Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM50274325 ((R)-4-(4-((2-(4-Chlorophenyl)-5,5-dimethylcyclohex...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of fluorescein labeled BAD peptide from Bcl-XL (unknown origin) by fluorescence polarization assay | J Med Chem 51: 6902-15 (2008) Article DOI: 10.1021/jm800669s BindingDB Entry DOI: 10.7270/Q2057FR7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM50274326 ((R)-4-(4-((4-(4-Chlorophenyl)-5,6-dihydro-2H-pyran...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of fluorescein labeled Bax peptide from Bcl2 (unknown origin) by fluorescence polarization assay | J Med Chem 51: 6902-15 (2008) Article DOI: 10.1021/jm800669s BindingDB Entry DOI: 10.7270/Q2057FR7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM50274315 ((R)-4-(4-((4'-Chlorobiphenyl-2-yl)methyl)piperazin...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of fluorescein labeled BAD peptide from Bcl-XL (unknown origin) by fluorescence polarization assay | J Med Chem 51: 6902-15 (2008) Article DOI: 10.1021/jm800669s BindingDB Entry DOI: 10.7270/Q2057FR7 | |||||||||||
More data for this Ligand-Target Pair |