Found 69 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293389
(CHEMBL553237 | {(3S)-5-[2-({4-[Amino(imino)methyl]...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(CC(O)=O)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C28H29N5O6S2/c29-27(30)21-9-6-18(7-10-21)14-31-25(34)15-33-23-12-20(13-26(35)36)8-11-24(23)40-16-22(28(33)37)32-41(38,39)17-19-4-2-1-3-5-19/h1-12,22,32H,13-17H2,(H3,29,30)(H,31,34)(H,35,36)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293383
(2-[(3S)-3-[Benzylsulfonylamino]-7-(3-nitrophenyl)-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)-c2cccc(c2)[N+]([O-])=O)cc1 |r| Show InChI InChI=1S/C32H30N6O6S2/c33-31(34)23-11-9-21(10-12-23)17-35-30(39)18-37-28-16-25(24-7-4-8-26(15-24)38(41)42)13-14-29(28)45-19-27(32(37)40)36-46(43,44)20-22-5-2-1-3-6-22/h1-16,27,36H,17-20H2,(H3,33,34)(H,35,39)/t27-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293387
(2-[(3S)-8-Aminomethyl-3-[benzylsulfonylamino]-4-ox...)Show SMILES NCc1ccc2N(CC(=O)NCc3ccc(cc3)C(N)=N)C(=O)[C@@H](CSc2c1)NS(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C27H30N6O4S2/c28-13-20-8-11-23-24(12-20)38-16-22(32-39(36,37)17-19-4-2-1-3-5-19)27(35)33(23)15-25(34)31-14-18-6-9-21(10-7-18)26(29)30/h1-12,22,32H,13-17,28H2,(H3,29,30)(H,31,34)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293384
(2-Amino-3-{(3S)-5-[2-({4-[amino(imino)methyl]benzy...)Show SMILES NC(Cc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1)C(O)=O |r| Show InChI InChI=1S/C29H32N6O6S2/c30-22(29(38)39)12-20-8-11-25-24(13-20)35(15-26(36)33-14-18-6-9-21(10-7-18)27(31)32)28(37)23(16-42-25)34-43(40,41)17-19-4-2-1-3-5-19/h1-11,13,22-23,34H,12,14-17,30H2,(H3,31,32)(H,33,36)(H,38,39)/t22?,23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293385
(2-[(3S)-7-[2-Aminoethyl]-3-[benzylsulfonylamino]-4...)Show SMILES NCCc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1 |r| Show InChI InChI=1S/C28H32N6O4S2/c29-13-12-19-8-11-25-24(14-19)34(16-26(35)32-15-20-6-9-22(10-7-20)27(30)31)28(36)23(17-39-25)33-40(37,38)18-21-4-2-1-3-5-21/h1-11,14,23,33H,12-13,15-18,29H2,(H3,30,31)(H,32,35)/t23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293384
(2-Amino-3-{(3S)-5-[2-({4-[amino(imino)methyl]benzy...)Show SMILES NC(Cc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1)C(O)=O |r| Show InChI InChI=1S/C29H32N6O6S2/c30-22(29(38)39)12-20-8-11-25-24(13-20)35(15-26(36)33-14-18-6-9-21(10-7-18)27(31)32)28(37)23(16-42-25)34-43(40,41)17-19-4-2-1-3-5-19/h1-11,13,22-23,34H,12,14-17,30H2,(H3,31,32)(H,33,36)(H,38,39)/t22?,23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293391
(2-[(3S)-7-Amino-3-[benzylsulfonylamino]-4-oxo-3,4-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(N)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H28N6O4S2/c27-20-10-11-23-22(12-20)32(14-24(33)30-13-17-6-8-19(9-7-17)25(28)29)26(34)21(15-37-23)31-38(35,36)16-18-4-2-1-3-5-18/h1-12,21,31H,13-16,27H2,(H3,28,29)(H,30,33)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293390
(2-[(3S)-8-Amino-3-[benzylsulfonylamino]-4-oxo-3,4-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccc(N)cc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H28N6O4S2/c27-20-10-11-22-23(12-20)37-15-21(31-38(35,36)16-18-4-2-1-3-5-18)26(34)32(22)14-24(33)30-13-17-6-8-19(9-7-17)25(28)29/h1-12,21,31H,13-16,27H2,(H3,28,29)(H,30,33)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293388
