Found 116 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248275
(CHEMBL474751 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ncccc4c3)cccc12 Show InChI InChI=1S/C27H19F2N3O4S/c1-32-16-18(7-12-26(33)31-37(34,35)20-9-10-21(28)22(29)15-20)27-24(32)5-2-6-25(27)36-19-8-11-23-17(14-19)4-3-13-30-23/h2-16H,1H3,(H,31,33)/b12-7+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248277
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248330
(3-(4-(4-chlorophenoxy)-1-methyl-1H-indol-3-yl)-N-(...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(24-20(30)3-2-4-21(24)34-16-8-6-15(25)7-9-16)5-10-23(31)29-35(32,33)22-12-18(27)17(26)11-19(22)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248278
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-17(28)16(27)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(25)9-15(20)26/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248073
(CHEMBL463816 | N-(2,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)cc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)26-13-11-21(29)16-23(26)30)28-24(32)7-4-8-25(28)36-22-12-9-18-5-2-3-6-19(18)15-22/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248331
(3-(4-(3,4-difluorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(F)c3)cccc12 Show InChI InChI=1S/C24H15F5N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248216
(CHEMBL472957 | N-(3,4-difluorophenylsulfonyl)-3-(4...)Show SMILES COc1cccc(Oc2cccc3n(C)cc(\C=C\C(=O)NS(=O)(=O)c4ccc(F)c(F)c4)c23)c1 Show InChI InChI=1S/C25H20F2N2O5S/c1-29-15-16(9-12-24(30)28-35(31,32)19-10-11-20(26)21(27)14-19)25-22(29)7-4-8-23(25)34-18-6-3-5-17(13-18)33-2/h3-15H,1-2H3,(H,28,30)/b12-9+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248393
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-16(27)15(26)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(25)9-17(20)28/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247941
(CHEMBL490693 | N-(4,5-dichlorothiophen-2-ylsulfony...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(Cl)c(Cl)s2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C26H18Cl2N2O4S2/c1-30-15-18(10-12-23(31)29-36(32,33)24-14-20(27)26(28)35-24)25-21(30)7-4-8-22(25)34-19-11-9-16-5-2-3-6-17(16)13-19/h2-15H,1H3,(H,29,31)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248170
(3-(4-(3,4-difluorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(F)c3)cccc12 Show InChI InChI=1S/C24H16F4N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-18(26)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)19(27)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248137
(3-(1-methyl-4-(naphthalen-2-yloxy)-1H-indol-3-yl)-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H17F5N2O4S/c1-35-14-17(10-12-21(36)34-40(37,38)28-26(32)24(30)23(29)25(31)27(28)33)22-19(35)7-4-8-20(22)39-18-11-9-15-5-2-3-6-16(15)13-18/h2-14H,1H3,(H,34,36)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248395
(3-(4-(3-methoxyphenoxy)-1-methyl-1H-indol-3-yl)-N-...)Show SMILES COc1cccc(Oc2cccc3n(C)cc(\C=C\C(=O)NS(=O)(=O)c4cc(F)c(F)cc4F)c23)c1 Show InChI InChI=1S/C25H19F3N2O5S/c1-30-14-15(9-10-24(31)29-36(32,33)23-13-19(27)18(26)12-20(23)28)25-21(30)7-4-8-22(25)35-17-6-3-5-16(11-17)34-2/h3-14H,1-2H3,(H,29,31)/b10-9+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248107
(CHEMBL461807 | N-(2,6-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2c(F)cccc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(13-15-26(33)31-37(34,35)28-22(29)8-4-9-23(28)30)27-24(32)10-5-11-25(27)36-21-14-12-18-6-2-3-7-19(18)16-21/h2-17H,1H3,(H,31,33)/b15-13+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248276
(CHEMBL516394 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3cnc4ccccc4n3)cccc12 Show InChI InChI=1S/C26H18F2N4O4S/c1-32-15-16(9-12-24(33)31-37(34,35)17-10-11-18(27)19(28)13-17)26-22(32)7-4-8-23(26)36-25-14-29-20-5-2-3-6-21(20)30-25/h2-15H,1H3,(H,31,33)/b12-9+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248074
(CHEMBL464618 | N-(2,5-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)ccc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)26-16-21(29)11-13-23(26)30)28-24(32)7-4-8-25(28)36-22-12-9-18-5-2-3-6-19(18)15-22/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248392
(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(F)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248448
(3-(1-methyl-4-(quinoxalin-2-yloxy)-1H-indol-3-yl)-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3cnc4ccccc4n3)cccc12 Show InChI InChI=1S/C26H17F3N4O4S/c1-33-14-15(9-10-24(34)32-38(35,36)23-12-17(28)16(27)11-18(23)29)26-21(33)7-4-8-22(26)37-25-13-30-19-5-2-3-6-20(19)31-25/h2-14H,1H3,(H,32,34)/b10-9+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248214
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-17(26)18(27)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-19(21)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247942
(CHEMBL521609 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248447
(3-(1-methyl-4-(quinolin-6-yloxy)-1H-indol-3-yl)-N-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc4ncccc4c3)cccc12 Show InChI InChI=1S/C27H18F3N3O4S/c1-33-15-17(7-10-26(34)32-38(35,36)25-14-20(29)19(28)13-21(25)30)27-23(33)5-2-6-24(27)37-18-8-9-22-16(12-18)4-3-11-31-22/h2-15H,1H3,(H,32,34)/b10-7+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248072
(CHEMBL463815 | N-(3,5-dichlorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(Cl)cc(Cl)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20Cl2N2O4S/c1-32-17-20(10-12-27(33)31-37(34,35)24-15-21(29)14-22(30)16-24)28-25(32)7-4-8-26(28)36-23-11-9-18-5-2-3-6-19(18)13-23/h2-17H,1H3,(H,31,33)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247966
(3-(1-methyl-4-(naphthalen-2-yloxy)-1H-indol-3-yl)-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H19F3N2O4S/c1-33-16-19(10-12-27(34)32-38(35,36)26-15-22(30)21(29)14-23(26)31)28-24(33)7-4-8-25(28)37-20-11-9-17-5-2-3-6-18(17)13-20/h2-16H,1H3,(H,32,34)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248026
