Affinity Data by PubMed id=19328683

PubMed code 19328683

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50259047 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50259093 (1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.55E+3	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50259091 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50253704 (5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50253755 (5-(5-Chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50259048 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50259091 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50259049 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-N...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50259048 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.43E+3	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50259006 (1-(2,4-dichlorophenyl)-5-(5-iodothiophen-2-yl)-4-m...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.94E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50259006 (1-(2,4-dichlorophenyl)-5-(5-iodothiophen-2-yl)-4-m...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50259093 (1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50259049 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-N...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50253756 (CHEMBL461862 \| N-(Azepan-1-yl)-5-(5-chlorothiophen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50253756 (CHEMBL461862 \| N-(Azepan-1-yl)-5-(5-chlorothiophen...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50259092 (5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50253704 (5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.32E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50253755 (5-(5-Chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50259047 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50259092 (5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.12E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%