Found 114 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50145415
(1-(2-chloro-2-phenylethyl)-N,N-diethyl-6-(methylth...)Show InChI InChI=1S/C18H22ClN5S/c1-4-23(5-2)16-14-11-20-24(17(14)22-18(21-16)25-3)12-15(19)13-9-7-6-8-10-13/h6-11,15H,4-5,12H2,1-3H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50145425
(1-(2-chloro-2-phenylethyl)-6-(ethylthio)-N-propyl-...)Show InChI InChI=1S/C18H22ClN5S/c1-3-10-20-16-14-11-21-24(17(14)23-18(22-16)25-4-2)12-15(19)13-8-6-5-7-9-13/h5-9,11,15H,3-4,10,12H2,1-2H3,(H,20,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50142882
(Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-ethylsulfanyl...)Show InChI InChI=1S/C19H24ClN5S/c1-3-5-11-21-17-15-12-22-25(18(15)24-19(23-17)26-4-2)13-16(20)14-9-7-6-8-10-14/h6-10,12,16H,3-5,11,13H2,1-2H3,(H,21,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50145411
(1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-propyl...)Show InChI InChI=1S/C17H20ClN5S/c1-3-9-19-15-13-10-20-23(16(13)22-17(21-15)24-2)11-14(18)12-7-5-4-6-8-12/h4-8,10,14H,3,9,11H2,1-2H3,(H,19,21,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183364
(1-(2-bromo-2-phenylethyl)-N-propyl-1H-pyrazolo[3,4...)Show InChI InChI=1S/C16H18BrN5/c1-2-8-18-15-13-9-21-22(16(13)20-11-19-15)10-14(17)12-6-4-3-5-7-12/h3-7,9,11,14H,2,8,10H2,1H3,(H,18,19,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50224368
(1-(2-chloro-2-phenylethyl)-N-(3-chlorophenyl)-6-(m...)Show SMILES CSc1nc(Nc2cccc(Cl)c2)c2cnn(CC(Cl)c3ccccc3)c2n1 Show InChI InChI=1S/C20H17Cl2N5S/c1-28-20-25-18(24-15-9-5-8-14(21)10-15)16-11-23-27(19(16)26-20)12-17(22)13-6-3-2-4-7-13/h2-11,17H,12H2,1H3,(H,24,25,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183338
(1-(2-bromo-2-phenylethyl)-4-(piperidin-1-yl)-1H-py...)Show InChI InChI=1S/C18H20BrN5/c19-16(14-7-3-1-4-8-14)12-24-18-15(11-22-24)17(20-13-21-18)23-9-5-2-6-10-23/h1,3-4,7-8,11,13,16H,2,5-6,9-10,12H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183345
(1-(2-bromo-2-phenylethyl)-N-(2-ethoxyethyl)-1H-pyr...)Show InChI InChI=1S/C17H20BrN5O/c1-2-24-9-8-19-16-14-10-22-23(17(14)21-12-20-16)11-15(18)13-6-4-3-5-7-13/h3-7,10,12,15H,2,8-9,11H2,1H3,(H,19,20,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413975
(CHEMBL472822)Show InChI InChI=1S/C17H20ClN5/c1-2-3-9-19-16-14-10-22-23(17(14)21-12-20-16)11-15(18)13-7-5-4-6-8-13/h4-8,10,12,15H,2-3,9,11H2,1H3,(H,19,20,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413973
(CHEMBL515760)Show InChI InChI=1S/C21H20ClN5/c22-19(17-9-5-2-6-10-17)14-27-21-18(13-26-27)20(24-15-25-21)23-12-11-16-7-3-1-4-8-16/h1-10,13,15,19H,11-12,14H2,(H,23,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50142889
(Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfany...)Show InChI InChI=1S/C18H22ClN5S/c1-3-4-10-20-16-14-11-21-24(17(14)23-18(22-16)25-2)12-15(19)13-8-6-5-7-9-13/h5-9,11,15H,3-4,10,12H2,1-2H3,(H,20,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414018
(CHEMBL515714)Show InChI InChI=1S/C17H18ClN5S/c1-24-17-21-15(20-12-7-8-12)13-9-19-23(16(13)22-17)10-14(18)11-5-3-2-4-6-11/h2-6,9,12,14H,7-8,10H2,1H3,(H,20,21,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183355
(2-(4-(benzylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-y...)Show InChI InChI=1S/C20H19N5O/c26-18(16-9-5-2-6-10-16)13-25-20-17(12-24-25)19(22-14-23-20)21-11-15-7-3-1-4-8-15/h1-10,12,14,18,26H,11,13H2,(H,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50142884
(1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-4-pip...)Show InChI InChI=1S/C19H22ClN5S/c1-26-19-22-17(24-10-6-3-7-11-24)15-12-21-25(18(15)23-19)13-16(20)14-8-4-2-5-9-14/h2,4-5,8-9,12,16H,3,6-7,10-11,13H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183347
(2-(4-(phenethylamino)-1H-pyrazolo[3,4-d]pyrimidin-...)Show InChI InChI=1S/C21H21N5O/c27-19(17-9-5-2-6-10-17)14-26-21-18(13-25-26)20(23-15-24-21)22-12-11-16-7-3-1-4-8-16/h1-10,13,15,19,27H,11-12,14H2,(H,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414017
(CHEMBL514928)Show InChI InChI=1S/C19H22ClN5/c20-17(14-7-3-1-4-8-14)12-25-19-16(11-23-25)18(21-13-22-19)24-15-9-5-2-6-10-15/h1,3-4,7-8,11,13,15,17H,2,5-6,9-10,12H2,(H,21,22,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50354486
(CHEMBL411043)Show InChI InChI=1S/C20H18ClN5/c21-18(16-9-5-2-6-10-16)13-26-20-17(12-25-26)19(23-14-24-20)22-11-15-7-3-1-4-8-15/h1-10,12,14,18H,11,13H2,(H,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183336
(1-(2-bromo-2-phenylethyl)-N-butyl-1H-pyrazolo[3,4-...)Show InChI InChI=1S/C17H20BrN5/c1-2-3-9-19-16-14-10-22-23(17(14)21-12-20-16)11-15(18)13-7-5-4-6-8-13/h4-8,10,12,15H,2-3,9,11H2,1H3,(H,19,20,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414016
