Found 74 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293634
(CHEMBL569374 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C18H22BrN3O3/c19-15-11-14(5-6-21-18(23)17-12-20-13-25-17)3-4-16(15)24-10-9-22-7-1-2-8-22/h3-4,11-13H,1-2,5-10H2,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293636
(CHEMBL561293 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C18H22BrN3O2S/c19-15-13-14(5-6-20-17(23)18-21-7-12-25-18)3-4-16(15)24-11-10-22-8-1-2-9-22/h3-4,7,12-13H,1-2,5-6,8-11H2,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293623
(CHEMBL551841 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Brc1csc(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C19H22Br2N2O2S/c20-15-12-18(26-13-15)19(24)22-6-5-14-3-4-17(16(21)11-14)25-10-9-23-7-1-2-8-23/h3-4,11-13H,1-2,5-10H2,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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Similars
| Article
PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293637
(CHEMBL551488 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C18H22BrN3O2S/c19-15-11-14(5-6-21-18(23)17-12-20-13-25-17)3-4-16(15)24-10-9-22-7-1-2-8-22/h3-4,11-13H,1-2,5-10H2,(H,21,23) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293618
(CHEMBL563684 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C20H26BrN3O2/c1-23-10-4-5-18(23)20(25)22-9-8-16-6-7-19(17(21)15-16)26-14-13-24-11-2-3-12-24/h4-7,10,15H,2-3,8-9,11-14H2,1H3,(H,22,25) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293613
(CHEMBL554742 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C19H24BrN3O2/c20-16-14-15(7-9-22-19(24)17-4-3-8-21-17)5-6-18(16)25-13-12-23-10-1-2-11-23/h3-6,8,14,21H,1-2,7,9-13H2,(H,22,24) | PDB
Reactome pathway
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293628
(CHEMBL561228 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Brc1ccc(o1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C19H22Br2N2O3/c20-15-13-14(7-8-22-19(24)17-5-6-18(21)26-17)3-4-16(15)25-12-11-23-9-1-2-10-23/h3-6,13H,1-2,7-12H2,(H,22,24) | PDB
Reactome pathway
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293608
(CHEMBL561355 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Brc1c[nH]c(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C19H23Br2N3O2/c20-15-12-17(23-13-15)19(25)22-6-5-14-3-4-18(16(21)11-14)26-10-9-24-7-1-2-8-24/h3-4,11-13,23H,1-2,5-10H2,(H,22,25) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293639
(CHEMBL551693 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Brc1cccc(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C21H24Br2N2O2/c22-18-5-3-4-17(15-18)21(26)24-9-8-16-6-7-20(19(23)14-16)27-13-12-25-10-1-2-11-25/h3-7,14-15H,1-2,8-13H2,(H,24,26) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293638
(CHEMBL560629 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Clc1cccc(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C21H24BrClN2O2/c22-19-14-16(6-7-20(19)27-13-12-25-10-1-2-11-25)8-9-24-21(26)17-4-3-5-18(23)15-17/h3-7,14-15H,1-2,8-13H2,(H,24,26) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293633
(CHEMBL560230 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES FC(F)(F)c1cccc(n1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C21H23BrF3N3O2/c22-16-14-15(6-7-18(16)30-13-12-28-10-1-2-11-28)8-9-26-20(29)17-4-3-5-19(27-17)21(23,24)25/h3-7,14H,1-2,8-13H2,(H,26,29) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293631
(4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)e...)Show InChI InChI=1S/C20H24Br2N2O2S/c1-14-3-2-8-24(14)9-10-26-18-5-4-15(11-17(18)22)6-7-23-20(25)19-12-16(21)13-27-19/h4-5,11-14H,2-3,6-10H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293631