(CHEMBL459688 | N-(4-fluorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)cc2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21FN2O4S/c1-31-18-21(10-16-27(32)30-36(33,34)24-14-11-22(29)12-15-24)28-25(31)7-4-8-26(28)35-23-13-9-19-5-2-3-6-20(19)17-23/h2-18H,1H3,(H,30,32)/b16-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248333
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-16(26)15(25)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248028
(CHEMBL460322 | N-(3,4-dichlorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20Cl2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11.8 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248168
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-17(21)26/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11.8 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248110
(CHEMBL461980 | N-(2-fluorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccccc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21FN2O4S/c1-31-18-21(14-16-27(32)30-36(33,34)26-12-5-4-9-23(26)29)28-24(31)10-6-11-25(28)35-22-15-13-19-7-2-3-8-20(19)17-22/h2-18H,1H3,(H,30,32)/b16-14+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11.9 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247939
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)18(26)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 12.4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248215
(3-(4-(2-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)cc3Cl)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(26)11-17(21)25/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13.8 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247940
(CHEMBL490692 | N-(3-chlorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cccc(Cl)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21ClN2O4S/c1-31-18-21(13-15-27(32)30-36(33,34)24-9-4-8-22(29)17-24)28-25(31)10-5-11-26(28)35-23-14-12-19-6-2-3-7-20(19)16-23/h2-18H,1H3,(H,30,32)/b15-13+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 15.7 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247942
(CHEMBL521609 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 15.9 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248278
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-17(28)16(27)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(25)9-15(20)26/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 16.7 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248109
(CHEMBL461979 | N-(3-fluorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cccc(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21FN2O4S/c1-31-18-21(13-15-27(32)30-36(33,34)24-9-4-8-22(29)17-24)28-25(31)10-5-11-26(28)35-23-14-12-19-6-2-3-7-20(19)16-23/h2-18H,1H3,(H,30,32)/b15-13+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17.5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248394
(3-(4-(2-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)cc3Cl)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-17(28)16(27)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(26)9-15(20)25/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18.1 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248027
(CHEMBL460321 | N-(2-chlorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccccc2Cl)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21ClN2O4S/c1-31-18-21(14-16-27(32)30-36(33,34)26-12-5-4-9-23(26)29)28-24(31)10-6-11-25(28)35-22-15-13-19-7-2-3-8-20(19)17-22/h2-18H,1H3,(H,30,32)/b16-14+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18.4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248171
(3-(4-(2,4-difluorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)cc3F)cccc12 Show InChI InChI=1S/C24H16F4N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-17(26)18(27)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-19(21)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18.5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248135
(CHEMBL464411 | N-(4-chlorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21ClN2O4S/c1-31-18-21(10-16-27(32)30-36(33,34)24-14-11-22(29)12-15-24)28-25(31)7-4-8-26(28)35-23-13-9-19-5-2-3-6-20(19)17-23/h2-18H,1H3,(H,30,32)/b16-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 21.9 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248213
(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(F)c3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-18(26)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)19(27)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23.4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248168
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-17(21)26/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23.7 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248583
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-18(26)17(25)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248169
(3-(4-(4-chlorophenoxy)-1-methyl-1H-indol-3-yl)-N-(...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3)cccc12 Show InChI InChI=1S/C24H17ClF2N2O4S/c1-29-14-15(5-12-23(30)28-34(31,32)18-10-11-19(26)20(27)13-18)24-21(29)3-2-4-22(24)33-17-8-6-16(25)7-9-17/h2-14H,1H3,(H,28,30)/b12-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 27.3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247966
(3-(1-methyl-4-(naphthalen-2-yloxy)-1H-indol-3-yl)-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H19F3N2O4S/c1-33-16-19(10-12-27(34)32-38(35,36)26-15-22(30)21(29)14-23(26)31)28-24(33)7-4-8-25(28)37-20-11-9-17-5-2-3-6-18(17)13-20/h2-16H,1H3,(H,32,34)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247940
(CHEMBL490692 | N-(3-chlorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cccc(Cl)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21ClN2O4S/c1-31-18-21(13-15-27(32)30-36(33,34)24-9-4-8-22(29)17-24)28-25(31)10-5-11-26(28)35-23-14-12-19-6-2-3-7-20(19)16-23/h2-18H,1H3,(H,30,32)/b15-13+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248108
