Found 48 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50160672
(4-((R)-Ethylamino)-6-(3-methoxy-propyl)-7,7-dioxo-...)Show SMILES CCNC1CC(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O Show InChI InChI=1S/C13H22N2O5S3/c1-3-15-11-7-9(5-4-6-20-2)22(16,17)13-10(11)8-12(21-13)23(14,18)19/h8-9,11,15H,3-7H2,1-2H3,(H2,14,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50160672
(4-((R)-Ethylamino)-6-(3-methoxy-propyl)-7,7-dioxo-...)Show SMILES CCNC1CC(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O Show InChI InChI=1S/C13H22N2O5S3/c1-3-15-11-7-9(5-4-6-20-2)22(16,17)13-10(11)8-12(21-13)23(14,18)19/h8-9,11,15H,3-7H2,1-2H3,(H2,14,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | 
3D Structure (docked) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
PC cid
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| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10890
(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12 Show InChI InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
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| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50094370
(CHEMBL22821 | Sulfonamide, 5)Show SMILES CCNC1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O Show InChI InChI=1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
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| Article
PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
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MMDB
PC cid
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| PDB
Article
PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10882
(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)Show InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
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MMDB
PC cid
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PDB
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| MMDB
PDB
Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50094370
(CHEMBL22821 | Sulfonamide, 5)Show SMILES CCNC1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O Show InChI InChI=1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM91708
(Sulfonamide, 8)Show InChI InChI=1S/C14H17NO5S/c15-21(17,18)20-9-6-7-11-10-4-2-1-3-5-12(10)14(16)19-13(11)8-9/h6-8,10,12H,1-5H2,(H2,15,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
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Similars
| DrugBank
MMDB
PDB
Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
PC cid
PC sid
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| PDB
Article
PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10890
(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12 Show InChI InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
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PDB
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| Article
PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM91708
(Sulfonamide, 8)Show InChI InChI=1S/C14H17NO5S/c15-21(17,18)20-9-6-7-11-10-4-2-1-3-5-12(10)14(16)19-13(11)8-9/h6-8,10,12H,1-5H2,(H2,15,17,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM91712
(Sulfonamide, 14)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2nnc(s2)S(N)(=O)=O)s1 Show InChI InChI=1S/C16H14N8O8S6/c17-35(25,26)15-21-19-13(33-15)23-37(29,30)11-5-1-9(2-6-11)10-3-7-12(8-4-10)38(31,32)24-14-20-22-16(34-14)36(18,27)28/h1-8H,(H,19,23)(H,20,24)(H2,17,25,26)(H2,18,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10882
(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)Show InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
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MCE
MMDB
PC cid
PC sid
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| Article
PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM91710
(Sulfonamide, 12)Show SMILES NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C28H30N4O8S4/c29-41(33,34)25-9-1-21(2-10-25)17-19-31-43(37,38)27-13-5-23(6-14-27)24-7-15-28(16-8-24)44(39,40)32-20-18-22-3-11-26(12-4-22)42(30,35)36/h1-16,31-32H,17-20H2,(H2,29,33,34)(H2,30,35,36) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10890
(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12 Show InChI InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
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| Article
PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10882
(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)Show InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
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MCE
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PC cid
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| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
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MCE
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PC cid
PC sid
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| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
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| Article
PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10890
(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12 Show InChI InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
