Affinity Data by PubMed id=18789705

PubMed code 18789705

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Papain (Carica papaya)	BDBM50265074 (CHEMBL525792 \| Cbz-Phe-[Gly-cis epoxy-Gly]-Ala-Ala...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Binding affinity to Carica papaya papain treated up to 2 hrs at 25 degC by Dixon plot				Bioorg Med Chem 16: 9032-9 (2008) Article DOI: 10.1016/j.bmc.2008.08.031 BindingDB Entry DOI: 10.7270/Q2XP74SH
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50265073 (CHEMBL500638 \| Cbz-Phe-[Gly-trans epoxy-Gly]-Ala-A...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Binding affinity to Carica papaya papain treated up to 2 hrs at 25 degC by Dixon plot				Bioorg Med Chem 16: 9032-9 (2008) Article DOI: 10.1016/j.bmc.2008.08.031 BindingDB Entry DOI: 10.7270/Q2XP74SH
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50265074 (CHEMBL525792 \| Cbz-Phe-[Gly-cis epoxy-Gly]-Ala-Ala...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	9.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Binding affinity to cathepsin B (unknown origin) treated up to 2 hrs at 37degC by Dixon plot				Bioorg Med Chem 16: 9032-9 (2008) Article DOI: 10.1016/j.bmc.2008.08.031 BindingDB Entry DOI: 10.7270/Q2XP74SH
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50265073 (CHEMBL500638 \| Cbz-Phe-[Gly-trans epoxy-Gly]-Ala-A...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.44E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Binding affinity to cathepsin B (unknown origin) treated up to 2 hrs at 37degC by Dixon plot				Bioorg Med Chem 16: 9032-9 (2008) Article DOI: 10.1016/j.bmc.2008.08.031 BindingDB Entry DOI: 10.7270/Q2XP74SH
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50265075 (CHEMBL498580 \| Cbz-Phe-Gly-epoxide) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Binding affinity to Carica papaya papain treated up to 2 hrs at 25 degC by Dixon plot				Bioorg Med Chem 16: 9032-9 (2008) Article DOI: 10.1016/j.bmc.2008.08.031 BindingDB Entry DOI: 10.7270/Q2XP74SH
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50265075 (CHEMBL498580 \| Cbz-Phe-Gly-epoxide) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Binding affinity to cathepsin B (unknown origin) treated up to 2 hrs at 37degC by Dixon plot				Bioorg Med Chem 16: 9032-9 (2008) Article DOI: 10.1016/j.bmc.2008.08.031 BindingDB Entry DOI: 10.7270/Q2XP74SH
Bar Ilan University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%