Affinity Data by PubMed id=18800848

PubMed code 18800848

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50253285 (4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from human cloned adrenergic alpha2a receptor				J Nat Prod 71: 1783-6 (2008) Article DOI: 10.1021/np800339e BindingDB Entry DOI: 10.7270/Q2QZ29SK
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50253285 (4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	275	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of cloned adrenergic alpha1D receptor (unknown origin)				J Nat Prod 71: 1783-6 (2008) Article DOI: 10.1021/np800339e BindingDB Entry DOI: 10.7270/Q2QZ29SK
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50253285 (4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [125I]-APT from histamine H2 receptor in brain of guinea pig				J Nat Prod 71: 1783-6 (2008) Article DOI: 10.1021/np800339e BindingDB Entry DOI: 10.7270/Q2QZ29SK
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50253285 (4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]SMT from histamine H3 receptor in forebrain of rat				J Nat Prod 71: 1783-6 (2008) Article DOI: 10.1021/np800339e BindingDB Entry DOI: 10.7270/Q2QZ29SK
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50253285 (4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from human cloned adrenergic alpha2a receptor				J Nat Prod 71: 1783-6 (2008) Article DOI: 10.1021/np800339e BindingDB Entry DOI: 10.7270/Q2QZ29SK
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50253285 (4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of cloned adrenergic alpha1D receptor (unknown origin)				J Nat Prod 71: 1783-6 (2008) Article DOI: 10.1021/np800339e BindingDB Entry DOI: 10.7270/Q2QZ29SK
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50253285 (4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [125I]-APT from histamine H2 receptor in brain of guinea pig				J Nat Prod 71: 1783-6 (2008) Article DOI: 10.1021/np800339e BindingDB Entry DOI: 10.7270/Q2QZ29SK
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50253285 (4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]SMT from histamine H3 receptor in forebrain of rat				J Nat Prod 71: 1783-6 (2008) Article DOI: 10.1021/np800339e BindingDB Entry DOI: 10.7270/Q2QZ29SK
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%