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| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10882
(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)Show InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) | PDB
MMDB
NCI pathway
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| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM91708
(Sulfonamide, 8)Show InChI InChI=1S/C14H17NO5S/c15-21(17,18)20-9-6-7-11-10-4-2-1-3-5-12(10)14(16)19-13(11)8-9/h6-8,10,12H,1-5H2,(H2,15,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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| Article
PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM91712
(Sulfonamide, 14)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2nnc(s2)S(N)(=O)=O)s1 Show InChI InChI=1S/C16H14N8O8S6/c17-35(25,26)15-21-19-13(33-15)23-37(29,30)11-5-1-9(2-6-11)10-3-7-12(8-4-10)38(31,32)24-14-20-22-16(34-14)36(18,27)28/h1-8H,(H,19,23)(H,20,24)(H2,17,25,26)(H2,18,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50160672
(4-((R)-Ethylamino)-6-(3-methoxy-propyl)-7,7-dioxo-...)Show SMILES CCNC1CC(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O Show InChI InChI=1S/C13H22N2O5S3/c1-3-15-11-7-9(5-4-6-20-2)22(16,17)13-10(11)8-12(21-13)23(14,18)19/h8-9,11,15H,3-7H2,1-2H3,(H2,14,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10883
(4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...)Show InChI InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) | PDB
MMDB
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PDB
Article
PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM91710
(Sulfonamide, 12)Show SMILES NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C28H30N4O8S4/c29-41(33,34)25-9-1-21(2-10-25)17-19-31-43(37,38)27-13-5-23(6-14-27)24-7-15-28(16-8-24)44(39,40)32-20-18-22-3-11-26(12-4-22)42(30,35)36/h1-16,31-32H,17-20H2,(H2,29,33,34)(H2,30,35,36) | PDB
MMDB
Reactome pathway
KEGG
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| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | PDB
MMDB
NCI pathway
Reactome pathway
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| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10883
(4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...)Show InChI InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) | PDB
MMDB
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| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10883
(4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...)Show InChI InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) | PDB
MMDB
NCI pathway
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KEGG
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| Article
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| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50094370
(CHEMBL22821 | Sulfonamide, 5)Show SMILES CCNC1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O Show InChI InChI=1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8?/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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| 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM91709
(Sulfonamide, 11)Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C24H22N4O8S4/c25-37(29,30)21-13-5-19(6-14-21)27-39(33,34)23-9-1-17(2-10-23)18-3-11-24(12-4-18)40(35,36)28-20-7-15-22(16-8-20)38(26,31)32/h1-16,27-28H,(H2,25,29,30)(H2,26,31,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM91709
(Sulfonamide, 11)Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C24H22N4O8S4/c25-37(29,30)21-13-5-19(6-14-21)27-39(33,34)23-9-1-17(2-10-23)18-3-11-24(12-4-18)40(35,36)28-20-7-15-22(16-8-20)38(26,31)32/h1-16,27-28H,(H2,25,29,30)(H2,26,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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| PC cid
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| 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM91711
(Sulfonamide, 13)Show SMILES NS(=O)(=O)c1cc(c(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2cc(Cl)c(cc2S(N)(=O)=O)S(N)(=O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C24H22Cl2N6O12S6/c25-17-9-19(23(47(29,37)38)11-21(17)45(27,33)34)31-49(41,42)15-5-1-13(2-6-15)14-3-7-16(8-4-14)50(43,44)32-20-10-18(26)22(46(28,35)36)12-24(20)48(30,39)40/h1-12,31-32H,(H2,27,33,34)(H2,28,35,36)(H2,29,37,38)(H2,30,39,40) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM91711
(Sulfonamide, 13)Show SMILES NS(=O)(=O)c1cc(c(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2cc(Cl)c(cc2S(N)(=O)=O)S(N)(=O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C24H22Cl2N6O12S6/c25-17-9-19(23(47(29,37)38)11-21(17)45(27,33)34)31-49(41,42)15-5-1-13(2-6-15)14-3-7-16(8-4-14)50(43,44)32-20-10-18(26)22(46(28,35)36)12-24(20)48(30,39)40/h1-12,31-32H,(H2,27,33,34)(H2,28,35,36)(H2,29,37,38)(H2,30,39,40) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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GoogleScholar
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| PC cid
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UniChem
| Article
PubMed
| 129 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM91709