(CHEMBL475366)Show InChI InChI=1S/C16H18ClN5/c1-2-8-18-15-13-9-21-22(16(13)20-11-19-15)10-14(17)12-6-4-3-5-7-12/h3-7,9,11,14H,2,8,10H2,1H3,(H,18,19,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183351
(1-(2-bromo-2-phenylethyl)-N-isopropyl-1H-pyrazolo[...)Show InChI InChI=1S/C16H18BrN5/c1-11(2)21-15-13-8-20-22(16(13)19-10-18-15)9-14(17)12-6-4-3-5-7-12/h3-8,10-11,14H,9H2,1-2H3,(H,18,19,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183342
(CHEMBL382153 | N-benzyl-1-(2-bromo-2-phenylethyl)-...)Show InChI InChI=1S/C20H18BrN5/c21-18(16-9-5-2-6-10-16)13-26-20-17(12-25-26)19(23-14-24-20)22-11-15-7-3-1-4-8-15/h1-10,12,14,18H,11,13H2,(H,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50142885
(Benzyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfan...)Show SMILES CSc1nc(NCc2ccccc2)c2cnn(CC(Cl)c3ccccc3)c2n1 Show InChI InChI=1S/C21H20ClN5S/c1-28-21-25-19(23-12-15-8-4-2-5-9-15)17-13-24-27(20(17)26-21)14-18(22)16-10-6-3-7-11-16/h2-11,13,18H,12,14H2,1H3,(H,23,25,26) | PDB
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PC sid
UniChem
Similars
| Article
PubMed
| 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414019
(CHEMBL471913)Show SMILES OC(=O)c1cnc2n(\C=C\c3ccccc3)ncc2c1NCc1ccccc1 Show InChI InChI=1S/C22H18N4O2/c27-22(28)19-14-24-21-18(20(19)23-13-17-9-5-2-6-10-17)15-25-26(21)12-11-16-7-3-1-4-8-16/h1-12,14-15H,13H2,(H,23,24)(H,27,28)/b12-11+ | PDB
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PC cid
PC sid
UniChem
| Article
PubMed
| 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50142890
(1-(2-Chloro-2-phenyl-ethyl)-6-ethylsulfanyl-4-morp...)Show InChI InChI=1S/C19H22ClN5OS/c1-2-27-19-22-17(24-8-10-26-11-9-24)15-12-21-25(18(15)23-19)13-16(20)14-6-4-3-5-7-14/h3-7,12,16H,2,8-11,13H2,1H3 | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413974
(CHEMBL475367)Show InChI InChI=1S/C17H20ClN5/c1-3-22(4-2)16-14-10-21-23(17(14)20-12-19-16)11-15(18)13-8-6-5-7-9-13/h5-10,12,15H,3-4,11H2,1-2H3 | PDB
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PC sid
UniChem
Similars
| Article
PubMed
| 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50142879
(1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-4-mor...)Show InChI InChI=1S/C18H20ClN5OS/c1-26-18-21-16(23-7-9-25-10-8-23)14-11-20-24(17(14)22-18)12-15(19)13-5-3-2-4-6-13/h2-6,11,15H,7-10,12H2,1H3 | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413976
(CHEMBL472959)Show InChI InChI=1S/C18H20ClN5/c19-16(14-7-3-1-4-8-14)12-24-18-15(11-22-24)17(20-13-21-18)23-9-5-2-6-10-23/h1,3-4,7-8,11,13,16H,2,5-6,9-10,12H2 | PDB
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UniChem
Similars
| Article
PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50145413
(1-(2-Chloro-2-phenyl-ethyl)-6-ethylsulfanyl-4-pipe...)Show InChI InChI=1S/C20H24ClN5S/c1-2-27-20-23-18(25-11-7-4-8-12-25)16-13-22-26(19(16)24-20)14-17(21)15-9-5-3-6-10-15/h3,5-6,9-10,13,17H,2,4,7-8,11-12,14H2,1H3 | PDB
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UniChem
Similars
| Article
PubMed
| 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50145423
(Benzyl-[1-(2-chloro-2-phenyl-ethyl)-6-ethylsulfany...)Show SMILES CCSc1nc(NCc2ccccc2)c2cnn(CC(Cl)c3ccccc3)c2n1 Show InChI InChI=1S/C22H22ClN5S/c1-2-29-22-26-20(24-13-16-9-5-3-6-10-16)18-14-25-28(21(18)27-22)15-19(23)17-11-7-4-8-12-17/h3-12,14,19H,2,13,15H2,1H3,(H,24,26,27) | PDB
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UniChem
Similars
| Article
PubMed
| 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50183352
(1-(2-bromo-2-phenylethyl)-4-(pyrrolidin-1-yl)-1H-p...)Show InChI InChI=1S/C17H18BrN5/c18-15(13-6-2-1-3-7-13)11-23-17-14(10-21-23)16(19-12-20-17)22-8-4-5-9-22/h1-3,6-7,10,12,15H,4-5,8-9,11H2 | PDB
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PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414010
(CHEMBL84945)Show InChI InChI=1S/C16H19N5O/c1-2-8-17-15-13-9-20-21(16(13)19-11-18-15)10-14(22)12-6-4-3-5-7-12/h3-7,9,11,14,22H,2,8,10H2,1H3,(H,17,18,19) | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413977
(CHEMBL473154)Show InChI InChI=1S/C19H22ClN5/c20-17(15-8-4-3-5-9-15)13-25-19-16(12-23-25)18(21-14-22-19)24-10-6-1-2-7-11-24/h3-5,8-9,12,14,17H,1-2,6-7,10-11,13H2 | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414011
(CHEMBL203650)Show InChI InChI=1S/C20H18FN5O/c21-16-8-6-14(7-9-16)10-22-19-17-11-25-26(20(17)24-13-23-19)12-18(27)15-4-2-1-3-5-15/h1-9,11,13,18,27H,10,12H2,(H,22,23,24) | PDB
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UniChem
Similars
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| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414020
