Affinity Data by PubMed id=19042133

PubMed code 19042133

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50265823 (CHEMBL516634 \| candelalide B) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of voltage-gated Kv1.3 potassium channel (unknown origin) expressed in CHO cells by 86Rb efflux experiment				Bioorg Med Chem 17: 2304-9 (2009) Article DOI: 10.1016/j.bmc.2008.11.001 BindingDB Entry DOI: 10.7270/Q2R21172
Institute of Molecular Physiology Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50265824 (CHEMBL460814 \| candelalide C) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of voltage-gated Kv1.3 potassium channel (unknown origin) expressed in CHO cells by 86Rb efflux experiment				Bioorg Med Chem 17: 2304-9 (2009) Article DOI: 10.1016/j.bmc.2008.11.001 BindingDB Entry DOI: 10.7270/Q2R21172
Institute of Molecular Physiology Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50266317 (CHEMBL515037 \| candelalide A) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of voltage-gated Kv1.3 potassium channel (unknown origin) expressed in CHO cells by 86Rb efflux experiment				Bioorg Med Chem 17: 2304-9 (2009) Article DOI: 10.1016/j.bmc.2008.11.001 BindingDB Entry DOI: 10.7270/Q2R21172
Institute of Molecular Physiology Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50265825 (CHEMBL516932 \| Nalanthalide) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular Physiology Curated by ChEMBL					Assay Description Antagonist activity at voltage-gated Kv1.3 potassium channel (unknown origin)				Bioorg Med Chem 17: 2304-9 (2009) Article DOI: 10.1016/j.bmc.2008.11.001 BindingDB Entry DOI: 10.7270/Q2R21172
Institute of Molecular Physiology Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%