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PubMed code 18637671

Compile data set for download or QSAR
Found 21 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM21864
PNG
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3|
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
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 7.44n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50262557
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCn1c23 |r|
Show InChI InChI=1S/C28H28N2O3/c31-20-7-6-17-12-21-28(32)13-19-18-3-1-2-16-8-10-30(23(16)18)24(19)26-27(28,22(17)25(20)33-26)9-11-29(21)14-15-4-5-15/h1-3,6-7,15,21,26,31-32H,4-5,8-14H2/t21-,26+,27+,28-/m1/s1
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 7.99n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM21864
PNG
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3|
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
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 12.7n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50244419
PNG
((4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCn1c23 |r|
Show InChI InChI=1S/C29H30N2O3/c32-21-9-8-18-13-22-29(33)14-20-19-5-1-3-17-4-2-11-31(24(17)19)25(20)27-28(29,23(18)26(21)34-27)10-12-30(22)15-16-6-7-16/h1,3,5,8-9,16,22,27,32-33H,2,4,6-7,10-15H2/t22-,27+,28+,29-/m1/s1
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 15.1n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50262557
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCn1c23 |r|
Show InChI InChI=1S/C28H28N2O3/c31-20-7-6-17-12-21-28(32)13-19-18-3-1-2-16-8-10-30(23(16)18)24(19)26-27(28,22(17)25(20)33-26)9-11-29(21)14-15-4-5-15/h1-3,6-7,15,21,26,31-32H,4-5,8-14H2/t21-,26+,27+,28-/m1/s1
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 23.2n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM21864
PNG
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3|
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
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 27n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Binding affinity to guinea pig mu opioid receptor

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM21864
PNG
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3|
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
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 30.4n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Binding affinity to guinea pig kappa opioid receptor

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50261726
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCCn1c23 |r|
Show InChI InChI=1S/C30H32N2O3/c33-22-10-9-19-14-23-30(34)15-21-20-6-3-5-18-4-1-2-12-32(25(18)20)26(21)28-29(30,24(19)27(22)35-28)11-13-31(23)16-17-7-8-17/h3,5-6,9-10,17,23,28,33-34H,1-2,4,7-8,11-16H2/t23-,28+,29+,30-/m1/s1
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 40n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50261791
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2c4CCCCc4ccc2c1C[C@@]35O |r|
Show InChI InChI=1S/C30H32N2O3/c33-22-10-8-18-13-23-30(34)14-21-20-9-7-17-3-1-2-4-19(17)25(20)31-26(21)28-29(30,24(18)27(22)35-28)11-12-32(23)15-16-5-6-16/h7-10,16,23,28,31,33-34H,1-6,11-15H2/t23-,28+,29+,30-/m1/s1
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 52n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50244419
PNG
((4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCn1c23 |r|
Show InChI InChI=1S/C29H30N2O3/c32-21-9-8-18-13-22-29(33)14-20-19-5-1-3-17-4-2-11-31(24(17)19)25(20)27-28(29,23(18)26(21)34-27)10-12-30(22)15-16-6-7-16/h1,3,5,8-9,16,22,27,32-33H,2,4,6-7,10-15H2/t22-,27+,28+,29-/m1/s1
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 60.6n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50261726
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCCn1c23 |r|
Show InChI InChI=1S/C30H32N2O3/c33-22-10-9-19-14-23-30(34)15-21-20-6-3-5-18-4-1-2-12-32(25(18)20)26(21)28-29(30,24(19)27(22)35-28)11-13-31(23)16-17-7-8-17/h3,5-6,9-10,17,23,28,33-34H,1-2,4,7-8,11-16H2/t23-,28+,29+,30-/m1/s1
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 113n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50261791
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2c4CCCCc4ccc2c1C[C@@]35O |r|
Show InChI InChI=1S/C30H32N2O3/c33-22-10-8-18-13-23-30(34)14-21-20-9-7-17-3-1-2-4-19(17)25(20)31-26(21)28-29(30,24(18)27(22)35-28)11-12-32(23)15-16-5-6-16/h7-10,16,23,28,31,33-34H,1-6,11-15H2/t23-,28+,29+,30-/m1/s1
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 200n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50262499
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O |r|
Show InChI InChI=1S/C27H28N2O3/c1-31-20-9-8-16-12-21-27(30)13-18-17-4-2-3-5-19(17)28-23(18)25-26(27,22(16)24(20)32-25)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,28,30H,6-7,10-14H2,1H3/t21-,25+,26+,27-/m1/s1
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 2.51E+3n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Binding affinity to guinea pig mu opioid receptor

