Found 102 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248537
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248537
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248537
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248494
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50247946
(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1ccc(cc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-6-7-17(12-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay in presence of 8 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248538
(2-(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-5-7-17(8-6-16)26-14-20(24-25-26)18-3-1-2-4-19(18)23-13-15-9-11-22-12-10-15/h1-12,14,23H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247946
(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1ccc(cc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-6-7-17(12-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248584
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248491
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248075
(CHEMBL517021 | N-(quinolin-4-ylmethyl)-2-(1-(3-(tr...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C25H18F3N5/c26-25(27,28)18-6-5-7-19(14-18)33-16-24(31-32-33)21-9-2-4-11-23(21)30-15-17-12-13-29-22-10-3-1-8-20(17)22/h1-14,16,30H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248033
((1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(quin...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C24H18ClN5/c25-18-6-5-7-19(14-18)30-16-24(28-29-30)21-9-2-4-11-23(21)27-15-17-12-13-26-22-10-3-1-8-20(17)22/h1-14,16,27H,15H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247946
(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1ccc(cc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-6-7-17(12-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248033
((1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(quin...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C24H18ClN5/c25-18-6-5-7-19(14-18)30-16-24(28-29-30)21-9-2-4-11-23(21)27-15-17-12-13-26-22-10-3-1-8-20(17)22/h1-14,16,27H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248075
(CHEMBL517021 | N-(quinolin-4-ylmethyl)-2-(1-(3-(tr...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C25H18F3N5/c26-25(27,28)18-6-5-7-19(14-18)33-16-24(31-32-33)21-9-2-4-11-23(21)30-15-17-12-13-29-22-10-3-1-8-20(17)22/h1-14,16,30H,15H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248585
(2-(1-(3-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-7-6-8-20(15-19)29-17-23(27-28-29)21-9-4-5-10-22(21)26-16-18-11-13-25-14-12-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248585
(2-(1-(3-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-7-6-8-20(15-19)29-17-23(27-28-29)21-9-4-5-10-22(21)26-16-18-11-13-25-14-12-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248538
(2-(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-5-7-17(8-6-16)26-14-20(24-25-26)18-3-1-2-4-19(18)23-13-15-9-11-22-12-10-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248033
((1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(quin...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C24H18ClN5/c25-18-6-5-7-19(14-18)30-16-24(28-29-30)21-9-2-4-11-23(21)27-15-17-12-13-26-22-10-3-1-8-20(17)22/h1-14,16,27H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248075
(CHEMBL517021 | N-(quinolin-4-ylmethyl)-2-(1-(3-(tr...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccnc2ccccc12 Show InChI InChI=1S/C25H18F3N5/c26-25(27,28)18-6-5-7-19(14-18)33-16-24(31-32-33)21-9-2-4-11-23(21)30-15-17-12-13-29-22-10-3-1-8-20(17)22/h1-14,16,30H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248585
(2-(1-(3-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-7-6-8-20(15-19)29-17-23(27-28-29)21-9-4-5-10-22(21)26-16-18-11-13-25-14-12-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248538
(2-(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-5-7-17(8-6-16)26-14-20(24-25-26)18-3-1-2-4-19(18)23-13-15-9-11-22-12-10-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247943
