Affinity Data by PubMed id=1906108

PubMed code 1906108

Found 27 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM16312 ((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...) Show SMILES Fc1ccc2OCC[C@]3(NC(=O)NC3=O)c2c1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description The compound was tested for the inhibition of Aldose reductase in rat lens assay.				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM16312 ((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...) Show SMILES Fc1ccc2OCC[C@]3(NC(=O)NC3=O)c2c1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50010002 (CHEMBL302057 \| [(4-Benzoylamino-benzoyl)-phenyl-am...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009985 (CHEMBL69716 \| [(4-Nitro-benzoyl)-phenyl-amino]-ace...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009990 (CHEMBL305251 \| [(4-Benzoylamino-benzoyl)-methyl-am...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009983 (CHEMBL308898 \| [(4-Methoxy-benzoyl)-phenyl-amino]-...) Show SMILES COc1ccc(cc1)C(=O)N(CC(O)=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009992 (CHEMBL69549 \| [(4-Methyl-benzoyl)-phenyl-amino]-ac...) Show SMILES Cc1ccc(cc1)C(=O)N(CC(O)=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009997 ((Benzoyl-phenyl-amino)-acetic acid \| CHEMBL273228) Show SMILES OC(=O)CN(C(=O)c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009978 (CHEMBL66711 \| [(4-Methoxy-benzoyl)-methyl-amino]-a...) Show SMILES COc1ccc(cc1)C(=O)N(C)CC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009984 (CHEMBL66216 \| [(4-Fluoro-benzoyl)-phenyl-amino]-ac...) Show SMILES OC(=O)CN(C(=O)c1ccc(F)cc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009980 (CHEMBL266688 \| [(Naphthalene-1-carbonyl)-phenyl-am...) Show SMILES OC(=O)CN(C(=O)c1cccc2ccccc12)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009988 (CHEMBL308007 \| [(4-Fluoro-benzoyl)-methyl-amino]-a...) Show SMILES CN(CC(O)=O)C(=O)c1ccc(F)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009996 ((4-Benzoylamino-benzoylamino)-acetic acid \| CHEMBL...) Show SMILES OC(=O)CNC(=O)c1ccc(NC(=O)c2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009986 (CHEMBL67361 \| [(4-Amino-benzoyl)-methyl-amino]-ace...) Show SMILES CN(CC(O)=O)C(=O)c1ccc(N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009979 (CHEMBL67330 \| [(4-Amino-benzoyl)-phenyl-amino]-ace...) Show SMILES Nc1ccc(cc1)C(=O)N(CC(O)=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009987 (CHEMBL67014 \| [Methyl-(4-methyl-benzoyl)-amino]-ac...) Show SMILES CN(CC(O)=O)C(=O)c1ccc(C)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009991 (CHEMBL67731 \| [Methyl-(naphthalene-2-carbonyl)-ami...) Show SMILES CN(CC(O)=O)C(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009981 (CHEMBL305492 \| [(Naphthalene-2-carbonyl)-phenyl-am...) Show SMILES OC(=O)CN(C(=O)c1ccc2ccccc2c1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009994 ((4-Phenylacetylamino-benzoylamino)-acetic acid \| C...) Show SMILES OC(=O)CNC(=O)c1ccc(NC(=O)Cc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009998 ((Benzoyl-methyl-amino)-acetic acid \| CHEMBL66391) Show SMILES CN(CC(O)=O)C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50010001 (CHEMBL68391 \| [Methyl-(4-nitro-benzoyl)-amino]-ace...) Show SMILES CN(CC(O)=O)C(=O)c1ccc(cc1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009989 (CHEMBL66895 \| [Methyl-(naphthalene-1-carbonyl)-ami...) Show SMILES CN(CC(O)=O)C(=O)c1cccc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009993 (CHEMBL67410 \| [4-(3-Phenyl-propionylamino)-benzoyl...) Show SMILES OC(=O)CNC(=O)c1ccc(NC(=O)CCc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50010000 ((3-Benzoylamino-benzoylamino)-acetic acid \| CHEMBL...) Show SMILES OC(=O)CNC(=O)c1cccc(NC(=O)c2ccccc2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009982 (CHEMBL8798 \| [(Naphthalene-2-carbonyl)-amino]-acet...) Show SMILES OC(=O)CNC(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009995 (2-(1-naphthamido)acetate \| CHEMBL306898 \| [(Naphth...) Show SMILES OC(=O)CNC(=O)c1cccc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50009999 (CHEMBL461 \| N-benzoylglycine) Show SMILES OC(=O)CNC(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Auburn University Curated by ChEMBL					Assay Description Inhibitory activity against aldose reductase in rat lens				J Med Chem 34: 2120-6 (1991) BindingDB Entry DOI: 10.7270/Q2N29VX2
Auburn University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%