Affinity Data by PubMed id=19254843

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50257522 (CHEMBL493342 \| CHO793076) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 1				Bioorg Med Chem Lett 19: 2018-21 (2009) Article DOI: 10.1016/j.bmcl.2009.02.031 BindingDB Entry DOI: 10.7270/Q2RV0NM0
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50092821 ((R)-4-Ethyl-4-methyl-1,4a,12,13a-tetrahydro-4H-2-o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 1				Bioorg Med Chem Lett 19: 2018-21 (2009) Article DOI: 10.1016/j.bmcl.2009.02.031 BindingDB Entry DOI: 10.7270/Q2RV0NM0
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%