(2-(1-(4-chloro-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES FC(F)(F)c1cc(ccc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H15ClF3N5/c22-18-6-5-15(11-17(18)21(23,24)25)30-13-20(28-29-30)16-3-1-2-4-19(16)27-12-14-7-9-26-10-8-14/h1-11,13,27H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50247943
(2-(1-(4-chloro-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES FC(F)(F)c1cc(ccc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H15ClF3N5/c22-18-6-5-15(11-17(18)21(23,24)25)30-13-20(28-29-30)16-3-1-2-4-19(16)27-12-14-7-9-26-10-8-14/h1-11,13,27H,12H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248586
(2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-8-10-20(11-9-19)29-17-23(27-28-29)21-6-4-5-7-22(21)26-16-18-12-14-25-15-13-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248539
(CHEMBL522304 | N-(pyridin-4-ylmethyl)-2-(1-(4-(tri...)Show SMILES FC(F)(F)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-5-7-17(8-6-16)29-14-20(27-28-29)18-3-1-2-4-19(18)26-13-15-9-11-25-12-10-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248586
(2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-8-10-20(11-9-19)29-17-23(27-28-29)21-6-4-5-7-22(21)26-16-18-12-14-25-15-13-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247945
(2-(1-(3,4-dichlorophenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES Clc1ccc(cc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C20H15Cl2N5/c21-17-6-5-15(11-18(17)22)27-13-20(25-26-27)16-3-1-2-4-19(16)24-12-14-7-9-23-10-8-14/h1-11,13,24H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248587
(CHEMBL461605 | N-(pyridin-4-ylmethyl)-2-(1-(quinol...)Show SMILES C(Nc1ccccc1-c1cn(nn1)-c1ccc2ccccc2n1)c1ccncc1 Show InChI InChI=1S/C23H18N6/c1-3-7-20-18(5-1)9-10-23(26-20)29-16-22(27-28-29)19-6-2-4-8-21(19)25-15-17-11-13-24-14-12-17/h1-14,16,25H,15H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248588
(2-(1-(1H-indazol-5-yl)-1H-1,2,3-triazol-4-yl)-N-(p...)Show SMILES C(Nc1ccccc1-c1cn(nn1)-c1ccc2[nH]ncc2c1)c1ccncc1 Show InChI InChI=1S/C21H17N7/c1-2-4-20(23-12-15-7-9-22-10-8-15)18(3-1)21-14-28(27-26-21)17-5-6-19-16(11-17)13-24-25-19/h1-11,13-14,23H,12H2,(H,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50247945
(2-(1-(3,4-dichlorophenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES Clc1ccc(cc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C20H15Cl2N5/c21-17-6-5-15(11-18(17)22)27-13-20(25-26-27)16-3-1-2-4-19(16)24-12-14-7-9-23-10-8-14/h1-11,13,24H,12H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248539
(CHEMBL522304 | N-(pyridin-4-ylmethyl)-2-(1-(4-(tri...)Show SMILES FC(F)(F)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-5-7-17(8-6-16)29-14-20(27-28-29)18-3-1-2-4-19(18)26-13-15-9-11-25-12-10-15/h1-12,14,26H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248588
(2-(1-(1H-indazol-5-yl)-1H-1,2,3-triazol-4-yl)-N-(p...)Show SMILES C(Nc1ccccc1-c1cn(nn1)-c1ccc2[nH]ncc2c1)c1ccncc1 Show InChI InChI=1S/C21H17N7/c1-2-4-20(23-12-15-7-9-22-10-8-15)18(3-1)21-14-28(27-26-21)17-5-6-19-16(11-17)13-24-25-19/h1-11,13-14,23H,12H2,(H,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248587
(CHEMBL461605 | N-(pyridin-4-ylmethyl)-2-(1-(quinol...)Show SMILES C(Nc1ccccc1-c1cn(nn1)-c1ccc2ccccc2n1)c1ccncc1 Show InChI InChI=1S/C23H18N6/c1-3-7-20-18(5-1)9-10-23(26-20)29-16-22(27-28-29)19-6-2-4-8-21(19)25-15-17-11-13-24-14-12-17/h1-14,16,25H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247943
(2-(1-(4-chloro-3-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES FC(F)(F)c1cc(ccc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H15ClF3N5/c22-18-6-5-15(11-17(18)21(23,24)25)30-13-20(28-29-30)16-3-1-2-4-19(16)27-12-14-7-9-26-10-8-14/h1-11,13,27H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50247967
(2-(1-(3-methyl-4-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1cc(ccc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-12-17(6-7-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247944
