Affinity Data by PubMed id=19305397

PubMed code 19305397

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36449 (CID25181262 \| ZINC12596968, 13) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36450 (CID25181263 \| ZINC09447957, 14) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36448 (CID8067740 \| ZINC06742509, 12) Show SMILES Fc1cccc(c1)C(=O)Nc1cccc(c1)-c1nn[n-]n1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36442 (CID7129233 \| ZINC04206703, 6) Show SMILES O=C1N(CCc2nn[n-]n2)C(=O)c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36441 (CID25181261 \| ZINC01707328, 5) Show SMILES [O-]C(=O)CN1C(=O)O[C@H](C1=O)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36446 (CID1714428 \| ZINC02028932, 10) Show SMILES [O-]S(=O)(=O)[C@H]1CC(=O)C(=O)c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	7.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36445 (CID7010321 \| ZINC02389418, 9) Show SMILES C(Oc1cccc(c1)-c1nn[n-]n1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36444 (CHEMBL61245 \| CID1550768 \| ZINC01669713, 8) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36447 (CID 7263523 \| ZINC04511491, 11) Show SMILES O=c1n(Cc2nn[n-]n2)cnc2sc3CCCCc3c12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36440 (CID25181259 \| ZINC13785333, 4) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM36447 (CID 7263523 \| ZINC04511491, 11) Show SMILES O=c1n(Cc2nn[n-]n2)cnc2sc3CCCCc3c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.50E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class C Beta-lactamase AmpC inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM36440 (CID25181259 \| ZINC13785333, 4) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class C Beta-lactamase AmpC inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM36448 (CID8067740 \| ZINC06742509, 12) Show SMILES Fc1cccc(c1)C(=O)Nc1cccc(c1)-c1nn[n-]n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.80E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class C Beta-lactamase AmpC inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36443 (CID7348363 \| ZINC04753704, 7) Show SMILES Nc1sc2CCCCc2c1-c1nn[n-]n1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM36437 (CID7357365 \| ZINC04784270, 1) Show SMILES CCc1c(C)[nH]n(-c2nn[n-]n2)c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class C Beta-lactamase AmpC inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM36439 (CID7100106 \| ZINC04105014, 3) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class C Beta-lactamase AmpC inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36439 (CID7100106 \| ZINC04105014, 3) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM36442 (CID7129233 \| ZINC04206703, 6) Show SMILES O=C1N(CCc2nn[n-]n2)C(=O)c2ccccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class C Beta-lactamase AmpC inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM36441 (CID25181261 \| ZINC01707328, 5) Show SMILES [O-]C(=O)CN1C(=O)O[C@H](C1=O)c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.50E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class C Beta-lactamase AmpC inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM36438 (CID25181258 \| ZINC04401406, 2) Show SMILES O=C1CCCC(Nc2nn[n-]n2)=C1 \|c:12\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.90E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class C Beta-lactamase AmpC inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36438 (CID25181258 \| ZINC04401406, 2) Show SMILES O=C1CCCC(Nc2nn[n-]n2)=C1 \|c:12\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	4.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair
Beta-lactamase CTX-M-1 (Escherichia coli)	BDBM36437 (CID7357365 \| ZINC04784270, 1) Show SMILES CCc1c(C)[nH]n(-c2nn[n-]n2)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
University of California, San Francisco					Assay Description Class A Beta-lactamase CTX-M inhibition assay				Nat Chem Biol 5: 358-64 (2009) Article DOI: 10.1038/nchembio.155 BindingDB Entry DOI: 10.7270/Q24M92WZ
University of California, San Francisco					More data for this Ligand-Target Pair

* indicates data uncertainty>20%