(CHEMBL517282 | N-(3,5-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)cc(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-12-27(33)31-37(34,35)24-15-21(29)14-22(30)16-24)28-25(32)7-4-8-26(28)36-23-11-9-18-5-2-3-6-19(18)13-23/h2-17H,1H3,(H,31,33)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 44.9 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248277
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 45.2 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247939
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)18(26)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50.8 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248392
(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(F)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 53.9 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248029
(CHEMBL516789 | N-(2,4-dichlorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(Cl)cc2Cl)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20Cl2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)26-13-11-21(29)16-23(26)30)28-24(32)7-4-8-25(28)36-22-12-9-18-5-2-3-6-19(18)15-22/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 54.1 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248333
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-16(26)15(25)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 61.1 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248583
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-18(26)17(25)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 81.5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248332
(3-(4-(2,4-difluorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)cc3F)cccc12 Show InChI InChI=1S/C24H15F5N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-16(27)15(26)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(25)9-17(20)28/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 84.8 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50247941
(CHEMBL490693 | N-(4,5-dichlorothiophen-2-ylsulfony...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(Cl)c(Cl)s2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C26H18Cl2N2O4S2/c1-30-15-18(10-12-23(31)29-36(32,33)24-14-20(27)26(28)35-24)25-21(30)7-4-8-22(25)34-19-11-9-16-5-2-3-6-17(16)13-19/h2-15H,1H3,(H,29,31)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 89.6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248028
(CHEMBL460322 | N-(3,4-dichlorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20Cl2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 92.9 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248136
(CHEMBL518522 | N-(4-methoxyphenylsulfonyl)-3-(1-me...)Show SMILES COc1ccc(cc1)S(=O)(=O)NC(=O)\C=C\c1cn(C)c2cccc(Oc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C29H24N2O5S/c1-31-19-22(11-17-28(32)30-37(33,34)25-15-13-23(35-2)14-16-25)29-26(31)8-5-9-27(29)36-24-12-10-20-6-3-4-7-21(20)18-24/h3-19H,1-2H3,(H,30,32)/b17-11+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 101 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal buffer |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248073
(CHEMBL463816 | N-(2,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)cc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)26-13-11-21(29)16-23(26)30)28-24(32)7-4-8-25(28)36-22-12-9-18-5-2-3-6-19(18)15-22/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248109
(CHEMBL461979 | N-(3-fluorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cccc(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21FN2O4S/c1-31-18-21(13-15-27(32)30-36(33,34)24-9-4-8-22(29)17-24)28-25(31)10-5-11-26(28)35-23-14-12-19-6-2-3-7-20(19)16-23/h2-18H,1H3,(H,30,32)/b15-13+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248214
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-17(26)18(27)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-19(21)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248448
(3-(1-methyl-4-(quinoxalin-2-yloxy)-1H-indol-3-yl)-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3cnc4ccccc4n3)cccc12 Show InChI InChI=1S/C26H17F3N4O4S/c1-33-14-15(9-10-24(34)32-38(35,36)23-12-17(28)16(27)11-18(23)29)26-21(33)7-4-8-22(26)37-25-13-30-19-5-2-3-6-20(19)31-25/h2-14H,1H3,(H,32,34)/b10-9+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248275
(CHEMBL474751 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ncccc4c3)cccc12 Show InChI InChI=1S/C27H19F2N3O4S/c1-32-16-18(7-12-26(33)31-37(34,35)20-9-10-21(28)22(29)15-20)27-24(32)5-2-6-25(27)36-19-8-11-23-17(14-19)4-3-13-30-23/h2-16H,1H3,(H,31,33)/b12-7+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248215
(3-(4-(2-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)cc3Cl)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(26)11-17(21)25/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248393
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-16(27)15(26)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(25)9-17(20)28/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 156 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248108
(CHEMBL517282 | N-(3,5-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)cc(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-12-27(33)31-37(34,35)24-15-21(29)14-22(30)16-24)28-25(32)7-4-8-26(28)36-23-11-9-18-5-2-3-6-19(18)13-23/h2-17H,1H3,(H,31,33)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 157 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248074
(CHEMBL464618 | N-(2,5-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)ccc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)26-16-21(29)11-13-23(26)30)28-24(32)7-4-8-25(28)36-22-12-9-18-5-2-3-6-19(18)15-22/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 157 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248447
(3-(1-methyl-4-(quinolin-6-yloxy)-1H-indol-3-yl)-N-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc4ncccc4c3)cccc12 Show InChI InChI=1S/C27H18F3N3O4S/c1-33-15-17(7-10-26(34)32-38(35,36)25-14-20(29)19(28)13-21(25)30)27-23(33)5-2-6-24(27)37-18-8-9-22-16(12-18)4-3-11-31-22/h2-15H,1H3,(H,32,34)/b10-7+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 168 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248026