(2-[(3S)-7-Aminomethyl-3-[benzylsulfonylamino]-4-ox...)Show SMILES NCc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1 |r| Show InChI InChI=1S/C27H30N6O4S2/c28-13-20-8-11-24-23(12-20)33(15-25(34)31-14-18-6-9-21(10-7-18)26(29)30)27(35)22(16-38-24)32-39(36,37)17-19-4-2-1-3-5-19/h1-12,22,32H,13-17,28H2,(H3,29,30)(H,31,34)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293388
(2-[(3S)-7-Aminomethyl-3-[benzylsulfonylamino]-4-ox...)Show SMILES NCc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1 |r| Show InChI InChI=1S/C27H30N6O4S2/c28-13-20-8-11-24-23(12-20)33(15-25(34)31-14-18-6-9-21(10-7-18)26(29)30)27(35)22(16-38-24)32-39(36,37)17-19-4-2-1-3-5-19/h1-12,22,32H,13-17,28H2,(H3,29,30)(H,31,34)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293391
(2-[(3S)-7-Amino-3-[benzylsulfonylamino]-4-oxo-3,4-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(N)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H28N6O4S2/c27-20-10-11-23-22(12-20)32(14-24(33)30-13-17-6-8-19(9-7-17)25(28)29)26(34)21(15-37-23)31-38(35,36)16-18-4-2-1-3-5-18/h1-12,21,31H,13-16,27H2,(H3,28,29)(H,30,33)/t21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293386
(CHEMBL554824 | {(3S)-5-[2-({4-[Amino(imino)methyl]...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(CCC(O)=O)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C29H31N5O6S2/c30-28(31)22-10-6-20(7-11-22)15-32-26(35)16-34-24-14-19(9-13-27(36)37)8-12-25(24)41-17-23(29(34)38)33-42(39,40)18-21-4-2-1-3-5-21/h1-8,10-12,14,23,33H,9,13,15-18H2,(H3,30,31)(H,32,35)(H,36,37)/t23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293391
(2-[(3S)-7-Amino-3-[benzylsulfonylamino]-4-oxo-3,4-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(N)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H28N6O4S2/c27-20-10-11-23-22(12-20)32(14-24(33)30-13-17-6-8-19(9-7-17)25(28)29)26(34)21(15-37-23)31-38(35,36)16-18-4-2-1-3-5-18/h1-12,21,31H,13-16,27H2,(H3,28,29)(H,30,33)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293386
(CHEMBL554824 | {(3S)-5-[2-({4-[Amino(imino)methyl]...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(CCC(O)=O)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C29H31N5O6S2/c30-28(31)22-10-6-20(7-11-22)15-32-26(35)16-34-24-14-19(9-13-27(36)37)8-12-25(24)41-17-23(29(34)38)33-42(39,40)18-21-4-2-1-3-5-21/h1-8,10-12,14,23,33H,9,13,15-18H2,(H3,30,31)(H,32,35)(H,36,37)/t23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293385
(2-[(3S)-7-[2-Aminoethyl]-3-[benzylsulfonylamino]-4...)Show SMILES NCCc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1 |r| Show InChI InChI=1S/C28H32N6O4S2/c29-13-12-19-8-11-25-24(14-19)34(16-26(35)32-15-20-6-9-22(10-7-20)27(30)31)28(36)23(17-39-25)33-40(37,38)18-21-4-2-1-3-5-21/h1-11,14,23,33H,12-13,15-18,29H2,(H3,30,31)(H,32,35)/t23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293383
(2-[(3S)-3-[Benzylsulfonylamino]-7-(3-nitrophenyl)-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)-c2cccc(c2)[N+]([O-])=O)cc1 |r| Show InChI InChI=1S/C32H30N6O6S2/c33-31(34)23-11-9-21(10-12-23)17-35-30(39)18-37-28-16-25(24-7-4-8-26(15-24)38(41)42)13-14-29(28)45-19-27(32(37)40)36-46(43,44)20-22-5-2-1-3-6-22/h1-16,27,36H,17-20H2,(H3,33,34)(H,35,39)/t27-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293389
(CHEMBL553237 | {(3S)-5-[2-({4-[Amino(imino)methyl]...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(CC(O)=O)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C28H29N5O6S2/c29-27(30)21-9-6-18(7-10-21)14-31-25(34)15-33-23-12-20(13-26(35)36)8-11-24(23)40-16-22(28(33)37)32-41(38,39)17-19-4-2-1-3-5-19/h1-12,22,32H,13-17H2,(H3,29,30)(H,31,34)(H,35,36)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293382
