Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Aldo-keto reductase family 1 member B1 [K65Q] (Bos taurus (Cattle)) | BDBM16314 (2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description In vitro inhibition of aldose reductase in partially purified bovine lens preparation at a concentration of 10e -8M. | J Med Chem 34: 1492-503 (1991) BindingDB Entry DOI: 10.7270/Q2WM1CCR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |