Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50257431 (1,25-dihydroxy-16-ene-20-cyclopropyl-vitamin D3 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a |
BioXell Curated by ChEMBL | Assay Description Activation of VDR in human THP1 cells assessed as increase in cathelicidin antimicrobial peptide mRNA expression by RT-PCR | J Med Chem 52: 2204-13 (2009) Article DOI: 10.1021/jm801365a BindingDB Entry DOI: 10.7270/Q2MS3SPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50293274 (1alpha,25(OH)2-24-oxo-16-ene-20-cyclopropyl-vitami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.690 | n/a | n/a | n/a | n/a |
BioXell Curated by ChEMBL | Assay Description Activation of VDR in human THP1 cells assessed as increase in 25-hydroxyvitamin D-24-hydroxylase mRNA expression by RT-PCR | J Med Chem 52: 2204-13 (2009) Article DOI: 10.1021/jm801365a BindingDB Entry DOI: 10.7270/Q2MS3SPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
BioXell Curated by ChEMBL | Assay Description Activation of VDR in human THP1 cells assessed as increase in 25-hydroxyvitamin D-24-hydroxylase mRNA expression by RT-PCR | J Med Chem 52: 2204-13 (2009) Article DOI: 10.1021/jm801365a BindingDB Entry DOI: 10.7270/Q2MS3SPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
BioXell Curated by ChEMBL | Assay Description Activation of VDR in human THP1 cells assessed as increase in cathelicidin antimicrobial peptide mRNA expression by RT-PCR | J Med Chem 52: 2204-13 (2009) Article DOI: 10.1021/jm801365a BindingDB Entry DOI: 10.7270/Q2MS3SPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50257431 (1,25-dihydroxy-16-ene-20-cyclopropyl-vitamin D3 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a |
BioXell Curated by ChEMBL | Assay Description Activation of VDR in human THP1 cells assessed as increase in 25-hydroxyvitamin D-24-hydroxylase mRNA expression by RT-PCR | J Med Chem 52: 2204-13 (2009) Article DOI: 10.1021/jm801365a BindingDB Entry DOI: 10.7270/Q2MS3SPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50293274 (1alpha,25(OH)2-24-oxo-16-ene-20-cyclopropyl-vitami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.690 | n/a | n/a | n/a | n/a |
BioXell Curated by ChEMBL | Assay Description Activation of VDR in human THP1 cells assessed as increase in cathelicidin antimicrobial peptide mRNA expression by RT-PCR | J Med Chem 52: 2204-13 (2009) Article DOI: 10.1021/jm801365a BindingDB Entry DOI: 10.7270/Q2MS3SPR | |||||||||||
More data for this Ligand-Target Pair |