Found 7 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosinase
(Homo sapiens (Human)) | BDBM50031467
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Putra Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of tyrosinase |
Eur J Med Chem 44: 3195-200 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.020
BindingDB Entry DOI: 10.7270/Q29S1R35 |
More data for this
Ligand-Target Pair | |
Tyrosinase
(Homo sapiens (Human)) | BDBM50067044
((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)Show InChI InChI=1S/C17H14O3/c18-15-7-1-13(2-8-15)5-11-17(20)12-6-14-3-9-16(19)10-4-14/h1-12,18-19H/b11-5+,12-6+ | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Putra Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of tyrosinase |
Eur J Med Chem 44: 3195-200 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.020
BindingDB Entry DOI: 10.7270/Q29S1R35 |
More data for this
Ligand-Target Pair | |
Tyrosinase
(Homo sapiens (Human)) | BDBM50264832
(2,6-bis(4-hydroxybenzylidene)cyclohexanone | CHEMB...)Show InChI InChI=1S/C20H18O3/c21-18-8-4-14(5-9-18)12-16-2-1-3-17(20(16)23)13-15-6-10-19(22)11-7-15/h4-13,21-22H,1-3H2/b16-12+,17-13+ | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Putra Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of tyrosinase |
Eur J Med Chem 44: 3195-200 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.020
BindingDB Entry DOI: 10.7270/Q29S1R35 |
More data for this
Ligand-Target Pair | |
Tyrosinase
(Homo sapiens (Human)) | BDBM50296394
(1,5-bis(2-fluoro-4-methoxyphenyl)penta-1,4-dien-3-...)Show SMILES COc1ccc(\C=C\C(=O)\C=C\c2ccc(OC)cc2F)c(F)c1 Show InChI InChI=1S/C19H16F2O3/c1-23-16-9-5-13(18(20)11-16)3-7-15(22)8-4-14-6-10-17(24-2)12-19(14)21/h3-12H,1-2H3/b7-3+,8-4+ | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Putra Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of tyrosinase |
Eur J Med Chem 44: 3195-200 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.020
BindingDB Entry DOI: 10.7270/Q29S1R35 |
More data for this
Ligand-Target Pair | |
Tyrosinase
(Homo sapiens (Human)) | BDBM50067028
((1E,4E)-1,5-Bis-(4-hydroxy-3-methoxy-phenyl)-penta...)Show SMILES COc1cc(\C=C\C(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O Show InChI InChI=1S/C19H18O5/c1-23-18-11-13(5-9-16(18)21)3-7-15(20)8-4-14-6-10-17(22)19(12-14)24-2/h3-12,21-22H,1-2H3/b7-3+,8-4+ | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Putra Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of tyrosinase |
Eur J Med Chem 44: 3195-200 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.020
BindingDB Entry DOI: 10.7270/Q29S1R35 |
More data for this
Ligand-Target Pair | |
Tyrosinase
(Homo sapiens (Human)) | BDBM50266759
((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...)Show InChI InChI=1S/C17H12F2O/c18-15-7-1-13(2-8-15)5-11-17(20)12-6-14-3-9-16(19)10-4-14/h1-12H/b11-5+,12-6+ | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Putra Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of tyrosinase |
Eur J Med Chem 44: 3195-200 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.020
BindingDB Entry DOI: 10.7270/Q29S1R35 |
More data for this
Ligand-Target Pair | |
Tyrosinase
(Homo sapiens (Human)) | BDBM50296395
(2,6-Bis-(4-chloro-benzylidene)-cyclohexanone | 2,6...)Show SMILES Clc1ccc(\C=C2/CCC\C(=C/c3ccc(Cl)cc3)C2=O)cc1 Show InChI InChI=1S/C20H16Cl2O/c21-18-8-4-14(5-9-18)12-16-2-1-3-17(20(16)23)13-15-6-10-19(22)11-7-15/h4-13H,1-3H2/b16-12+,17-13+ | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Putra Malaysia
Curated by ChEMBL
| Assay Description
Inhibition of tyrosinase |
Eur J Med Chem 44: 3195-200 (2009)
Article DOI: 10.1016/j.ejmech.2009.03.020
BindingDB Entry DOI: 10.7270/Q29S1R35 |
More data for this
Ligand-Target Pair | |
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