(2-[(3S)-7-(3-Aminophenyl)-3-[benzylsulfonylamino]-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)-c2cccc(N)c2)cc1 |r| Show InChI InChI=1S/C32H32N6O4S2/c33-26-8-4-7-24(15-26)25-13-14-29-28(16-25)38(18-30(39)36-17-21-9-11-23(12-10-21)31(34)35)32(40)27(19-43-29)37-44(41,42)20-22-5-2-1-3-6-22/h1-16,27,37H,17-20,33H2,(H3,34,35)(H,36,39)/t27-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50293379
((R)-N-(4-carbamimidoylbenzyl)-2-(4-oxo-3-(phenylme...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccccc3SC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H27N5O4S2/c27-25(28)20-12-10-18(11-13-20)14-29-24(32)15-31-22-8-4-5-9-23(22)36-16-21(26(31)33)30-37(34,35)17-19-6-2-1-3-7-19/h1-13,21,30H,14-17H2,(H3,27,28)(H,29,32)/t21-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 10a by spectrometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293401
((3S)-5-[2-([4-[Amino(imino)methyl]benzyl]amino)-2-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)C(O)=O)cc1 |r| Show InChI InChI=1S/C27H27N5O6S2/c28-25(29)19-8-6-17(7-9-19)13-30-24(33)14-32-22-12-20(27(35)36)10-11-23(22)39-15-21(26(32)34)31-40(37,38)16-18-4-2-1-3-5-18/h1-12,21,31H,13-16H2,(H3,28,29)(H,30,33)(H,35,36)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293390
(2-[(3S)-8-Amino-3-[benzylsulfonylamino]-4-oxo-3,4-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccc(N)cc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H28N6O4S2/c27-20-10-11-22-23(12-20)37-15-21(31-38(35,36)16-18-4-2-1-3-5-18)26(34)32(22)14-24(33)30-13-17-6-8-19(9-7-17)25(28)29/h1-12,21,31H,13-16,27H2,(H3,28,29)(H,30,33)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293387
(2-[(3S)-8-Aminomethyl-3-[benzylsulfonylamino]-4-ox...)Show SMILES NCc1ccc2N(CC(=O)NCc3ccc(cc3)C(N)=N)C(=O)[C@@H](CSc2c1)NS(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C27H30N6O4S2/c28-13-20-8-11-23-24(12-20)38-16-22(32-39(36,37)17-19-4-2-1-3-5-19)27(35)33(23)15-25(34)31-14-18-6-9-21(10-7-18)26(29)30/h1-12,22,32H,13-17,28H2,(H3,29,30)(H,31,34)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293383
(2-[(3S)-3-[Benzylsulfonylamino]-7-(3-nitrophenyl)-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)-c2cccc(c2)[N+]([O-])=O)cc1 |r| Show InChI InChI=1S/C32H30N6O6S2/c33-31(34)23-11-9-21(10-12-23)17-35-30(39)18-37-28-16-25(24-7-4-8-26(15-24)38(41)42)13-14-29(28)45-19-27(32(37)40)36-46(43,44)20-22-5-2-1-3-6-22/h1-16,27,36H,17-20H2,(H3,33,34)(H,35,39)/t27-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293385
(2-[(3S)-7-[2-Aminoethyl]-3-[benzylsulfonylamino]-4...)Show SMILES NCCc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1 |r| Show InChI InChI=1S/C28H32N6O4S2/c29-13-12-19-8-11-25-24(14-19)34(16-26(35)32-15-20-6-9-22(10-7-20)27(30)31)28(36)23(17-39-25)33-40(37,38)18-21-4-2-1-3-5-21/h1-11,14,23,33H,12-13,15-18,29H2,(H3,30,31)(H,32,35)/t23-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293382
(2-[(3S)-7-(3-Aminophenyl)-3-[benzylsulfonylamino]-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)-c2cccc(N)c2)cc1 |r| Show InChI InChI=1S/C32H32N6O4S2/c33-26-8-4-7-24(15-26)25-13-14-29-28(16-25)38(18-30(39)36-17-21-9-11-23(12-10-21)31(34)35)32(40)27(19-43-29)37-44(41,42)20-22-5-2-1-3-6-22/h1-16,27,37H,17-20,33H2,(H3,34,35)(H,36,39)/t27-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293390