(4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)e...)Show InChI InChI=1S/C20H24Br2N2O2S/c1-14-3-2-8-24(14)9-10-26-18-5-4-15(11-17(18)22)6-7-23-20(25)19-12-16(21)13-27-19/h4-5,11-14H,2-3,6-10H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293635
(CHEMBL571006 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C17H22BrN5O2/c18-14-11-13(5-6-19-17(24)16-20-12-21-22-16)3-4-15(14)25-10-9-23-7-1-2-8-23/h3-4,11-12H,1-2,5-10H2,(H,19,24)(H,20,21,22) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293640
(CHEMBL563558 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C22H24BrF3N2O2/c23-19-14-16(6-7-20(19)30-13-12-28-10-1-2-11-28)8-9-27-21(29)17-4-3-5-18(15-17)22(24,25)26/h3-7,14-15H,1-2,8-13H2,(H,27,29) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293622
(CHEMBL559766 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C17H20Br2N2O2S/c1-21(2)7-8-23-15-4-3-12(9-14(15)19)5-6-20-17(22)16-10-13(18)11-24-16/h3-4,9-11H,5-8H2,1-2H3,(H,20,22) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| 670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50253285
(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)Show SMILES CN(C)CCCOc1ccc(CCNC(=O)c2cc(Br)c[nH]2)cc1Br Show InChI InChI=1S/C18H23Br2N3O2/c1-23(2)8-3-9-25-17-5-4-13(10-15(17)20)6-7-21-18(24)16-11-14(19)12-22-16/h4-5,10-12,22H,3,6-9H2,1-2H3,(H,21,24) | PDB
Reactome pathway
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PubMed
| 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293632
(4-bromo-N-(3-bromo-4-(2-(3-fluoropyrrolidin-1-yl)e...)Show SMILES FC1CCN(CCOc2ccc(CCNC(=O)c3cc(Br)cs3)cc2Br)C1 Show InChI InChI=1S/C19H21Br2FN2O2S/c20-14-10-18(27-12-14)19(25)23-5-3-13-1-2-17(16(21)9-13)26-8-7-24-6-4-15(22)11-24/h1-2,9-10,12,15H,3-8,11H2,(H,23,25) | PDB
Reactome pathway
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PubMed
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293632
(4-bromo-N-(3-bromo-4-(2-(3-fluoropyrrolidin-1-yl)e...)Show SMILES FC1CCN(CCOc2ccc(CCNC(=O)c3cc(Br)cs3)cc2Br)C1 Show InChI InChI=1S/C19H21Br2FN2O2S/c20-14-10-18(27-12-14)19(25)23-5-3-13-1-2-17(16(21)9-13)26-8-7-24-6-4-15(22)11-24/h1-2,9-10,12,15H,3-8,11H2,(H,23,25) | PDB
Reactome pathway
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Similars
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PubMed
| 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293625
(CHEMBL559963 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show SMILES CN1CCCC(COc2ccc(CCNC(=O)c3cc(Br)cs3)cc2Br)C1 Show InChI InChI=1S/C20H24Br2N2O2S/c1-24-8-2-3-15(11-24)12-26-18-5-4-14(9-17(18)22)6-7-23-20(25)19-10-16(21)13-27-19/h4-5,9-10,13,15H,2-3,6-8,11-12H2,1H3,(H,23,25) | PDB
Reactome pathway
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293610
(CHEMBL554516 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show SMILES CN1CCCC(COc2ccc(CCNC(=O)c3cc(Br)c[nH]3)cc2Br)C1 Show InChI InChI=1S/C20H25Br2N3O2/c1-25-8-2-3-15(12-25)13-27-19-5-4-14(9-17(19)22)6-7-23-20(26)18-10-16(21)11-24-18/h4-5,9-11,15,24H,2-3,6-8,12-13H2,1H3,(H,23,26) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Patents
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| Article
PubMed
| 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293611
(CHEMBL561234 | N-(3-bromo-4-(3-(dimethylamino)prop...)Show InChI InChI=1S/C18H24BrN3O2/c1-22(2)11-4-12-24-17-7-6-14(13-15(17)19)8-10-21-18(23)16-5-3-9-20-16/h3,5-7,9,13,20H,4,8,10-12H2,1-2H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC sid
UniChem
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PubMed
| 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293615
