Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM50232538 (5-((1-(2-fluorobenzyl)piperidin-4-yl)methoxy)quina...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 7.62 | n/a | 4 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM36533 (D157555) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.38 | n/a | 108 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM36531 (D158963) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23.4 | n/a | 223 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM36530 (D157493) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 43.9 | n/a | 67 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM36532 (D158885) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 101 | n/a | 795 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM36529 (D156676) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 339 | n/a | 2.54E+3 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM36535 (D157554) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 921 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM36536 (D153215) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 243 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
m7GpppX diphosphatase (Homo sapiens (Human)) | BDBM36534 (D156095) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 104 | n/a | n/a | n/a | n/a |
deCODE chemistry, Inc. | Assay Description In vitro biochemical assay using scavenger decapping enzyme (DcpS) as a target and cell based assay using SMN2 b-lactamase NSC-34 cell reporter gene. | ACS Chem Biol 3: 711-22 (2008) Article DOI: 10.1021/cb800120t BindingDB Entry DOI: 10.7270/Q2Z036HN | |||||||||||
More data for this Ligand-Target Pair |