(CHEMBL459688 | N-(4-fluorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)cc2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21FN2O4S/c1-31-18-21(10-16-27(32)30-36(33,34)24-14-11-22(29)12-15-24)28-25(31)7-4-8-26(28)35-23-13-9-19-5-2-3-6-20(19)17-23/h2-18H,1H3,(H,30,32)/b16-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248170
(3-(4-(3,4-difluorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(F)c3)cccc12 Show InChI InChI=1S/C24H16F4N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-18(26)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)19(27)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 196 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248331
(3-(4-(3,4-difluorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(F)c3)cccc12 Show InChI InChI=1S/C24H15F5N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248276
(CHEMBL516394 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3cnc4ccccc4n3)cccc12 Show InChI InChI=1S/C26H18F2N4O4S/c1-32-15-16(9-12-24(33)31-37(34,35)17-10-11-18(27)19(28)13-17)26-22(32)7-4-8-23(26)36-25-14-29-20-5-2-3-6-21(20)30-25/h2-15H,1H3,(H,31,33)/b12-9+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 217 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248394
(3-(4-(2-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)cc3Cl)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-17(28)16(27)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(26)9-15(20)25/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248072
(CHEMBL463815 | N-(3,5-dichlorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(Cl)cc(Cl)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20Cl2N2O4S/c1-32-17-20(10-12-27(33)31-37(34,35)24-15-21(29)14-22(30)16-24)28-25(32)7-4-8-26(28)36-23-11-9-18-5-2-3-6-19(18)13-23/h2-17H,1H3,(H,31,33)/b12-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 321 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248330
(3-(4-(4-chlorophenoxy)-1-methyl-1H-indol-3-yl)-N-(...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(24-20(30)3-2-4-21(24)34-16-8-6-15(25)7-9-16)5-10-23(31)29-35(32,33)22-12-18(27)17(26)11-19(22)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 393 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248213
(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(F)c3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-18(26)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)19(27)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 612 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248110
(CHEMBL461980 | N-(2-fluorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccccc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21FN2O4S/c1-31-18-21(14-16-27(32)30-36(33,34)26-12-5-4-9-23(26)29)28-24(31)10-6-11-25(28)35-22-15-13-19-7-2-3-8-20(19)17-22/h2-18H,1H3,(H,30,32)/b16-14+ | PDB
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UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 646 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248107
(CHEMBL461807 | N-(2,6-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2c(F)cccc2F)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(13-15-26(33)31-37(34,35)28-22(29)8-4-9-23(28)30)27-24(32)10-5-11-25(27)36-21-14-12-18-6-2-3-7-19(18)16-21/h2-17H,1H3,(H,31,33)/b15-13+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248169
(3-(4-(4-chlorophenoxy)-1-methyl-1H-indol-3-yl)-N-(...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3)cccc12 Show InChI InChI=1S/C24H17ClF2N2O4S/c1-29-14-15(5-12-23(30)28-34(31,32)18-10-11-19(26)20(27)13-18)24-21(29)3-2-4-22(24)33-17-8-6-16(25)7-9-17/h2-14H,1H3,(H,28,30)/b12-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 776 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248135
(CHEMBL464411 | N-(4-chlorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21ClN2O4S/c1-31-18-21(10-16-27(32)30-36(33,34)24-14-11-22(29)12-15-24)28-25(31)7-4-8-26(28)35-23-13-9-19-5-2-3-6-20(19)17-23/h2-18H,1H3,(H,30,32)/b16-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50248392
(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(F)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP1 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50247942
(CHEMBL521609 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP1 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248029
(CHEMBL516789 | N-(2,4-dichlorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(Cl)cc2Cl)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20Cl2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)26-13-11-21(29)16-23(26)30)28-24(32)7-4-8-25(28)36-22-12-9-18-5-2-3-6-19(18)15-22/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248027
(CHEMBL460321 | N-(2-chlorophenylsulfonyl)-3-(1-met...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccccc2Cl)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H21ClN2O4S/c1-31-18-21(14-16-27(32)30-36(33,34)26-12-5-4-9-23(26)29)28-24(31)10-6-11-25(28)35-22-15-13-19-7-2-3-8-20(19)17-22/h2-18H,1H3,(H,30,32)/b16-14+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serum |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50248583
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-18(26)17(25)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50247942
(CHEMBL521609 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from IP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50248168
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-17(21)26/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50248392
(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(F)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50247939
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)18(26)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50248333
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-16(26)15(25)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50248214