(2-[(3S)-8-Amino-3-[benzylsulfonylamino]-4-oxo-3,4-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccc(N)cc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H28N6O4S2/c27-20-10-11-22-23(12-20)37-15-21(31-38(35,36)16-18-4-2-1-3-5-18)26(34)32(22)14-24(33)30-13-17-6-8-19(9-7-17)25(28)29/h1-12,21,31H,13-16,27H2,(H3,28,29)(H,30,33)/t21-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293387
(2-[(3S)-8-Aminomethyl-3-[benzylsulfonylamino]-4-ox...)Show SMILES NCc1ccc2N(CC(=O)NCc3ccc(cc3)C(N)=N)C(=O)[C@@H](CSc2c1)NS(=O)(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C27H30N6O4S2/c28-13-20-8-11-23-24(12-20)38-16-22(32-39(36,37)17-19-4-2-1-3-5-19)27(35)33(23)15-25(34)31-14-18-6-9-21(10-7-18)26(29)30/h1-12,22,32H,13-17,28H2,(H3,29,30)(H,31,34)/t22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293388
(2-[(3S)-7-Aminomethyl-3-[benzylsulfonylamino]-4-ox...)Show SMILES NCc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1 |r| Show InChI InChI=1S/C27H30N6O4S2/c28-13-20-8-11-24-23(12-20)33(15-25(34)31-14-18-6-9-21(10-7-18)26(29)30)27(35)22(16-38-24)32-39(36,37)17-19-4-2-1-3-5-19/h1-12,22,32H,13-17,28H2,(H3,29,30)(H,31,34)/t22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293382
(2-[(3S)-7-(3-Aminophenyl)-3-[benzylsulfonylamino]-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)-c2cccc(N)c2)cc1 |r| Show InChI InChI=1S/C32H32N6O4S2/c33-26-8-4-7-24(15-26)25-13-14-29-28(16-25)38(18-30(39)36-17-21-9-11-23(12-10-21)31(34)35)32(40)27(19-43-29)37-44(41,42)20-22-5-2-1-3-6-22/h1-16,27,37H,17-20,33H2,(H3,34,35)(H,36,39)/t27-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293397
(2-[(3S)-3-[Benzylsulfonylamino]-4-oxo-7-phenyl-3,4...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)-c2ccccc2)cc1 |r| Show InChI InChI=1S/C32H31N5O4S2/c33-31(34)25-13-11-22(12-14-25)18-35-30(38)19-37-28-17-26(24-9-5-2-6-10-24)15-16-29(28)42-20-27(32(37)39)36-43(40,41)21-23-7-3-1-4-8-23/h1-17,27,36H,18-21H2,(H3,33,34)(H,35,38)/t27-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293398
(CHEMBL552926 | {(3S)-5-[2-({4-[Amino(imino)methyl]...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccc(CCC(O)=O)cc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C29H31N5O6S2/c30-28(31)22-10-6-20(7-11-22)15-32-26(35)16-34-24-12-8-19(9-13-27(36)37)14-25(24)41-17-23(29(34)38)33-42(39,40)18-21-4-2-1-3-5-21/h1-8,10-12,14,23,33H,9,13,15-18H2,(H3,30,31)(H,32,35)(H,36,37)/t23-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293399
(CHEMBL554142 | {(3S)-5-[2-({4-[Amino(imino)methyl]...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccc(CC(O)=O)cc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C28H29N5O6S2/c29-27(30)21-9-6-18(7-10-21)14-31-25(34)15-33-23-11-8-20(13-26(35)36)12-24(23)40-16-22(28(33)37)32-41(38,39)17-19-4-2-1-3-5-19/h1-12,22,32H,13-17H2,(H3,29,30)(H,31,34)(H,35,36)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293408
((S)-2-(5-(2-(4-carbamimidoylbenzylamino)-2-oxoethy...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccccc3SC[C@@H](NCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C21H23N5O4S/c22-20(23)14-7-5-13(6-8-14)9-25-18(27)11-26-16-3-1-2-4-17(16)31-12-15(21(26)30)24-10-19(28)29/h1-8,15,24H,9-12H2,(H3,22,23)(H,25,27)(H,28,29)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293377
((R)-N-(4-carbamimidoylbenzyl)-3-(4-oxo-3-(phenylme...)Show SMILES NC(=N)c1ccc(CNC(=O)CCN2c3ccccc3SC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C27H29N5O4S2/c28-26(29)21-12-10-19(11-13-21)16-30-25(33)14-15-32-23-8-4-5-9-24(23)37-17-22(27(32)34)31-38(35,36)18-20-6-2-1-3-7-20/h1-13,22,31H,14-18H2,(H3,28,29)(H,30,33)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293381
