Affinity Data by PubMed id=19110422

PubMed code 19110422

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50256010 (3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4811 ((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50256010 (3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50256010 (3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of human FGFR1 expressed in insect cells by HTRF method				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50217602 ((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of human FGFR1 expressed in insect cells by HTRF method				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4811 ((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50217602 ((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50217602 ((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM4811 ((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of human FGFR1 expressed in insect cells by HTRF method				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50256010 (3-{2,4-dimethyl-5-[2-oxo-5-(N'-phenylhydrazinocarb...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4811 ((Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50217602 ((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Mahidol University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin)				Bioorg Med Chem Lett 19: 745-50 (2009) Article DOI: 10.1016/j.bmcl.2008.12.023 BindingDB Entry DOI: 10.7270/Q2028RDT
Mahidol University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%