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-17(26)18(27)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-19(21)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50248278
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-17(28)16(27)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(25)9-15(20)26/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50247942
(CHEMBL521609 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50248168
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-17(21)26/h2-13H,1H3,(H,29,31)/b10-5+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP1 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50248583
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-18(26)17(25)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from IP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50247939
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)18(26)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin F2-alpha receptor
(Homo sapiens (Human)) | BDBM50248277
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from FP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50248277
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP1 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50248277
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50248278
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-17(28)16(27)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(25)9-15(20)26/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50248168
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-17(21)26/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50248392
(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(F)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50248392
(3-(4-(4-chloro-3-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(F)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostacyclin receptor
(Homo sapiens (Human)) | BDBM50248214
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-17(26)18(27)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-19(21)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from IP receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50248333
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-16(26)15(25)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50248333
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-16(26)15(25)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP1 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50248583
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-18(26)17(25)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50248214
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-17(26)18(27)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-19(21)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50248583
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-18(26)17(25)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50247939
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)18(26)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP1 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50248333
(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15ClF4N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-16(26)15(25)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50248214
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-17(26)18(27)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-19(21)28/h2-13H,1H3,(H,29,31)/b10-5+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP1 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50248214
(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3F)cccc12 Show InChI InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-17(26)18(27)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-19(21)28/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50248278
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-17(28)16(27)10-18(22)29)24-19(31)3-2-4-21(24)35-20-7-6-14(25)9-15(20)26/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50247942
(CHEMBL521609 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP2 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50247942
(CHEMBL521609 | N-(3,4-difluorophenylsulfonyl)-3-(1...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12 Show InChI InChI=1S/C28H20F2N2O4S/c1-32-17-20(10-14-27(33)31-37(34,35)22-12-13-23(29)24(30)16-22)28-25(32)7-4-8-26(28)36-21-11-9-18-5-2-3-6-19(18)15-21/h2-17H,1H3,(H,31,33)/b14-10+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50248277
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c1-31-12-13(5-8-23(32)30-36(33,34)22-11-18(28)17(27)10-19(22)29)24-20(31)3-2-4-21(24)35-14-6-7-15(25)16(26)9-14/h2-12H,1H3,(H,30,32)/b8-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50248168
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-17(21)26/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50247939
(3-(4-(3,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(Cl)c3)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-9-19(27)20(28)12-16)24-21(30)3-2-4-22(24)34-15-6-8-17(25)18(26)11-15/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Displacement of radioligand from EP4 receptor (unknown origin) |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50248168
(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)Show SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3Cl)cccc12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c1-30-13-14(5-10-23(31)29-35(32,33)16-7-8-18(27)19(28)12-16)24-20(30)3-2-4-22(24)34-21-9-6-15(25)11-17(21)26/h2-13H,1H3,(H,29,31)/b10-5+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 26.1 | n/a | n/a | n/a | n/a |
deCODE Chemistry
Curated by ChEMBL
| Assay Description Antagonist activity at human EP3-2 receptor expressed in CHOK1 cells |
Bioorg Med Chem Lett 19: 1528-31 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.112 BindingDB Entry DOI: 10.7270/Q2JM29H0 |
More data for this Ligand-Target Pair | |