(CHEMBL564035 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show SMILES CN1CCCC(COc2ccc(CCNC(=O)c3ccc[nH]3)cc2Br)C1 Show InChI InChI=1S/C20H26BrN3O2/c1-24-11-3-4-16(13-24)14-26-19-7-6-15(12-17(19)21)8-10-23-20(25)18-5-2-9-22-18/h2,5-7,9,12,16,22H,3-4,8,10-11,13-14H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293612
(CHEMBL561433 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C17H22BrN3O2/c1-21(2)10-11-23-16-6-5-13(12-14(16)18)7-9-20-17(22)15-4-3-8-19-15/h3-6,8,12,19H,7,9-11H2,1-2H3,(H,20,22) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| 1.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293607
(CHEMBL570774 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C17H21Br2N3O2/c1-22(2)7-8-24-16-4-3-12(9-14(16)19)5-6-20-17(23)15-10-13(18)11-21-15/h3-4,9-11,21H,5-8H2,1-2H3,(H,20,23) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293621
(CHEMBL551840 | N-(3-bromo-4-(3-(dimethylamino)prop...)Show InChI InChI=1S/C18H22Br2N2O2S/c1-22(2)8-3-9-24-16-5-4-13(10-15(16)20)6-7-21-18(23)17-11-14(19)12-25-17/h4-5,10-12H,3,6-9H2,1-2H3,(H,21,23) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293620
(CHEMBL562235 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show InChI InChI=1S/C21H28BrN3O2/c1-24-11-3-5-17(14-24)15-27-20-8-7-16(13-18(20)22)9-10-23-21(26)19-6-4-12-25(19)2/h4,6-8,12-13,17H,3,5,9-11,14-15H2,1-2H3,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC sid
UniChem
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PubMed
| 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293616
(CHEMBL561837 | N-(3-bromo-4-(3-(dimethylamino)prop...)Show InChI InChI=1S/C19H26BrN3O2/c1-22(2)11-5-13-25-18-8-7-15(14-16(18)20)9-10-21-19(24)17-6-4-12-23(17)3/h4,6-8,12,14H,5,9-11,13H2,1-3H3,(H,21,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC sid
UniChem
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PubMed
| 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293630
(CHEMBL559842 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show SMILES CN1CCCC(COc2ccc(CCNC(=O)c3ccc(Br)o3)cc2Br)C1 Show InChI InChI=1S/C20H24Br2N2O3/c1-24-10-2-3-15(12-24)13-26-17-5-4-14(11-16(17)21)8-9-23-20(25)18-6-7-19(22)27-18/h4-7,11,15H,2-3,8-10,12-13H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC sid
UniChem
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PubMed
| 2.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293617
(CHEMBL550141 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C18H24BrN3O2/c1-21(2)11-12-24-17-7-6-14(13-15(17)19)8-9-20-18(23)16-5-4-10-22(16)3/h4-7,10,13H,8-9,11-12H2,1-3H3,(H,20,23) | PDB
Reactome pathway
KEGG
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| 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293626
(CHEMBL554108 | N-(3-bromo-4-(3-(dimethylamino)prop...)Show InChI InChI=1S/C18H22Br2N2O3/c1-22(2)10-3-11-24-15-5-4-13(12-14(15)19)8-9-21-18(23)16-6-7-17(20)25-16/h4-7,12H,3,8-11H2,1-2H3,(H,21,23) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293627
(CHEMBL562297 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C17H20Br2N2O3/c1-21(2)9-10-23-14-4-3-12(11-13(14)18)7-8-20-17(22)15-5-6-16(19)24-15/h3-6,11H,7-10H2,1-2H3,(H,20,22) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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PubMed
| 2.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293609
(CHEMBL549332 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show SMILES Brc1c[nH]c(c1)C(=O)NCCc1ccc(OCCN2CCOCC2)c(Br)c1 Show InChI InChI=1S/C19H23Br2N3O3/c20-15-12-17(23-13-15)19(25)22-4-3-14-1-2-18(16(21)11-14)27-10-7-24-5-8-26-9-6-24/h1-2,11-13,23H,3-10H2,(H,22,25) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
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PubMed
