOI: 10.7270/Q22R3Q0N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM29610 (2,2-Diphenylpropane) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Kyushu University | Assay Description The receptor-binding assay was conducted using [3H]4-hydroxytamoxifen (4-OHT) as the radioligand. To estimate the binding affinity, the IC50 values (... | Biochem Biophys Res Commun 373: 408-13 (2008) Article DOI: 10.1016/j.bbrc.2008.06.050 BindingDB Entry DOI: 10.7270/Q22R3Q0N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |