Affinity Data by PubMed id=18774720

PubMed code 18774720

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247055 (1-(3-(3-phenylpropoxy)propyl)piperidine \| CHEMBL46...) Show SMILES C(COCCCc1ccccc1)CN1CCCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from human histamine H3 receptor expressed in rat C6 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247148 (1-[3-(4-tert-Butylphenoxy)propyl]-4-piperidino-pip...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247120 (1-[2-(3-Methoxyphenoxy)ethyl]-4-piperidino-piperid...) Show SMILES COc1cccc(OCCN2CCC(CC2)N2CCCCC2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247122 (1-[2-(3-Trifluoromethylphenoxy)ethyl]-4-piperidino...) Show SMILES FC(F)(F)c1cccc(OCCN2CCC(CC2)N2CCCCC2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	164	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247125 (1-[3-(4-Chlorophenoxy)propyl]-4-piperidino-piperid...) Show SMILES Clc1ccc(OCCCN2CCC(CC2)N2CCCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	165	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247124 (1-[2-(4-Chlorophenoxy)ethyl]-4-piperidino-piperidi...) Show SMILES Clc1ccc(OCCN2CCC(CC2)N2CCCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247093 (1-[2-(3-Chlorophenoxy)ethyl]-4-piperidino-piperidi...) Show SMILES Clc1cccc(OCCN2CCC(CC2)N2CCCCC2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	235	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247089 (4-Propyl-1-[3-(phenylpropoxy)propyl]piperidine \| C...) Show SMILES CCCC1CCN(CCCOCCCc2ccccc2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	249	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247090 (4-Butyl-1-[3-(phenylpropoxy)propyl]piperidine \| CH...) Show SMILES CCCCC1CCN(CCCOCCCc2ccccc2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	274	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247123 (1-[2-(4-Methylphenoxy)ethyl]-4-piperidino-piperidi...) Show SMILES Cc1ccc(OCCN2CCC(CC2)N2CCCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247091 (4-Benzyl-1-[3-phenylpropoxy)propyl]piperidine \| CH...) Show SMILES C(COCCCc1ccccc1)CN1CCC(Cc2ccccc2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	326	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247092 (2-[3-(3-phenylpropoxy)propyl]decahydroisoquinoline...) Show SMILES C(COCCCc1ccccc1)CN1CCC2CCCCC2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	393	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247088 (2-[3-(3-Phenylpropoxy)propyl]-1,2,3,4-tetrahydro-i...) Show SMILES C(COCCCc1ccccc1)CN1CCc2ccccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247121 (1-[3-(3-Methoxyphenoxy)propyl]-4-piperidino-piperi...) Show SMILES COc1cccc(OCCCN2CCC(CC2)N2CCCCC2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem 16: 8729-36 (2008) Article DOI: 10.1016/j.bmc.2008.07.071 BindingDB Entry DOI: 10.7270/Q2NC612W
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%