(Sulfonamide, 11)Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C24H22N4O8S4/c25-37(29,30)21-13-5-19(6-14-21)27-39(33,34)23-9-1-17(2-10-23)18-3-11-24(12-4-18)40(35,36)28-20-7-15-22(16-8-20)38(26,31)32/h1-16,27-28H,(H2,25,29,30)(H2,26,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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| PC cid
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Similars
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PubMed
| 145 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM91712
(Sulfonamide, 14)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2nnc(s2)S(N)(=O)=O)s1 Show InChI InChI=1S/C16H14N8O8S6/c17-35(25,26)15-21-19-13(33-15)23-37(29,30)11-5-1-9(2-6-11)10-3-7-12(8-4-10)38(31,32)24-14-20-22-16(34-14)36(18,27)28/h1-8H,(H,19,23)(H,20,24)(H2,17,25,26)(H2,18,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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| PC cid
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PubMed
| 154 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM91710
(Sulfonamide, 12)Show SMILES NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C28H30N4O8S4/c29-41(33,34)25-9-1-21(2-10-25)17-19-31-43(37,38)27-13-5-23(6-14-27)24-7-15-28(16-8-24)44(39,40)32-20-18-22-3-11-26(12-4-22)42(30,35)36/h1-16,31-32H,17-20H2,(H2,29,33,34)(H2,30,35,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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| PC cid
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Similars
| Article
PubMed
| 213 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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CHEMBL
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| DrugBank
PDB
Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM91711
(Sulfonamide, 13)Show SMILES NS(=O)(=O)c1cc(c(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2cc(Cl)c(cc2S(N)(=O)=O)S(N)(=O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C24H22Cl2N6O12S6/c25-17-9-19(23(47(29,37)38)11-21(17)45(27,33)34)31-49(41,42)15-5-1-13(2-6-15)14-3-7-16(8-4-14)50(43,44)32-20-10-18(26)22(46(28,35)36)12-24(20)48(30,39)40/h1-12,31-32H,(H2,27,33,34)(H2,28,35,36)(H2,29,37,38)(H2,30,39,40) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 362 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM91710
(Sulfonamide, 12)Show SMILES NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)NCCc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C28H30N4O8S4/c29-41(33,34)25-9-1-21(2-10-25)17-19-31-43(37,38)27-13-5-23(6-14-27)24-7-15-28(16-8-24)44(39,40)32-20-18-22-3-11-26(12-4-22)42(30,35)36/h1-16,31-32H,17-20H2,(H2,29,33,34)(H2,30,35,36) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 604 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM91709
(Sulfonamide, 11)Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1 Show InChI InChI=1S/C24H22N4O8S4/c25-37(29,30)21-13-5-19(6-14-21)27-39(33,34)23-9-1-17(2-10-23)18-3-11-24(12-4-18)40(35,36)28-20-7-15-22(16-8-20)38(26,31)32/h1-16,27-28H,(H2,25,29,30)(H2,26,31,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 675 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM91712
(Sulfonamide, 14)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2nnc(s2)S(N)(=O)=O)s1 Show InChI InChI=1S/C16H14N8O8S6/c17-35(25,26)15-21-19-13(33-15)23-37(29,30)11-5-1-9(2-6-11)10-3-7-12(8-4-10)38(31,32)24-14-20-22-16(34-14)36(18,27)28/h1-8H,(H,19,23)(H,20,24)(H2,17,25,26)(H2,18,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 693 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10883
(4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...)Show InChI InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
| DrugBank
Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM91711
(Sulfonamide, 13)Show SMILES NS(=O)(=O)c1cc(c(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2cc(Cl)c(cc2S(N)(=O)=O)S(N)(=O)=O)cc1Cl)S(N)(=O)=O Show InChI InChI=1S/C24H22Cl2N6O12S6/c25-17-9-19(23(47(29,37)38)11-21(17)45(27,33)34)31-49(41,42)15-5-1-13(2-6-15)14-3-7-16(8-4-14)50(43,44)32-20-10-18(26)22(46(28,35)36)12-24(20)48(30,39)40/h1-12,31-32H,(H2,27,33,34)(H2,28,35,36)(H2,29,37,38)(H2,30,39,40) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM91708
(Sulfonamide, 8)Show InChI InChI=1S/C14H17NO5S/c15-21(17,18)20-9-6-7-11-10-4-2-1-3-5-12(10)14(16)19-13(11)8-9/h6-8,10,12H,1-5H2,(H2,15,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50160672
(4-((R)-Ethylamino)-6-(3-methoxy-propyl)-7,7-dioxo-...)Show SMILES CCNC1CC(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O Show InChI InChI=1S/C13H22N2O5S3/c1-3-15-11-7-9(5-4-6-20-2)22(16,17)13-10(11)8-12(21-13)23(14,18)19/h8-9,11,15H,3-7H2,1-2H3,(H2,14,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50094370
(CHEMBL22821 | Sulfonamide, 5)Show SMILES CCNC1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O Show InChI InChI=1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8?/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Egyptian Petroleum Research Institute
| Assay Description
Inhibition assay using carbonic anhydrases. |
J Enzyme Inhib Med Chem 24: 499-505 (2009)
Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC |
More data for this
Ligand-Target Pair | |
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