((R)-2-(3-amino-4-oxo-3,4-dihydrobenzo[b][1,4]thiaz...)Show SMILES N[C@H]1CSc2ccccc2N(CC(=O)NCc2ccc(cc2)C(N)=N)C1=O |r| Show InChI InChI=1S/C19H21N5O2S/c20-14-11-27-16-4-2-1-3-15(16)24(19(14)26)10-17(25)23-9-12-5-7-13(8-6-12)18(21)22/h1-8,14H,9-11,20H2,(H3,21,22)(H,23,25)/t14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293375
((R)-4-(5-(2-(4-carbamimidoylbenzylamino)-2-oxoethy...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccccc3SC[C@H](NC(=O)CCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C23H25N5O5S/c24-22(25)15-7-5-14(6-8-15)11-26-20(30)12-28-17-3-1-2-4-18(17)34-13-16(23(28)33)27-19(29)9-10-21(31)32/h1-8,16H,9-13H2,(H3,24,25)(H,26,30)(H,27,29)(H,31,32)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293379
((R)-N-(4-carbamimidoylbenzyl)-2-(4-oxo-3-(phenylme...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccccc3SC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H27N5O4S2/c27-25(28)20-12-10-18(11-13-20)14-29-24(32)15-31-22-8-4-5-9-23(22)36-16-21(26(31)33)30-37(34,35)17-19-6-2-1-3-7-19/h1-13,21,30H,14-17H2,(H3,27,28)(H,29,32)/t21-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293406
((S)-N-(5-(2-(4-carbamimidoylbenzylamino)-2-oxoethy...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccccc3SC[C@@H](NC(=O)C(c3ccccc3)c3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C33H31N5O3S/c34-31(35)25-17-15-22(16-18-25)19-36-29(39)20-38-27-13-7-8-14-28(27)42-21-26(33(38)41)37-32(40)30(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-18,26,30H,19-21H2,(H3,34,35)(H,36,39)(H,37,40)/t26-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293404
((S)-N-((6-amino-2-methylpyridin-3-yl)methyl)-3-(4-...)Show SMILES Cc1nc(N)ccc1CNC(=O)CCN1c2ccccc2SC[C@@H](NS(=O)(=O)Cc2ccccc2)C1=O |r| Show InChI InChI=1S/C26H29N5O4S2/c1-18-20(11-12-24(27)29-18)15-28-25(32)13-14-31-22-9-5-6-10-23(22)36-16-21(26(31)33)30-37(34,35)17-19-7-3-2-4-8-19/h2-12,21,30H,13-17H2,1H3,(H2,27,29)(H,28,32)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293400
((3S)-5-[2-([4-[Amino(imino)methyl]benzyl]amino)-2-...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccc(cc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)C(O)=O)cc1 |r| Show InChI InChI=1S/C27H27N5O6S2/c28-25(29)19-8-6-17(7-9-19)13-30-24(33)14-32-22-11-10-20(27(35)36)12-23(22)39-15-21(26(32)34)31-40(37,38)16-18-4-2-1-3-5-18/h1-12,21,31H,13-16H2,(H3,28,29)(H,30,33)(H,35,36)/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293396
((R)-2-(5-(3-(4-carbamimidoylbenzylamino)-3-oxoprop...)Show SMILES NC(=N)c1ccc(CNC(=O)CCN2c3ccccc3SC[C@H](NCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C22H25N5O4S/c23-21(24)15-7-5-14(6-8-15)11-26-19(28)9-10-27-17-3-1-2-4-18(17)32-13-16(22(27)31)25-12-20(29)30/h1-8,16,25H,9-13H2,(H3,23,24)(H,26,28)(H,29,30)/t16-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293384
(2-Amino-3-{(3S)-5-[2-({4-[amino(imino)methyl]benzy...)Show SMILES NC(Cc1ccc2SC[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N(CC(=O)NCc3ccc(cc3)C(N)=N)c2c1)C(O)=O |r| Show InChI InChI=1S/C29H32N6O6S2/c30-22(29(38)39)12-20-8-11-25-24(13-20)35(15-26(36)33-14-18-6-9-21(10-7-18)27(31)32)28(37)23(16-42-25)34-43(40,41)17-19-4-2-1-3-5-19/h1-11,13,22-23,34H,12,14-17,30H2,(H3,31,32)(H,33,36)(H,38,39)/t22?,23-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293405