(CHEMBL475190)Show InChI InChI=1S/C16H16ClN5/c17-14(11-4-2-1-3-5-11)9-22-16-13(8-20-22)15(18-10-19-16)21-12-6-7-12/h1-5,8,10,12,14H,6-7,9H2,(H,18,19,21) | PDB
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PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414006
(CHEMBL516062)Show SMILES CN(C)CCc1ccccc1-n1cc(-c2cccc(O)c2)c2c(N)ncnc12 Show InChI InChI=1S/C22H23N5O/c1-26(2)11-10-15-6-3-4-9-19(15)27-13-18(16-7-5-8-17(28)12-16)20-21(23)24-14-25-22(20)27/h3-9,12-14,28H,10-11H2,1-2H3,(H2,23,24,25) | PDB
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.316 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414005
(CHEMBL474998)Show SMILES Nc1ncnc2n(cc(-c3cccc(O)c3)c12)-c1ccc(OCCNCCO)cc1 Show InChI InChI=1S/C22H23N5O3/c23-21-20-19(15-2-1-3-17(29)12-15)13-27(22(20)26-14-25-21)16-4-6-18(7-5-16)30-11-9-24-8-10-28/h1-7,12-14,24,28-29H,8-11H2,(H2,23,25,26) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.316 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097979
(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)Show SMILES NC(=O)CN1CCC(CC1)n1cc(-c2cccc(O)c2)c2c(N)ncnc12 Show InChI InChI=1S/C19H22N6O2/c20-16(27)10-24-6-4-13(5-7-24)25-9-15(12-2-1-3-14(26)8-12)17-18(21)22-11-23-19(17)25/h1-3,8-9,11,13,26H,4-7,10H2,(H2,20,27)(H2,21,22,23) | PDB
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| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097967
(3-(4-amino-7-(1-(2-hydroxyethyl)piperidin-4-yl)-7H...)Show SMILES Nc1ncnc2n(cc(-c3cccc(O)c3)c12)C1CCN(CCO)CC1 Show InChI InChI=1S/C19H23N5O2/c20-18-17-16(13-2-1-3-15(26)10-13)11-24(19(17)22-12-21-18)14-4-6-23(7-5-14)8-9-25/h1-3,10-12,14,25-26H,4-9H2,(H2,20,21,22) | PDB
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PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097956
(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)Show InChI InChI=1S/C17H18N4O/c18-16-15-14(11-4-3-7-13(22)8-11)9-21(12-5-1-2-6-12)17(15)20-10-19-16/h3-4,7-10,12,22H,1-2,5-6H2,(H2,18,19,20) | PDB
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UniChem
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| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097971
(CHEMBL262276 | methyl 2-(4-(4-amino-5-(3-hydroxyph...)Show SMILES COC(=O)CN1CCC(CC1)n1cc(-c2cccc(O)c2)c2c(N)ncnc12 Show InChI InChI=1S/C20H23N5O3/c1-28-17(27)11-24-7-5-14(6-8-24)25-10-16(13-3-2-4-15(26)9-13)18-19(21)22-12-23-20(18)25/h2-4,9-10,12,14,26H,5-8,11H2,1H3,(H2,21,22,23) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097939
(7-Cyclopentyl-5-(3-methoxy-phenyl)-7H-pyrrolo[2,3-...)Show InChI InChI=1S/C18H20N4O/c1-23-14-8-4-5-12(9-14)15-10-22(13-6-2-3-7-13)18-16(15)17(19)20-11-21-18/h4-5,8-11,13H,2-3,6-7H2,1H3,(H2,19,20,21) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097958
(2-(4-(4-amino-5-(3-hydroxyphenyl)-7H-pyrrolo[2,3-d...)Show SMILES CN(C)C(=O)CN1CCC(CC1)n1cc(-c2cccc(O)c2)c2c(N)ncnc12 Show InChI InChI=1S/C21H26N6O2/c1-25(2)18(29)12-26-8-6-15(7-9-26)27-11-17(14-4-3-5-16(28)10-14)19-20(22)23-13-24-21(19)27/h3-5,10-11,13,15,28H,6-9,12H2,1-2H3,(H2,22,23,24) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414012
(CHEMBL473024)Show SMILES Nc1ncnc2n(cc(-c3ccc(O)cc3)c12)-c1ccc(OCCNCCO)cc1 Show InChI InChI=1S/C22H23N5O3/c23-21-20-19(15-1-5-17(29)6-2-15)13-27(22(20)26-14-25-21)16-3-7-18(8-4-16)30-12-10-24-9-11-28/h1-8,13-14,24,28-29H,9-12H2,(H2,23,25,26) | PDB
MMDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097942
(3-(4-Amino-7-cyclobutyl-7H-pyrrolo[2,3-d]pyrimidin...)Show InChI InChI=1S/C16H16N4O/c17-15-14-13(10-3-1-6-12(21)7-10)8-20(11-4-2-5-11)16(14)19-9-18-15/h1,3,6-9,11,21H,2,4-5H2,(H2,17,18,19) | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
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UniChem
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| Article
PubMed
| n/a | n/a | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413984
(CHEMBL470527)Show SMILES CCOC(=O)C[C@@H]1C[C@@H](CN1)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C20H23N5O3/c1-2-28-17(27)8-13-7-14(9-22-13)25-10-16(12-3-5-15(26)6-4-12)18-19(21)23-11-24-20(18)25/h3-6,10-11,13-14,22,26H,2,7-9H2,1H3,(H2,21,23,24)/t13-,14-/m0/s1 | PDB
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097974
(2-((2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2...)Show SMILES COc1cccc(c1)-c1cn(C2CCN(CCN(C)CCO)CC2)c2ncnc(N)c12 Show InChI InChI=1S/C23H32N6O2/c1-27(12-13-30)10-11-28-8-6-18(7-9-28)29-15-20(17-4-3-5-19(14-17)31-2)21-22(24)25-16-26-23(21)29/h3-5,14-16,18,30H,6-13H2,1-2H3,(H2,24,25,26) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414014