(2-(1-(3-chloro-4-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES FC(F)(F)c1ccc(cc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H15ClF3N5/c22-18-11-15(5-6-17(18)21(23,24)25)30-13-20(28-29-30)16-3-1-2-4-19(16)27-12-14-7-9-26-10-8-14/h1-11,13,27H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247967
(2-(1-(3-methyl-4-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1cc(ccc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-12-17(6-7-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248540
(CHEMBL491681 | N-(pyridin-4-ylmethyl)-2-(1-(4-(tri...)Show SMILES FC(F)(F)Oc1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-7-5-16(6-8-17)29-14-20(27-28-29)18-3-1-2-4-19(18)26-13-15-9-11-25-12-10-15/h1-12,14,26H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50247944
(2-(1-(3-chloro-4-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES FC(F)(F)c1ccc(cc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H15ClF3N5/c22-18-11-15(5-6-17(18)21(23,24)25)30-13-20(28-29-30)16-3-1-2-4-19(16)27-12-14-7-9-26-10-8-14/h1-11,13,27H,12H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248587
(CHEMBL461605 | N-(pyridin-4-ylmethyl)-2-(1-(quinol...)Show SMILES C(Nc1ccccc1-c1cn(nn1)-c1ccc2ccccc2n1)c1ccncc1 Show InChI InChI=1S/C23H18N6/c1-3-7-20-18(5-1)9-10-23(26-20)29-16-22(27-28-29)19-6-2-4-8-21(19)25-15-17-11-13-24-14-12-17/h1-14,16,25H,15H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248540
(CHEMBL491681 | N-(pyridin-4-ylmethyl)-2-(1-(4-(tri...)Show SMILES FC(F)(F)Oc1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-7-5-16(6-8-17)29-14-20(27-28-29)18-3-1-2-4-19(18)26-13-15-9-11-25-12-10-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247945
(2-(1-(3,4-dichlorophenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES Clc1ccc(cc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C20H15Cl2N5/c21-17-6-5-15(11-18(17)22)27-13-20(25-26-27)16-3-1-2-4-19(16)24-12-14-7-9-23-10-8-14/h1-11,13,24H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248586
(2-(1-(4-tert-butylphenyl)-1H-1,2,3-triazol-4-yl)-N...)Show SMILES CC(C)(C)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C24H25N5/c1-24(2,3)19-8-10-20(11-9-19)29-17-23(27-28-29)21-6-4-5-7-22(21)26-16-18-12-14-25-15-13-18/h4-15,17,26H,16H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248539
(CHEMBL522304 | N-(pyridin-4-ylmethyl)-2-(1-(4-(tri...)Show SMILES FC(F)(F)c1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-5-7-17(8-6-16)29-14-20(27-28-29)18-3-1-2-4-19(18)26-13-15-9-11-25-12-10-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247967
(2-(1-(3-methyl-4-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES Cc1cc(ccc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18F3N5/c1-15-12-17(6-7-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248588
(2-(1-(1H-indazol-5-yl)-1H-1,2,3-triazol-4-yl)-N-(p...)Show SMILES C(Nc1ccccc1-c1cn(nn1)-c1ccc2[nH]ncc2c1)c1ccncc1 Show InChI InChI=1S/C21H17N7/c1-2-4-20(23-12-15-7-9-22-10-8-15)18(3-1)21-14-28(27-26-21)17-5-6-19-16(11-17)13-24-25-19/h1-11,13-14,23H,12H2,(H,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50247944
(2-(1-(3-chloro-4-(trifluoromethyl)phenyl)-1H-1,2,3...)Show SMILES FC(F)(F)c1ccc(cc1Cl)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H15ClF3N5/c22-18-11-15(5-6-17(18)21(23,24)25)30-13-20(28-29-30)16-3-1-2-4-19(16)27-12-14-7-9-26-10-8-14/h1-11,13,27H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248540
(CHEMBL491681 | N-(pyridin-4-ylmethyl)-2-(1-(4-(tri...)Show SMILES FC(F)(F)Oc1ccc(cc1)-n1cc(nn1)-c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-7-5-16(6-8-17)29-14-20(27-28-29)18-3-1-2-4-19(18)26-13-15-9-11-25-12-10-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248492
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-6-3-7-17(11-16)26-14-20(24-25-26)18-8-1-2-9-19(18)23-13-15-5-4-10-22-12-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248077
(CHEMBL464620 | N-(3-Chlorophenyl)-5-(pyridin-4-ylm...)Show InChI InChI=1S/C15H13ClN6O/c16-11-2-1-3-12(8-11)19-15(23)13-14(21-22-20-13)18-9-10-4-6-17-7-5-10/h1-8H,9H2,(H,19,23)(H2,18,20,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248079