((S)-N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(4-...)Show SMILES Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@@H](NS(=O)(=O)Cc2ccccc2)C1=O |r| Show InChI InChI=1S/C25H27N5O4S2/c1-17-19(11-12-23(26)28-17)13-27-24(31)14-30-21-9-5-6-10-22(21)35-15-20(25(30)32)29-36(33,34)16-18-7-3-2-4-8-18/h2-12,20,29H,13-16H2,1H3,(H2,26,28)(H,27,31)/t20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293403
((S)-2-(5-(2-((6-amino-2-methylpyridin-3-yl)methyla...)Show SMILES Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@@H](NCC(O)=O)C1=O |r| Show InChI InChI=1S/C20H23N5O4S/c1-12-13(6-7-17(21)24-12)8-23-18(26)10-25-15-4-2-3-5-16(15)30-11-14(20(25)29)22-9-19(27)28/h2-7,14,22H,8-11H2,1H3,(H2,21,24)(H,23,26)(H,27,28)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293373
((R)-4-(5-(3-(4-carbamimidoylbenzylamino)-3-oxoprop...)Show SMILES NC(=N)c1ccc(CNC(=O)CCN2c3ccccc3SC[C@H](NC(=O)CCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C24H27N5O5S/c25-23(26)16-7-5-15(6-8-16)13-27-20(30)11-12-29-18-3-1-2-4-19(18)35-14-17(24(29)34)28-21(31)9-10-22(32)33/h1-8,17H,9-14H2,(H3,25,26)(H,27,30)(H,28,31)(H,32,33)/t17-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293389
(CHEMBL553237 | {(3S)-5-[2-({4-[Amino(imino)methyl]...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(CC(O)=O)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C28H29N5O6S2/c29-27(30)21-9-6-18(7-10-21)14-31-25(34)15-33-23-12-20(13-26(35)36)8-11-24(23)40-16-22(28(33)37)32-41(38,39)17-19-4-2-1-3-5-19/h1-12,22,32H,13-17H2,(H3,29,30)(H,31,34)(H,35,36)/t22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293386
(CHEMBL554824 | {(3S)-5-[2-({4-[Amino(imino)methyl]...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3cc(CCC(O)=O)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C29H31N5O6S2/c30-28(31)22-10-6-20(7-11-22)15-32-26(35)16-34-24-14-19(9-13-27(36)37)8-12-25(24)41-17-23(29(34)38)33-42(39,40)18-21-4-2-1-3-5-21/h1-8,10-12,14,23,33H,9,13,15-18H2,(H3,30,31)(H,32,35)(H,36,37)/t23-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293402
((S)-2-(5-(3-((6-amino-2-methylpyridin-3-yl)methyla...)Show SMILES Cc1nc(N)ccc1CNC(=O)CCN1c2ccccc2SC[C@@H](NCC(O)=O)C1=O |r| Show InChI InChI=1S/C21H25N5O4S/c1-13-14(6-7-18(22)25-13)10-24-19(27)8-9-26-16-4-2-3-5-17(16)31-12-15(21(26)30)23-11-20(28)29/h2-7,15,23H,8-12H2,1H3,(H2,22,25)(H,24,27)(H,28,29)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293371
((R)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@H]1CSc2ccccc2N(CC(=O)NCc2ccc(cc2)C(N)=N)C1=O |r| Show InChI InChI=1S/C21H23N5O3S/c1-13(27)25-16-12-30-18-5-3-2-4-17(18)26(21(16)29)11-19(28)24-10-14-6-8-15(9-7-14)20(22)23/h2-9,16H,10-12H2,1H3,(H3,22,23)(H,24,28)(H,25,27)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293379
((R)-N-(4-carbamimidoylbenzyl)-2-(4-oxo-3-(phenylme...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccccc3SC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C26H27N5O4S2/c27-25(28)20-12-10-18(11-13-20)14-29-24(32)15-31-22-8-4-5-9-23(22)36-16-21(26(31)33)30-37(34,35)17-19-6-2-1-3-7-19/h1-13,21,30H,14-17H2,(H3,27,28)(H,29,32)/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293374
((S)-4-(5-(3-(4-carbamimidoylbenzylamino)-3-oxoprop...)Show SMILES NC(=N)c1ccc(CNC(=O)CCN2c3ccccc3SC[C@@H](NC(=O)CCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C24H27N5O5S/c25-23(26)16-7-5-15(6-8-16)13-27-20(30)11-12-29-18-3-1-2-4-19(18)35-14-17(24(29)34)28-21(31)9-10-22(32)33/h1-8,17H,9-14H2,(H3,25,26)(H,27,30)(H,28,31)(H,32,33)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293378
