Affinity Data by PubMed id=18996017

PubMed code 18996017

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM50246505 (2-(N'-4-chloro-benzylidenehydrazino)-4-trifluorome...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50246506 (2-(N'-4-methoxy-benzylidenehydrazino)-4-trifluorom...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50246508 (2-(N'-2-Methyl-benzylidenehydrazino)-6-methyl-4-tr...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50246463 (2-(N'-2-Methyl-benzylidenehydrazino)-4-trifluorome...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50246504 (2-(N'-4-Methyl-benzylidenehydrazino)-4-trifluorome...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50246507 (2-(N'-4-Nitro-benzylidenehydrazino)-4-trifluoromet...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50245873 (2-(N'-4-chloro-benzylidenehydrazino)-6-methyl-4-tr...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50246509 (2-(N'-2-Methoxy-benzylidenehydrazino)-6-methyl-4-t...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50246462 (2-(N'-Benzylidenehydrazino)-4-trifluoromethylpyrim...) Show SMILES FC(F)(F)c1ccnc(N=NCc2ccccc2)n1 \|w:9.8\| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Maria Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi C-terminal truncated cruzain expressed in DH5alpha Escherichia coli by well-microplate spectrophotometry				Bioorg Med Chem 16: 10236-43 (2008) Article DOI: 10.1016/j.bmc.2008.10.052 BindingDB Entry DOI: 10.7270/Q2PC327Q
Universidade Federal de Santa Maria Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%