Affinity Data by PubMed id=18855373

PubMed code 18855373

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM22858 (1,2-Dione-Based Compound, 15 \| 2-nitro-9,10-dihydr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	6.81E+3	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25463 (2-(1,2,4-triazatriphenylen-3-ylsulfanyl)acetic aci...) Show SMILES OC(=O)CSc1nnc2c3ccccc3c3ccccc3c2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.69E+4	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25466 (N-(3-nitro-9-oxo-9H-fluoren-2-yl)acetamide \| NSC60...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.18E+4	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25469 (2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]-1-o...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.95E+4	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25468 (3,7-difluoro-2-nitro-9H-fluoren-9-one \| NSC57476) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.46E+4	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25467 (2,4-dinitro-9H-fluoren-9-one \| NSC55545) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	4.81E+4	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25460 (2-[(4-oxo-4H-triphenylene-11-)sulfinyl]acetic acid...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	1.80E+5	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25462 (2,3-dinitro-9H-fluoren-9-one \| NSC133896) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.71E+4	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25464 (6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]-9H-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	1.52E+4	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair
Adenosine 5'-phosphosulfate reductase (Mycobacterium tuberculosis)	BDBM25465 ((1R,2R,5S,6S,10S,13S,15R)-5-acetyl-13-hydroxy-6,10...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.27E+5	n/a	n/a	n/a	7.5	30
The Scripps Research Institute					Assay Description Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...				J Med Chem 51: 6627-30 (2008) Article DOI: 10.1021/jm800571m BindingDB Entry DOI: 10.7270/Q2PK0DFG
The Scripps Research Institute					More data for this Ligand-Target Pair

* indicates data uncertainty>20%