((S)-N-(4-carbamimidoylbenzyl)-3-(4-oxo-3-(phenylme...)Show SMILES NC(=N)c1ccc(CNC(=O)CCN2c3ccccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1 |r| Show InChI InChI=1S/C27H29N5O4S2/c28-26(29)21-12-10-19(11-13-21)16-30-25(33)14-15-32-23-8-4-5-9-24(23)37-17-22(27(32)34)31-38(35,36)18-20-6-2-1-3-7-20/h1-13,22,31H,14-18H2,(H3,28,29)(H,30,33)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293381
((R)-2-(3-amino-4-oxo-3,4-dihydrobenzo[b][1,4]thiaz...)Show SMILES N[C@H]1CSc2ccccc2N(CC(=O)NCc2ccc(cc2)C(N)=N)C1=O |r| Show InChI InChI=1S/C19H21N5O2S/c20-14-11-27-16-4-2-1-3-15(16)24(19(14)26)10-17(25)23-9-12-5-7-13(8-6-12)18(21)22/h1-8,14H,9-11,20H2,(H3,21,22)(H,23,25)/t14-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293395
((S)-N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(3-...)Show SMILES Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@@H](N)C1=O |r| Show InChI InChI=1S/C18H21N5O2S/c1-11-12(6-7-16(20)22-11)8-21-17(24)9-23-14-4-2-3-5-15(14)26-10-13(19)18(23)25/h2-7,13H,8-10,19H2,1H3,(H2,20,22)(H,21,24)/t13-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293394
((R)-N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(3-...)Show SMILES Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@H](N)C1=O |r| Show InChI InChI=1S/C18H21N5O2S/c1-11-12(6-7-16(20)22-11)8-21-17(24)9-23-14-4-2-3-5-15(14)26-10-13(19)18(23)25/h2-7,13H,8-10,19H2,1H3,(H2,20,22)(H,21,24)/t13-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293372
((S)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@@H]1CSc2ccccc2N(CC(=O)NCc2ccc(cc2)C(N)=N)C1=O |r| Show InChI InChI=1S/C21H23N5O3S/c1-13(27)25-16-12-30-18-5-3-2-4-17(18)26(21(16)29)11-19(28)24-10-14-6-8-15(9-7-14)20(22)23/h2-9,16H,10-12H2,1H3,(H3,22,23)(H,24,28)(H,25,27)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293407
((S)-2-(5-(3-(4-carbamimidoylbenzylamino)-3-oxoprop...)Show SMILES NC(=N)c1ccc(CNC(=O)CCN2c3ccccc3SC[C@@H](NCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C22H25N5O4S/c23-21(24)15-7-5-14(6-8-15)11-26-19(28)9-10-27-17-3-1-2-4-18(17)32-13-16(22(27)31)25-12-20(29)30/h1-8,16,25H,9-13H2,(H3,23,24)(H,26,28)(H,29,30)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293371
((R)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@H]1CSc2ccccc2N(CC(=O)NCc2ccc(cc2)C(N)=N)C1=O |r| Show InChI InChI=1S/C21H23N5O3S/c1-13(27)25-16-12-30-18-5-3-2-4-17(18)26(21(16)29)11-19(28)24-10-14-6-8-15(9-7-14)20(22)23/h2-9,16H,10-12H2,1H3,(H3,22,23)(H,24,28)(H,25,27)/t16-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293392
((R)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@H]1CSc2ccccc2N(CC(=O)NCc2ccc(N)nc2C)C1=O |r| Show InChI InChI=1S/C20H23N5O3S/c1-12-14(7-8-18(21)23-12)9-22-19(27)10-25-16-5-3-4-6-17(16)29-11-15(20(25)28)24-13(2)26/h3-8,15H,9-11H2,1-2H3,(H2,21,23)(H,22,27)(H,24,26)/t15-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293393
((S)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@@H]1CSc2ccccc2N(CC(=O)NCc2ccc(N)nc2C)C1=O |r| Show InChI InChI=1S/C20H23N5O3S/c1-12-14(7-8-18(21)23-12)9-22-19(27)10-25-16-5-3-4-6-17(16)29-11-15(20(25)28)24-13(2)26/h3-8,15H,9-11H2,1-2H3,(H2,21,23)(H,22,27)(H,24,26)/t15-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293373
((R)-4-(5-(3-(4-carbamimidoylbenzylamino)-3-oxoprop...)Show SMILES NC(=N)c1ccc(CNC(=O)CCN2c3ccccc3SC[C@H](NC(=O)CCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C24H27N5O5S/c25-23(26)16-7-5-15(6-8-16)13-27-20(30)11-12-29-18-3-1-2-4-19(18)35-14-17(24(29)34)28-21(31)9-10-22(32)33/h1-8,17H,9-14H2,(H3,25,26)(H,27,30)(H,28,31)(H,32,33)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293409