| 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293624
(CHEMBL549544 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show SMILES Brc1csc(c1)C(=O)NCCc1ccc(OCCN2CCOCC2)c(Br)c1 Show InChI InChI=1S/C19H22Br2N2O3S/c20-15-12-18(27-13-15)19(24)22-4-3-14-1-2-17(16(21)11-14)26-10-7-23-5-8-25-9-6-23/h1-2,11-13H,3-10H2,(H,22,24) | PDB
Reactome pathway
KEGG
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UniChem
Similars
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PubMed
| 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293619
(CHEMBL561029 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show InChI InChI=1S/C20H26BrN3O3/c1-23-8-2-3-18(23)20(25)22-7-6-16-4-5-19(17(21)15-16)27-14-11-24-9-12-26-13-10-24/h2-5,8,15H,6-7,9-14H2,1H3,(H,22,25) | PDB
Reactome pathway
KEGG
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UniChem
Similars
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PubMed
| 1.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293614
(CHEMBL563666 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show InChI InChI=1S/C19H24BrN3O3/c20-16-14-15(5-7-22-19(24)17-2-1-6-21-17)3-4-18(16)26-13-10-23-8-11-25-12-9-23/h1-4,6,14,21H,5,7-13H2,(H,22,24) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
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PubMed
| 2.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293629
(CHEMBL559448 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show SMILES Brc1ccc(o1)C(=O)NCCc1ccc(OCCN2CCOCC2)c(Br)c1 Show InChI InChI=1S/C19H22Br2N2O4/c20-15-13-14(5-6-22-19(24)17-3-4-18(21)27-17)1-2-16(15)26-12-9-23-7-10-25-11-8-23/h1-4,13H,5-12H2,(H,22,24) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
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PubMed
| 3.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293636
(CHEMBL561293 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C18H22BrN3O2S/c19-15-13-14(5-6-20-17(23)18-21-7-12-25-18)3-4-16(15)24-11-10-22-8-1-2-9-22/h3-4,7,12-13H,1-2,5-6,8-11H2,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293634
(CHEMBL569374 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C18H22BrN3O3/c19-15-11-14(5-6-21-18(23)17-12-20-13-25-17)3-4-16(15)24-10-9-22-7-1-2-8-22/h3-4,11-13H,1-2,5-10H2,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293623
(CHEMBL551841 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Brc1csc(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C19H22Br2N2O2S/c20-15-12-18(26-13-15)19(24)22-6-5-14-3-4-17(16(21)11-14)25-10-9-23-7-1-2-8-23/h3-4,11-13H,1-2,5-10H2,(H,22,24) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293637
(CHEMBL551488 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C18H22BrN3O2S/c19-15-11-14(5-6-21-18(23)17-12-20-13-25-17)3-4-16(15)24-10-9-22-7-1-2-8-22/h3-4,11-13H,1-2,5-10H2,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293618
(CHEMBL563684 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C20H26BrN3O2/c1-23-10-4-5-18(23)20(25)22-9-8-16-6-7-19(17(21)15-16)26-14-13-24-11-2-3-12-24/h4-7,10,15H,2-3,8-9,11-14H2,1H3,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293613
(CHEMBL554742 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C19H24BrN3O2/c20-16-14-15(7-9-22-19(24)17-4-3-8-21-17)5-6-18(16)25-13-12-23-10-1-2-11-23/h3-6,8,14,21H,1-2,7,9-13H2,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293628
(CHEMBL561228 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Brc1ccc(o1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C19H22Br2N2O3/c20-15-13-14(7-8-22-19(24)17-5-6-18(21)26-17)3-4-16(15)25-12-11-23-9-1-2-10-23/h3-6,13H,1-2,7-12H2,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293608
