Affinity Data by PubMed id=19286379

PubMed code 19286379

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50293280 (3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX2 in mouse peritoneal macrophages				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50293282 (CHEMBL504535 \| Imrecoxib) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX2 in mouse peritoneal macrophages				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50293280 (3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse peritoneal macrophages				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50293280 (3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of LPS-induced COX2 activity				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50293282 (CHEMBL504535 \| Imrecoxib) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse peritoneal macrophages				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50293281 (4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	409	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX2 in mouse peritoneal macrophages				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50293281 (4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse peritoneal macrophages				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50293281 (4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of calcimycin-induced COX1 activity				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%