(CHEMBL475156)Show SMILES COCCNCCOc1cccc(c1)-n1cc(-c2cccc(O)c2)c2c(N)ncnc12 Show InChI InChI=1S/C23H25N5O3/c1-30-10-8-25-9-11-31-19-7-3-5-17(13-19)28-14-20(16-4-2-6-18(29)12-16)21-22(24)26-15-27-23(21)28/h2-7,12-15,25,29H,8-11H2,1H3,(H2,24,26,27) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088905
(2-(3-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)-c1cccc(CNCCO)c1 Show InChI InChI=1S/C21H21N5O/c22-20-19-18(16-6-2-1-3-7-16)13-26(21(19)25-14-24-20)17-8-4-5-15(11-17)12-23-9-10-27/h1-8,11,13-14,23,27H,9-10,12H2,(H2,22,24,25) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097951
(4-(4-Amino-7-cyclobutyl-7H-pyrrolo[2,3-d]pyrimidin...)Show InChI InChI=1S/C16H16N4O/c17-15-14-13(10-4-6-12(21)7-5-10)8-20(11-2-1-3-11)16(14)19-9-18-15/h4-9,11,21H,1-3H2,(H2,17,18,19) | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414004
(CHEMBL515751)Show SMILES COCCN(C)CCc1ccc(cc1)-n1cc(-c2cccc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C25H29N5O2/c1-29(13-14-31-2)12-11-18-7-9-20(10-8-18)30-16-22(19-5-4-6-21(15-19)32-3)23-24(26)27-17-28-25(23)30/h4-10,15-17H,11-14H2,1-3H3,(H2,26,27,28) | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413983
(CHEMBL475264)Show SMILES CCOC(=O)C[C@@H]1C[C@@H](CN1)n1cc(-c2ccccc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C20H23N5O2/c1-2-27-17(26)9-14-8-15(10-22-14)25-11-16(13-6-4-3-5-7-13)18-19(21)23-12-24-20(18)25/h3-7,11-12,14-15,22H,2,8-10H2,1H3,(H2,21,23,24)/t14-,15-/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088909
((4-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-...)Show InChI InChI=1S/C19H16N4O/c20-18-17-16(14-4-2-1-3-5-14)10-23(19(17)22-12-21-18)15-8-6-13(11-24)7-9-15/h1-10,12,24H,11H2,(H2,20,21,22) | PDB
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| CHEMBL
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UniChem
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| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414013
(CHEMBL474656)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(OCCNCCO)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C23H25N5O3/c1-30-19-4-2-3-16(13-19)20-14-28(23-21(20)22(24)26-15-27-23)17-5-7-18(8-6-17)31-12-10-25-9-11-29/h2-8,13-15,25,29H,9-12H2,1H3,(H2,24,26,27) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413999
(CGP77675 | CHEMBL475584)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCN3CCC(O)CC3)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C26H29N5O2/c1-33-22-4-2-3-19(15-22)23-16-31(26-24(23)25(27)28-17-29-26)20-7-5-18(6-8-20)9-12-30-13-10-21(32)11-14-30/h2-8,15-17,21,32H,9-14H2,1H3,(H2,27,28,29) | PDB
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414003
(CHEMBL470925)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCNCCO)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C23H25N5O2/c1-30-19-4-2-3-17(13-19)20-14-28(23-21(20)22(24)26-15-27-23)18-7-5-16(6-8-18)9-10-25-11-12-29/h2-8,13-15,25,29H,9-12H2,1H3,(H2,24,26,27) | PDB
MMDB
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UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088898
(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CC(=O)NCCO)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C23H23N5O3/c1-31-18-4-2-3-16(12-18)19-13-28(23-21(19)22(24)26-14-27-23)17-7-5-15(6-8-17)11-20(30)25-9-10-29/h2-8,12-14,29H,9-11H2,1H3,(H,25,30)(H2,24,26,27) | PDB
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| CHEMBL
KEGG
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414007
(CHEMBL474657)Show SMILES Nc1ncnc2n(cc(-c3cccc(F)c3)c12)-c1ccc(OCCNCCO)cc1 Show InChI InChI=1S/C22H22FN5O2/c23-16-3-1-2-15(12-16)19-13-28(22-20(19)21(24)26-14-27-22)17-4-6-18(7-5-17)30-11-9-25-8-10-29/h1-7,12-14,25,29H,8-11H2,(H2,24,26,27) | PDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414008
(CHEMBL473155)Show SMILES Nc1ncnc2n(cc(-c3cccc(Cl)c3)c12)-c1ccc(OCCNCCO)cc1 Show InChI InChI=1S/C22H22ClN5O2/c23-16-3-1-2-15(12-16)19-13-28(22-20(19)21(24)26-14-27-22)17-4-6-18(7-5-17)30-11-9-25-8-10-29/h1-7,12-14,25,29H,8-11H2,(H2,24,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097941
(4-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)Show InChI InChI=1S/C17H18N4O/c18-16-15-14(11-5-7-13(22)8-6-11)9-21(12-3-1-2-4-12)17(15)20-10-19-16/h5-10,12,22H,1-4H2,(H2,18,19,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097964
(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)Show SMILES COc1cccc(c1)-c1cn(C2CCN(CC(N)=O)CC2)c2ncnc(N)c12 Show InChI InChI=1S/C20H24N6O2/c1-28-15-4-2-3-13(9-15)16-10-26(20-18(16)19(22)23-12-24-20)14-5-7-25(8-6-14)11-17(21)27/h2-4,9-10,12,14H,5-8,11H2,1H3,(H2,21,27)(H2,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413993
