Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24949 (3-(2-hydroxyethyl)-20-(propan-2-yloxy)-3,13-diazah...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24942 (CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24952 (20-(cyclopentyloxy)-3-(2-hydroxyethyl)-3,13-diazah...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24947 (3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24942 (CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24949 (3-(2-hydroxyethyl)-20-(propan-2-yloxy)-3,13-diazah...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24944 (20-(propan-2-yloxy)-3,13-diazahexacyclo[14.8.0.0^{...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24948 (3-(3-hydroxypropyl)-20-methoxy-3,13-diazahexacyclo...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 87 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24948 (3-(3-hydroxypropyl)-20-methoxy-3,13-diazahexacyclo...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 101 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24947 (3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 103 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24944 (20-(propan-2-yloxy)-3,13-diazahexacyclo[14.8.0.0^{...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 159 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24943 (20-methoxy-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 188 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24943 (20-methoxy-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 274 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM14178 (12,13-dihydro-6H,7H,14H-naphthyl-[3,4-a]pyrrolo[3,...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 724 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24946 (3-(2-hydroxyethyl)-3,13-diazahexacyclo[14.8.0.0^{2...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM24949 (3-(2-hydroxyethyl)-20-(propan-2-yloxy)-3,13-diazah...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description Compounds were evaluated for their ability to inhibit the kinase activity of TrkA using an ELISA-based assay. The 96-well microtiter plate is coated ... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM14178 (12,13-dihydro-6H,7H,14H-naphthyl-[3,4-a]pyrrolo[3,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM24947 (3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description Compounds were evaluated for their ability to inhibit the kinase activity of TrkA using an ELISA-based assay. The 96-well microtiter plate is coated ... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 10 (Homo sapiens (Human)) | BDBM24947 (3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 10 (Homo sapiens (Human)) | BDBM24949 (3-(2-hydroxyethyl)-20-(propan-2-yloxy)-3,13-diazah...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM24949 (3-(2-hydroxyethyl)-20-(propan-2-yloxy)-3,13-diazah...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description Compounds were evaluated for their ability to inhibit the kinase activity using an ELISA-based assay. The 96-well microtiter plate is coated with sub... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM24947 (3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description Compounds were evaluated for their ability to inhibit the kinase activity using an ELISA-based assay. The 96-well microtiter plate is coated with sub... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24955 (3-(2-hydroxyethyl)-20-(2-methoxyethoxy)-3,13-diaza...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24957 (20-(2-hydroxyethoxy)-3-(2-hydroxyethyl)-3,13-diaza...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24950 (20-hydroxy-3-(2-hydroxyethyl)-3,13-diazahexacyclo[...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24958 (2-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24957 (20-(2-hydroxyethoxy)-3-(2-hydroxyethyl)-3,13-diaza...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24956 (20-[2-(benzyloxy)ethoxy]-3-(2-hydroxyethyl)-3,13-d...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24952 (20-(cyclopentyloxy)-3-(2-hydroxyethyl)-3,13-diazah...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24956 (20-[2-(benzyloxy)ethoxy]-3-(2-hydroxyethyl)-3,13-d...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24953 (20-(cyclohexyloxy)-3-(2-hydroxyethyl)-3,13-diazahe...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24946 (3-(2-hydroxyethyl)-3,13-diazahexacyclo[14.8.0.0^{2...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24958 (2-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24954 (3-(2-hydroxyethyl)-20-(pyridin-2-ylmethoxy)-3,13-d...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24951 (20-(cyclopropylmethoxy)-3-(2-hydroxyethyl)-3,13-di...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24954 (3-(2-hydroxyethyl)-20-(pyridin-2-ylmethoxy)-3,13-d...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24953 (20-(cyclohexyloxy)-3-(2-hydroxyethyl)-3,13-diazahe...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24945 (20-hydroxy-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24959 (4-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24959 (4-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24955 (3-(2-hydroxyethyl)-20-(2-methoxyethoxy)-3,13-diaza...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24950 (20-hydroxy-3-(2-hydroxyethyl)-3,13-diazahexacyclo[...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human)) | BDBM24945 (20-hydroxy-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 37 |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM24951 (20-(cyclopropylmethoxy)-3-(2-hydroxyethyl)-3,13-di...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon | Assay Description The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera... | J Med Chem 51: 5680-9 (2008) Article DOI: 10.1021/jm8005838 BindingDB Entry DOI: 10.7270/Q2TH8K09 | |||||||||||
More data for this Ligand-Target Pair |