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50245093
PNG
((5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro...)
Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCn1c23 |r|
Show InChI InChI=1S/C30H32N2O3/c1-34-22-10-9-19-14-23-30(33)15-21-20-6-2-4-18-5-3-12-32(25(18)20)26(21)28-29(30,24(19)27(22)35-28)11-13-31(23)16-17-7-8-17/h2,4,6,9-10,17,23,28,33H,3,5,7-8,11-16H2,1H3/t23-,28+,29+,30-/m1/s1
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 3.29E+3n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50261727
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCCn1c23 |r|
Show InChI InChI=1S/C31H34N2O3/c1-35-23-11-10-20-15-24-31(34)16-22-21-7-4-6-19-5-2-3-13-33(26(19)21)27(22)29-30(31,25(20)28(23)36-29)12-14-32(24)17-18-8-9-18/h4,6-7,10-11,18,24,29,34H,2-3,5,8-9,12-17H2,1H3/t24-,29+,30+,31-/m1/s1
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 3.34E+3n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50245093
PNG
((5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro...)
Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCn1c23 |r|
Show InChI InChI=1S/C30H32N2O3/c1-34-22-10-9-19-14-23-30(33)15-21-20-6-2-4-18-5-3-12-32(25(18)20)26(21)28-29(30,24(19)27(22)35-28)11-13-31(23)16-17-7-8-17/h2,4,6,9-10,17,23,28,33H,3,5,7-8,11-16H2,1H3/t23-,28+,29+,30-/m1/s1
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>3.67E+3n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50261727
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCCn1c23 |r|
Show InChI InChI=1S/C31H34N2O3/c1-35-23-11-10-20-15-24-31(34)16-22-21-7-4-6-19-5-2-3-13-33(26(19)21)27(22)29-30(31,25(20)28(23)36-29)12-14-32(24)17-18-8-9-18/h4,6-7,10-11,18,24,29,34H,2-3,5,8-9,12-17H2,1H3/t24-,29+,30+,31-/m1/s1
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>3.67E+3n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50262556
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES CCn1c2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2cccc(C)c12)ccc4OC |r|
Show InChI InChI=1S/C30H34N2O3/c1-4-32-25-17(2)6-5-7-20(25)21-15-30(33)23-14-19-10-11-22(34-3)27-24(19)29(30,28(35-27)26(21)32)12-13-31(23)16-18-8-9-18/h5-7,10-11,18,23,28,33H,4,8-9,12-16H2,1-3H3/t23-,28+,29+,30-/m1/s1
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>3.67E+3n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50262499
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O |r|
Show InChI InChI=1S/C27H28N2O3/c1-31-20-9-8-16-12-21-27(30)13-18-17-4-2-3-5-19(17)28-23(18)25-26(27,22(16)24(20)32-25)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,28,30H,6-7,10-14H2,1H3/t21-,25+,26+,27-/m1/s1
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 3.91E+3n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Binding affinity to guinea pig kappa opioid receptor

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50262556
PNG
((5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro...)
Show SMILES CCn1c2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2cccc(C)c12)ccc4OC |r|
Show InChI InChI=1S/C30H34N2O3/c1-4-32-25-17(2)6-5-7-20(25)21-15-30(33)23-14-19-10-11-22(34-3)27-24(19)29(30,28(35-27)26(21)32)12-13-31(23)16-18-8-9-18/h5-7,10-11,18,23,28,33H,4,8-9,12-16H2,1-3H3/t23-,28+,29+,30-/m1/s1
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 4.65E+3n/an/an/an/an/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from kappa opioid receptor in Hartley guinea pig brain membrane

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM21015
PNG
((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO
Show InChI InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1
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n/an/an/an/a 1.70n/an/an/an/a



Toray Industries, Inc

Curated by ChEMBL


Assay Description
Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding

J Med Chem 51: 4404-11 (2008)


Article DOI: 10.1021/jm701440h
BindingDB Entry DOI: 10.7270/Q2PG1SN2
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%