(CHEMBL474825)Show SMILES CC(C)(C)OC(=O)N1C[C@@H](C[C@H]1CO)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H27N5O4/c1-22(2,3)31-21(30)27-9-14(8-15(27)11-28)26-10-17(13-4-6-16(29)7-5-13)18-19(23)24-12-25-20(18)26/h4-7,10,12,14-15,28-29H,8-9,11H2,1-3H3,(H2,23,24,25)/t14-,15+/m1/s1 | PDB
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UniChem
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PubMed
| n/a | n/a | 25.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097973
(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)Show SMILES COc1cccc(c1)-c1cn(C2CCN(CCO)CC2)c2ncnc(N)c12 Show InChI InChI=1S/C20H25N5O2/c1-27-16-4-2-3-14(11-16)17-12-25(20-18(17)19(21)22-13-23-20)15-5-7-24(8-6-15)9-10-26/h2-4,11-13,15,26H,5-10H2,1H3,(H2,21,22,23) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 25.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088899
(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CNCCO)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C22H23N5O2/c1-29-18-4-2-3-16(11-18)19-13-27(22-20(19)21(23)25-14-26-22)17-7-5-15(6-8-17)12-24-9-10-28/h2-8,11,13-14,24,28H,9-10,12H2,1H3,(H2,23,25,26) | PDB
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| CHEMBL
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UniChem
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| Article
PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413990
(CHEMBL470731)Show SMILES CCOC(=O)C[C@@H]1C[C@H](CN1C(=O)OC(C)(C)C)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C25H31N5O5/c1-5-34-20(32)11-16-10-17(12-30(16)24(33)35-25(2,3)4)29-13-19(15-6-8-18(31)9-7-15)21-22(26)27-14-28-23(21)29/h6-9,13-14,16-17,31H,5,10-12H2,1-4H3,(H2,26,27,28)/t16-,17+/m0/s1 | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088903
(2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCN(C)CCO)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C24H27N5O2/c1-28(12-13-30)11-10-17-6-8-19(9-7-17)29-15-21(18-4-3-5-20(14-18)31-2)22-23(25)26-16-27-24(22)29/h3-9,14-16,30H,10-13H2,1-2H3,(H2,25,26,27) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088912
(2-(4-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)-c1ccc(CNCCO)cc1 Show InChI InChI=1S/C21H21N5O/c22-20-19-18(16-4-2-1-3-5-16)13-26(21(19)25-14-24-20)17-8-6-15(7-9-17)12-23-10-11-27/h1-9,13-14,23,27H,10-12H2,(H2,22,24,25) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413978
(CHEMBL475355)Show SMILES CNC(=O)CNCCOc1ccc(cc1)-n1cc(-c2cccc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C24H26N6O3/c1-26-21(31)13-27-10-11-33-18-8-6-17(7-9-18)30-14-20(16-4-3-5-19(12-16)32-2)22-23(25)28-15-29-24(22)30/h3-9,12,14-15,27H,10-11,13H2,1-2H3,(H,26,31)(H2,25,28,29) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413980
(CHEMBL475414)Show SMILES OCCNCCOc1ccc(cc1)-n1cc(-c2cccc(O)c2)c2cncnc12 Show InChI InChI=1S/C22H22N4O3/c27-10-8-23-9-11-29-19-6-4-17(5-7-19)26-14-21(16-2-1-3-18(28)12-16)20-13-24-15-25-22(20)26/h1-7,12-15,23,27-28H,8-11H2 | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097945
(7-Cyclobutyl-5-(3-methoxy-phenyl)-7H-pyrrolo[2,3-d...)Show InChI InChI=1S/C17H18N4O/c1-22-13-7-2-4-11(8-13)14-9-21(12-5-3-6-12)17-15(14)16(18)19-10-20-17/h2,4,7-10,12H,3,5-6H2,1H3,(H2,18,19,20) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414002
(CHEMBL470746)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCN(C)C)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C23H25N5O/c1-27(2)12-11-16-7-9-18(10-8-16)28-14-20(17-5-4-6-19(13-17)29-3)21-22(24)25-15-26-23(21)28/h4-10,13-15H,11-12H2,1-3H3,(H2,24,25,26) | PDB
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097963
(7-(1-(2-((2-methoxyethyl)(methyl)amino)ethyl)piper...)Show SMILES COCCN(C)CCN1CCC(CC1)n1cc(-c2cccc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C24H34N6O2/c1-28(13-14-31-2)11-12-29-9-7-19(8-10-29)30-16-21(18-5-4-6-20(15-18)32-3)22-23(25)26-17-27-24(22)30/h4-6,15-17,19H,7-14H2,1-3H3,(H2,25,26,27) | PDB
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| Article
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| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413988
(CHEMBL471575)Show SMILES Nc1ncnc2n(cc(-c3ccc(O)cc3)c12)[C@@H]1CN[C@H](CO)C1 |r| Show InChI InChI=1S/C17H19N5O2/c18-16-15-14(10-1-3-13(24)4-2-10)7-22(17(15)21-9-20-16)12-5-11(8-23)19-6-12/h1-4,7,9,11-12,19,23-24H,5-6,8H2,(H2,18,20,21)/t11-,12-/m0/s1 | PDB
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| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414001
(CHEMBL511320)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CC(O)=O)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C21H18N4O3/c1-28-16-4-2-3-14(10-16)17-11-25(21-19(17)20(22)23-12-24-21)15-7-5-13(6-8-15)9-18(26)27/h2-8,10-12H,9H2,1H3,(H,26,27)(H2,22,23,24) | PDB