(5-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...)Show SMILES FC(F)(F)c1cccc(NC(=O)c2[nH]nnc2NCc2ccncc2)c1 Show InChI InChI=1S/C16H13F3N6O/c17-16(18,19)11-2-1-3-12(8-11)22-15(26)13-14(24-25-23-13)21-9-10-4-6-20-7-5-10/h1-8H,9H2,(H,22,26)(H2,21,23,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248078
(CHEMBL463032 | N-(4-chlorophenyl)-5-(pyridin-4-ylm...)Show InChI InChI=1S/C15H13ClN6O/c16-11-1-3-12(4-2-11)19-15(23)13-14(21-22-20-13)18-9-10-5-7-17-8-6-10/h1-8H,9H2,(H,19,23)(H2,18,20,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248076
(CHEMBL464619 | N-((1H-imidazol-4-yl)methyl)-2-(1-(...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1cnc[nH]1 Show InChI InChI=1S/C18H15ClN6/c19-13-4-3-5-15(8-13)25-11-18(23-24-25)16-6-1-2-7-17(16)21-10-14-9-20-12-22-14/h1-9,11-12,21H,10H2,(H,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248495
(CHEMBL490969 | N-(pyridin-3-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1cccnc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-6-3-7-17(11-16)29-14-20(27-28-29)18-8-1-2-9-19(18)26-13-15-5-4-10-25-12-15/h1-12,14,26H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248111
(5-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethyl)...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2[nH]nnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C16H13F3N6O/c17-16(18,19)11-1-3-12(4-2-11)22-15(26)13-14(24-25-23-13)21-9-10-5-7-20-8-6-10/h1-8H,9H2,(H,22,26)(H2,21,23,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248536
(CHEMBL523133 | N-(pyridin-2-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccccn1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)15-6-5-8-17(12-15)29-14-20(27-28-29)18-9-1-2-10-19(18)26-13-16-7-3-4-11-25-16/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248492
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-6-3-7-17(11-16)26-14-20(24-25-26)18-8-1-2-9-19(18)23-13-15-5-4-10-22-12-15/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248492
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-16-6-3-7-17(11-16)26-14-20(24-25-26)18-8-1-2-9-19(18)23-13-15-5-4-10-22-12-15/h1-12,14,23H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248030
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(3,...)Show SMILES Fc1ccc(CNc2ccccc2-c2cn(nn2)-c2cccc(Cl)c2)cc1F Show InChI InChI=1S/C21H15ClF2N4/c22-15-4-3-5-16(11-15)28-13-21(26-27-28)17-6-1-2-7-20(17)25-12-14-8-9-18(23)19(24)10-14/h1-11,13,25H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248495
(CHEMBL490969 | N-(pyridin-3-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1cccnc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-6-3-7-17(11-16)29-14-20(27-28-29)18-8-1-2-9-19(18)26-13-15-5-4-10-25-12-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248078
(CHEMBL463032 | N-(4-chlorophenyl)-5-(pyridin-4-ylm...)Show InChI InChI=1S/C15H13ClN6O/c16-11-1-3-12(4-2-11)19-15(23)13-14(21-22-20-13)18-9-10-5-7-17-8-6-10/h1-8H,9H2,(H,19,23)(H2,18,20,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248076
(CHEMBL464619 | N-((1H-imidazol-4-yl)methyl)-2-(1-(...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1cnc[nH]1 Show InChI InChI=1S/C18H15ClN6/c19-13-4-3-5-15(8-13)25-11-18(23-24-25)16-6-1-2-7-17(16)21-10-14-9-20-12-22-14/h1-9,11-12,21H,10H2,(H,20,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248032
(CHEMBL460959 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccc2OCOc2c1 Show InChI InChI=1S/C23H17F3N4O2/c24-23(25,26)16-4-3-5-17(11-16)30-13-20(28-29-30)18-6-1-2-7-19(18)27-12-15-8-9-21-22(10-15)32-14-31-21/h1-11,13,27H,12,14H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248030
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(3,...)Show SMILES Fc1ccc(CNc2ccccc2-c2cn(nn2)-c2cccc(Cl)c2)cc1F Show InChI InChI=1S/C21H15ClF2N4/c22-15-4-3-5-16(11-15)28-13-21(26-27-28)17-6-1-2-7-20(17)25-12-14-8-9-18(23)19(24)10-14/h1-11,13,25H,12H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248493
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-15-6-5-8-17(12-15)26-14-20(24-25-26)18-9-1-2-10-19(18)23-13-16-7-3-4-11-22-16/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248111