((R)-3-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@H]1CSc2ccccc2N(CCC(=O)NCc2ccc(cc2)C(N)=N)C1=O |r| Show InChI InChI=1S/C22H25N5O3S/c1-14(28)26-17-13-31-19-5-3-2-4-18(19)27(22(17)30)11-10-20(29)25-12-15-6-8-16(9-7-15)21(23)24/h2-9,17H,10-13H2,1H3,(H3,23,24)(H,25,29)(H,26,28)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.68E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293370
((S)-3-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@@H]1CSc2ccccc2N(CCC(=O)NCc2ccc(cc2)C(N)=N)C1=O |r| Show InChI InChI=1S/C22H25N5O3S/c1-14(28)26-17-13-31-19-5-3-2-4-18(19)27(22(17)30)11-10-20(29)25-12-15-6-8-16(9-7-15)21(23)24/h2-9,17H,10-13H2,1H3,(H3,23,24)(H,25,29)(H,26,28)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50293375
((R)-4-(5-(2-(4-carbamimidoylbenzylamino)-2-oxoethy...)Show SMILES NC(=N)c1ccc(CNC(=O)CN2c3ccccc3SC[C@H](NC(=O)CCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C23H25N5O5S/c24-22(25)15-7-5-14(6-8-15)11-26-20(30)12-28-17-3-1-2-4-18(17)34-13-16(23(28)33)27-19(29)9-10-21(31)32/h1-8,16H,9-13H2,(H3,24,25)(H,26,30)(H,27,29)(H,31,32)/t16-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human factor 2a by spectrophotometry |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293395
((S)-N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(3-...)Show SMILES Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@@H](N)C1=O |r| Show InChI InChI=1S/C18H21N5O2S/c1-11-12(6-7-16(20)22-11)8-21-17(24)9-23-14-4-2-3-5-15(14)26-10-13(19)18(23)25/h2-7,13H,8-10,19H2,1H3,(H2,20,22)(H,21,24)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293394
((R)-N-((6-amino-2-methylpyridin-3-yl)methyl)-2-(3-...)Show SMILES Cc1nc(N)ccc1CNC(=O)CN1c2ccccc2SC[C@H](N)C1=O |r| Show InChI InChI=1S/C18H21N5O2S/c1-11-12(6-7-16(20)22-11)8-21-17(24)9-23-14-4-2-3-5-15(14)26-10-13(19)18(23)25/h2-7,13H,8-10,19H2,1H3,(H2,20,22)(H,21,24)/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293392
((R)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@H]1CSc2ccccc2N(CC(=O)NCc2ccc(N)nc2C)C1=O |r| Show InChI InChI=1S/C20H23N5O3S/c1-12-14(7-8-18(21)23-12)9-22-19(27)10-25-16-5-3-4-6-17(16)29-11-15(20(25)28)24-13(2)26/h3-8,15H,9-11H2,1-2H3,(H2,21,23)(H,22,27)(H,24,26)/t15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293393
((S)-2-(3-acetamido-4-oxo-3,4-dihydrobenzo[b][1,4]t...)Show SMILES CC(=O)N[C@@H]1CSc2ccccc2N(CC(=O)NCc2ccc(N)nc2C)C1=O |r| Show InChI InChI=1S/C20H23N5O3S/c1-12-14(7-8-18(21)23-12)9-22-19(27)10-25-16-5-3-4-6-17(16)29-11-15(20(25)28)24-13(2)26/h3-8,15H,9-11H2,1-2H3,(H2,21,23)(H,22,27)(H,24,26)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
Tissue factor
(Homo sapiens (Human)) | BDBM50293396
((R)-2-(5-(3-(4-carbamimidoylbenzylamino)-3-oxoprop...)Show SMILES NC(=N)c1ccc(CNC(=O)CCN2c3ccccc3SC[C@H](NCC(O)=O)C2=O)cc1 |r| Show InChI InChI=1S/C22H25N5O4S/c23-21(24)15-7-5-14(6-8-15)11-26-19(28)9-10-27-17-3-1-2-4-18(17)32-13-16(22(27)31)25-12-20(29)30/h1-8,16,25H,9-13H2,(H3,23,24)(H,26,28)(H,29,30)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1
Curated by ChEMBL
| Assay Description
Inhibition of human tissue factor/factor 7a |
Bioorg Med Chem Lett 19: 1386-91 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.039
BindingDB Entry DOI: 10.7270/Q2G73DRB |
More data for this
Ligand-Target Pair | |
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