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| Article
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| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088908
(5-(3-Methoxy-phenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyr...)Show InChI InChI=1S/C19H16N4O/c1-24-15-9-5-6-13(10-15)16-11-23(14-7-3-2-4-8-14)19-17(16)18(20)21-12-22-19/h2-12H,1H3,(H2,20,21,22) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088902
((3-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-...)Show InChI InChI=1S/C19H16N4O/c20-18-17-16(14-6-2-1-3-7-14)10-23(19(17)22-12-21-18)15-8-4-5-13(9-15)11-24/h1-10,12,24H,11H2,(H2,20,21,22) | PDB
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UniChem
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| Article
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| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097961
(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)Show SMILES COc1cccc(c1)-c1cn(C2CCN(CC(=O)N(C)C)CC2)c2ncnc(N)c12 Show InChI InChI=1S/C22H28N6O2/c1-26(2)19(29)13-27-9-7-16(8-10-27)28-12-18(15-5-4-6-17(11-15)30-3)20-21(23)24-14-25-22(20)28/h4-6,11-12,14,16H,7-10,13H2,1-3H3,(H2,23,24,25) | PDB
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PC sid
UniChem
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PubMed
| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088904
((3-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]p...)Show SMILES COc1cccc(c1)-c1cn(-c2cccc(CO)c2)c2ncnc(N)c12 Show InChI InChI=1S/C20H18N4O2/c1-26-16-7-3-5-14(9-16)17-10-24(15-6-2-4-13(8-15)11-25)20-18(17)19(21)22-12-23-20/h2-10,12,25H,11H2,1H3,(H2,21,22,23) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097980
(CHEMBL169065 | methyl 2-(4-(4-amino-5-(3-methoxyph...)Show SMILES COC(=O)CN1CCC(CC1)n1cc(-c2cccc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C21H25N5O3/c1-28-16-5-3-4-14(10-16)17-11-26(21-19(17)20(22)23-13-24-21)15-6-8-25(9-7-15)12-18(27)29-2/h3-5,10-11,13,15H,6-9,12H2,1-2H3,(H2,22,23,24) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097954
(7-Cyclopentyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-...)Show InChI InChI=1S/C18H20N4O/c1-23-14-8-6-12(7-9-14)15-10-22(13-4-2-3-5-13)18-16(15)17(19)20-11-21-18/h6-11,13H,2-5H2,1H3,(H2,19,20,21) | PDB
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CHEMBL
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| Article
PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50132329
(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(CCO)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C21H20N4O2/c1-27-17-4-2-3-15(11-17)18-12-25(21-19(18)20(22)23-13-24-21)16-7-5-14(6-8-16)9-10-26/h2-8,11-13,26H,9-10H2,1H3,(H2,22,23,24) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088900
(5,7-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine ...)Show InChI InChI=1S/C18H14N4/c19-17-16-15(13-7-3-1-4-8-13)11-22(18(16)21-12-20-17)14-9-5-2-6-10-14/h1-12H,(H2,19,20,21) | PDB
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413995
(CHEMBL475008)Show SMILES Nc1ncnc2n(cc(-c3ccc(O)cc3)c12)[C@H]1CN[C@H](CO)C1 |r| Show InChI InChI=1S/C17H19N5O2/c18-16-15-14(10-1-3-13(24)4-2-10)7-22(17(15)21-9-20-16)12-5-11(8-23)19-6-12/h1-4,7,9,11-12,19,23-24H,5-6,8H2,(H2,18,20,21)/t11-,12+/m0/s1 | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414021
(CHEMBL513563)Show SMILES CCOC(=O)C[C@@H]1C[C@H](CN1)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C20H23N5O3/c1-2-28-17(27)8-13-7-14(9-22-13)25-10-16(12-3-5-15(26)6-4-12)18-19(21)23-11-24-20(18)25/h3-6,10-11,13-14,22,26H,2,7-9H2,1H3,(H2,21,23,24)/t13-,14+/m0/s1 | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097936
(7-Cyclobutyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4...)Show InChI InChI=1S/C16H16N4/c17-15-14-13(11-5-2-1-3-6-11)9-20(12-7-4-8-12)16(14)19-10-18-15/h1-3,5-6,9-10,12H,4,7-8H2,(H2,17,18,19) | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097955
(7-Cyclopentyl-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)Show InChI InChI=1S/C17H18N4/c18-16-15-14(12-6-2-1-3-7-12)10-21(13-8-4-5-9-13)17(15)20-11-19-16/h1-3,6-7,10-11,13H,4-5,8-9H2,(H2,18,19,20) | PDB
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413987
(CHEMBL471574)Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)[C@@H]1CN[C@H](CO)C1 |r| Show InChI InChI=1S/C17H19N5O/c18-16-15-14(11-4-2-1-3-5-11)8-22(17(15)21-10-20-16)13-6-12(9-23)19-7-13/h1-5,8,10,12-13,19,23H,6-7,9H2,(H2,18,20,21)/t12-,13-/m0/s1 | PDB
MMDB
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UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413979