(5-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethyl)...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2[nH]nnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C16H13F3N6O/c17-16(18,19)11-1-3-12(4-2-11)22-15(26)13-14(24-25-23-13)21-9-10-5-7-20-8-6-10/h1-8H,9H2,(H,22,26)(H2,21,23,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248030
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(3,...)Show SMILES Fc1ccc(CNc2ccccc2-c2cn(nn2)-c2cccc(Cl)c2)cc1F Show InChI InChI=1S/C21H15ClF2N4/c22-15-4-3-5-16(11-15)28-13-21(26-27-28)17-6-1-2-7-20(17)25-12-14-8-9-18(23)19(24)10-14/h1-11,13,25H,12H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248536
(CHEMBL523133 | N-(pyridin-2-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccccn1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)15-6-5-8-17(12-15)29-14-20(27-28-29)18-9-1-2-10-19(18)26-13-16-7-3-4-11-25-16/h1-12,14,26H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248076
(CHEMBL464619 | N-((1H-imidazol-4-yl)methyl)-2-(1-(...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1cnc[nH]1 Show InChI InChI=1S/C18H15ClN6/c19-13-4-3-5-15(8-13)25-11-18(23-24-25)16-6-1-2-7-17(16)21-10-14-9-20-12-22-14/h1-9,11-12,21H,10H2,(H,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248032
(CHEMBL460959 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccc2OCOc2c1 Show InChI InChI=1S/C23H17F3N4O2/c24-23(25,26)16-4-3-5-17(11-16)30-13-20(28-29-30)18-6-1-2-7-19(18)27-12-15-8-9-21-22(10-15)32-14-31-21/h1-11,13,27H,12,14H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248031
(CHEMBL460958 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccc2OCOc2c1 Show InChI InChI=1S/C22H17ClN4O2/c23-16-4-3-5-17(11-16)27-13-20(25-26-27)18-6-1-2-7-19(18)24-12-15-8-9-21-22(10-15)29-14-28-21/h1-11,13,24H,12,14H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248031
(CHEMBL460958 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccc2OCOc2c1 Show InChI InChI=1S/C22H17ClN4O2/c23-16-4-3-5-17(11-16)27-13-20(25-26-27)18-6-1-2-7-19(18)24-12-15-8-9-21-22(10-15)29-14-28-21/h1-11,13,24H,12,14H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248031
(CHEMBL460958 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccc2OCOc2c1 Show InChI InChI=1S/C22H17ClN4O2/c23-16-4-3-5-17(11-16)27-13-20(25-26-27)18-6-1-2-7-19(18)24-12-15-8-9-21-22(10-15)29-14-28-21/h1-11,13,24H,12,14H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248536
(CHEMBL523133 | N-(pyridin-2-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccccn1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)15-6-5-8-17(12-15)29-14-20(27-28-29)18-9-1-2-10-19(18)26-13-16-7-3-4-11-25-16/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248495
(CHEMBL490969 | N-(pyridin-3-ylmethyl)-2-(1-(3-(tri...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1cccnc1 Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-6-3-7-17(11-16)29-14-20(27-28-29)18-8-1-2-9-19(18)26-13-15-5-4-10-25-12-15/h1-12,14,26H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248032
(CHEMBL460959 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccc2OCOc2c1 Show InChI InChI=1S/C23H17F3N4O2/c24-23(25,26)16-4-3-5-17(11-16)30-13-20(28-29-30)18-6-1-2-7-19(18)27-12-15-8-9-21-22(10-15)32-14-31-21/h1-11,13,27H,12,14H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50248493
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-15-6-5-8-17(12-15)26-14-20(24-25-26)18-9-1-2-10-19(18)23-13-16-7-3-4-11-22-16/h1-12,14,23H,13H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50248493
(2-(1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)Show InChI InChI=1S/C20H16ClN5/c21-15-6-5-8-17(12-15)26-14-20(24-25-26)18-9-1-2-10-19(18)23-13-16-7-3-4-11-22-16/h1-12,14,23H,13H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE
Curated by ChEMBL
| Assay Description Inhibition of VEGFR1 (unknown origin) by HTRF assay |
Bioorg Med Chem Lett 19: 1344-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.046 BindingDB Entry DOI: 10.7270/Q2DV1JRT |
More data for this Ligand-Target Pair | |