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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50035696 (1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 27.4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Biomedical Imaging and Bioengineering Curated by ChEMBL | Assay Description Antagonist activity at CXCR4 in human Jurkat cells assessed as inhibition of SDF1-induced cell migration | Bioorg Med Chem 17: 1486-93 (2009) Article DOI: 10.1016/j.bmc.2009.01.014 BindingDB Entry DOI: 10.7270/Q2930T1T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50035696 (1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Biomedical Imaging and Bioengineering Curated by ChEMBL | Assay Description Displacement of [125I]SDF1alpha from CXCR4 in human HL60 cells | Bioorg Med Chem 17: 1486-93 (2009) Article DOI: 10.1016/j.bmc.2009.01.014 BindingDB Entry DOI: 10.7270/Q2930T1T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