(CHEMBL475413)Show SMILES COc1cccc(c1)-c1cn(-c2ccc(OCCn3ccnc3)cc2)c2ncnc(N)c12 Show InChI InChI=1S/C24H22N6O2/c1-31-20-4-2-3-17(13-20)21-14-30(24-22(21)23(25)27-15-28-24)18-5-7-19(8-6-18)32-12-11-29-10-9-26-16-29/h2-10,13-16H,11-12H2,1H3,(H2,25,27,28) | PDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413992
(CHEMBL514652)Show SMILES CC(C)(C)OC(=O)N1C[C@@H](C[C@H]1CO)n1cc(-c2ccccc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H27N5O3/c1-22(2,3)30-21(29)27-10-15(9-16(27)12-28)26-11-17(14-7-5-4-6-8-14)18-19(23)24-13-25-20(18)26/h4-8,11,13,15-16,28H,9-10,12H2,1-3H3,(H2,23,24,25)/t15-,16+/m1/s1 | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414009
(CHEMBL475354)Show SMILES COCCNCCOc1cccc(c1)-n1cc(-c2cccc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C24H27N5O3/c1-30-11-9-26-10-12-32-20-8-4-6-18(14-20)29-15-21(17-5-3-7-19(13-17)31-2)22-23(25)27-16-28-24(22)29/h3-8,13-16,26H,9-12H2,1-2H3,(H2,25,27,28) | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088913
(5-(4-Methoxy-phenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyr...)Show InChI InChI=1S/C19H16N4O/c1-24-15-9-7-13(8-10-15)16-11-23(14-5-3-2-4-6-14)19-17(16)18(20)21-12-22-19/h2-12H,1H3,(H2,20,21,22) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50097950
(7-Cyclobutyl-5-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d...)Show InChI InChI=1S/C17H18N4O/c1-22-13-7-5-11(6-8-13)14-9-21(12-3-2-4-12)17-15(14)16(18)19-10-20-17/h5-10,12H,2-4H2,1H3,(H2,18,19,20) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088910
(5-(3-Chloro-phenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyri...)Show InChI InChI=1S/C18H13ClN4/c19-13-6-4-5-12(9-13)15-10-23(14-7-2-1-3-8-14)18-16(15)17(20)21-11-22-18/h1-11H,(H2,20,21,22) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413996
(CHEMBL474237)Show InChI InChI=1S/C16H18N4O2/c17-15-14-13(12-4-2-1-3-5-12)7-20(6-11(8-21)9-22)16(14)19-10-18-15/h1-5,7,10-11,21-22H,6,8-9H2,(H2,17,18,19) | PDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413972
(CHEMBL509767)Show InChI InChI=1S/C15H14N4/c16-14-13-12(10-4-2-1-3-5-10)8-19(11-6-7-11)15(13)18-9-17-14/h1-5,8-9,11H,6-7H2,(H2,16,17,18) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413982
(CHEMBL475263)Show SMILES CCOC(=O)C[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C25H31N5O5/c1-5-34-20(32)11-16-10-17(12-30(16)24(33)35-25(2,3)4)29-13-19(15-6-8-18(31)9-7-15)21-22(26)27-14-28-23(21)29/h6-9,13-14,16-17,31H,5,10-12H2,1-4H3,(H2,26,27,28)/t16-,17-/m0/s1 | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413994
(CHEMBL474834)Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)[C@H]1CN[C@H](CO)C1 |r| Show InChI InChI=1S/C17H19N5O/c18-16-15-14(11-4-2-1-3-5-11)8-22(17(15)21-10-20-16)13-6-12(9-23)19-7-13/h1-5,8,10,12-13,19,23H,6-7,9H2,(H2,18,20,21)/t12-,13+/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413986
(CHEMBL513043)Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1CO)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H27N5O4/c1-22(2,3)31-21(30)27-9-14(8-15(27)11-28)26-10-17(13-4-6-16(29)7-5-13)18-19(23)24-12-25-20(18)26/h4-7,10,12,14-15,28-29H,8-9,11H2,1-3H3,(H2,23,24,25)/t14-,15-/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413998
(CHEMBL512352)Show InChI InChI=1S/C17H20N4O3/c1-24-13-4-2-3-12(5-13)14-7-21(6-11(8-22)9-23)17-15(14)16(18)19-10-20-17/h2-5,7,10-11,22-23H,6,8-9H2,1H3,(H2,18,19,20) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088907
((2-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-7-...)Show InChI InChI=1S/C19H16N4O/c20-18-17-15(13-6-2-1-3-7-13)10-23(19(17)22-12-21-18)16-9-5-4-8-14(16)11-24/h1-10,12,24H,11H2,(H2,20,21,22) | PDB
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| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413989
(CHEMBL511157)Show SMILES CCOC(=O)C[C@@H]1C[C@H](CN1C(=O)OC(C)(C)C)n1cc(-c2ccccc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C25H31N5O4/c1-5-33-20(31)12-17-11-18(13-30(17)24(32)34-25(2,3)4)29-14-19(16-9-7-6-8-10-16)21-22(26)27-15-28-23(21)29/h6-10,14-15,17-18H,5,11-13H2,1-4H3,(H2,26,27,28)/t17-,18+/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413997
(CHEMBL471914)Show InChI InChI=1S/C16H18N4O3/c17-15-14-13(11-1-3-12(23)4-2-11)6-20(5-10(7-21)8-22)16(14)19-9-18-15/h1-4,6,9-10,21-23H,5,7-8H2,(H2,17,18,19) | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM3003
(1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |...)Show InChI InChI=1S/C17H13N5/c18-16-14-15(12-7-3-1-4-8-12)21-22(17(14)20-11-19-16)13-9-5-2-6-10-13/h1-11H,(H2,18,19,20) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50403911
(CHEMBL471945)Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)[C@@H](CO)c1ccccc1 |r| Show InChI InChI=1S/C20H18N4O/c21-19-18-16(14-7-3-1-4-8-14)11-24(20(18)23-13-22-19)17(12-25)15-9-5-2-6-10-15/h1-11,13,17,25H,12H2,(H2,21,22,23)/t17-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413991
(CHEMBL470732)Show SMILES CCOC(=O)C[C@@H]1C[C@H](CN1)n1cc(-c2ccccc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C20H23N5O2/c1-2-27-17(26)9-14-8-15(10-22-14)25-11-16(13-6-4-3-5-7-13)18-19(21)23-12-24-20(18)25/h3-7,11-12,14-15,22H,2,8-10H2,1H3,(H2,21,23,24)/t14-,15+/m0/s1 | PDB
MMDB
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UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413985
(CHEMBL470708)Show SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1CO)n1cc(-c2ccccc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H27N5O3/c1-22(2,3)30-21(29)27-10-15(9-16(27)12-28)26-11-17(14-7-5-4-6-8-14)18-19(23)24-13-25-20(18)26/h4-8,11,13,15-16,28H,9-10,12H2,1-3H3,(H2,23,24,25)/t15-,16-/m0/s1 | PDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414015
(CHEMBL475189)Show InChI InChI=1S/C17H20N4O2/c18-16-15-14(13-4-2-1-3-5-13)8-21(17(15)20-11-19-16)7-6-12(9-22)10-23/h1-5,8,11-12,22-23H,6-7,9-10H2,(H2,18,19,20) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50403912
(CHEMBL511124)Show SMILES Nc1ncnc2n(cc(-c3ccccc3)c12)[C@H](CO)c1ccccc1 |r| Show InChI InChI=1S/C20H18N4O/c21-19-18-16(14-7-3-1-4-8-14)11-24(20(18)23-13-22-19)17(12-25)15-9-5-2-6-10-15/h1-11,13,17,25H,12H2,(H2,21,22,23)/t17-/m1/s1 | PDB
MMDB
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088911
(2-(2-(4-amino-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)Show InChI InChI=1S/C21H21N5O/c22-20-19-17(15-6-2-1-3-7-15)13-26(21(19)25-14-24-20)18-9-5-4-8-16(18)12-23-10-11-27/h1-9,13-14,23,27H,10-12H2,(H2,22,24,25) | PDB
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PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50413981
(CHEMBL516072)Show SMILES CCOC(=O)C[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)n1cc(-c2ccccc2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C25H31N5O4/c1-5-33-20(31)12-17-11-18(13-30(17)24(32)34-25(2,3)4)29-14-19(16-9-7-6-8-10-16)21-22(26)27-15-28-23(21)29/h6-10,14-15,17-18H,5,11-13H2,1-4H3,(H2,26,27,28)/t17-,18-/m0/s1 | PDB
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| CHEMBL
PC cid
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UniChem
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PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50414000
(CHEMBL511495)Show InChI InChI=1S/C19H16N4O/c1-24-16-10-6-5-9-14(16)15-11-23(13-7-3-2-4-8-13)19-17(15)18(20)21-12-22-19/h2-12H,1H3,(H2,20,21,22) | PDB
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UniChem
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PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088916
(4-Chloro-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidine ...)Show InChI InChI=1S/C18H12ClN3/c19-17-16-15(13-7-3-1-4-8-13)11-22(18(16)21-12-20-17)14-9-5-2-6-10-14/h1-12H | PDB
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UniChem
| Article
PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088906
((5,7-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-met...)Show InChI InChI=1S/C19H16N4/c1-20-18-17-16(14-8-4-2-5-9-14)12-23(19(17)22-13-21-18)15-10-6-3-7-11-15/h2-13H,1H3,(H,20,21,22) | PDB
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PC cid
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| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088914
(4-(4-Amino-7-phenyl-7H-pyrrolo[2,3-d]pyrimidin-5-y...)Show SMILES CCOC(=O)c1ccc(cc1)-c1cn(-c2ccccc2)c2ncnc(N)c12 Show InChI InChI=1S/C21H18N4O2/c1-2-27-21(26)15-10-8-14(9-11-15)17-12-25(16-6-4-3-5-7-16)20-18(17)19(22)23-13-24-20/h3-13H,2H2,1H3,(H2,22,23,24) | PDB
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PC sid
UniChem
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PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50088915
(5,7-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol | 5,7...)Show InChI InChI=1S/C18H13N3O/c22-18-16-15(13-7-3-1-4-8-13)11-21(17(16)19-12-20-18)14-9-5-2-6-10-14/h1-12H,(H,19,20,22) | PDB
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UniProtKB/SwissProt
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PC cid
PC sid
UniChem
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PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Inhibition of c-Src |
Eur J Med Chem 44: 990-1000 (2009)
Article DOI: 10.1016/j.ejmech.2008.07.002
BindingDB Entry DOI: 10.7270/Q2ZC8434 |
More data for this
Ligand-Target Pair | |
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