(CHEMBL561355 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Brc1c[nH]c(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C19H23Br2N3O2/c20-15-12-17(23-13-15)19(25)22-6-5-14-3-4-18(16(21)11-14)26-10-9-24-7-1-2-8-24/h3-4,11-13,23H,1-2,5-10H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293639
(CHEMBL551693 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Brc1cccc(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C21H24Br2N2O2/c22-18-5-3-4-17(15-18)21(26)24-9-8-16-6-7-20(19(23)14-16)27-13-12-25-10-1-2-11-25/h3-7,14-15H,1-2,8-13H2,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293638
(CHEMBL560629 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES Clc1cccc(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C21H24BrClN2O2/c22-19-14-16(6-7-20(19)27-13-12-25-10-1-2-11-25)8-9-24-21(26)17-4-3-5-18(23)15-17/h3-7,14-15H,1-2,8-13H2,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293633
(CHEMBL560230 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES FC(F)(F)c1cccc(n1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C21H23BrF3N3O2/c22-16-14-15(6-7-18(16)30-13-12-28-10-1-2-11-28)8-9-26-20(29)17-4-3-5-19(27-17)21(23,24)25/h3-7,14H,1-2,8-13H2,(H,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293631
(4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)e...)Show InChI InChI=1S/C20H24Br2N2O2S/c1-14-3-2-8-24(14)9-10-26-18-5-4-15(11-17(18)22)6-7-23-20(25)19-12-16(21)13-27-19/h4-5,11-14H,2-3,6-10H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293631
(4-bromo-N-(3-bromo-4-(2-(2-methylpyrrolidin-1-yl)e...)Show InChI InChI=1S/C20H24Br2N2O2S/c1-14-3-2-8-24(14)9-10-26-18-5-4-15(11-17(18)22)6-7-23-20(25)19-12-16(21)13-27-19/h4-5,11-14H,2-3,6-10H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293635
(CHEMBL571006 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show InChI InChI=1S/C17H22BrN5O2/c18-14-11-13(5-6-19-17(24)16-20-12-21-22-16)3-4-15(14)25-10-9-23-7-1-2-8-23/h3-4,11-12H,1-2,5-10H2,(H,19,24)(H,20,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293640
(CHEMBL563558 | N-(3-bromo-4-(2-(pyrrolidin-1-yl)et...)Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCCc1ccc(OCCN2CCCC2)c(Br)c1 Show InChI InChI=1S/C22H24BrF3N2O2/c23-19-14-16(6-7-20(19)30-13-12-28-10-1-2-11-28)8-9-27-21(29)17-4-3-5-18(15-17)22(24,25)26/h3-7,14-15H,1-2,8-13H2,(H,27,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293622
(CHEMBL559766 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C17H20Br2N2O2S/c1-21(2)7-8-23-15-4-3-12(9-14(15)19)5-6-20-17(22)16-10-13(18)11-24-16/h3-4,9-11H,5-8H2,1-2H3,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293632
(4-bromo-N-(3-bromo-4-(2-(3-fluoropyrrolidin-1-yl)e...)Show SMILES FC1CCN(CCOc2ccc(CCNC(=O)c3cc(Br)cs3)cc2Br)C1 Show InChI InChI=1S/C19H21Br2FN2O2S/c20-14-10-18(27-12-14)19(25)23-5-3-13-1-2-17(16(21)9-13)26-8-7-24-6-4-15(22)11-24/h1-2,9-10,12,15H,3-8,11H2,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293632
(4-bromo-N-(3-bromo-4-(2-(3-fluoropyrrolidin-1-yl)e...)Show SMILES FC1CCN(CCOc2ccc(CCNC(=O)c3cc(Br)cs3)cc2Br)C1 Show InChI InChI=1S/C19H21Br2FN2O2S/c20-14-10-18(27-12-14)19(25)23-5-3-13-1-2-17(16(21)9-13)26-8-7-24-6-4-15(22)11-24/h1-2,9-10,12,15H,3-8,11H2,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50253285
(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)Show SMILES CN(C)CCCOc1ccc(CCNC(=O)c2cc(Br)c[nH]2)cc1Br Show InChI InChI=1S/C18H23Br2N3O2/c1-23(2)8-3-9-25-17-5-4-13(10-15(17)20)6-7-21-18(24)16-11-14(19)12-22-16/h4-5,10-12,22H,3,6-9H2,1-2H3,(H,21,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293611
(CHEMBL561234 | N-(3-bromo-4-(3-(dimethylamino)prop...)Show InChI InChI=1S/C18H24BrN3O2/c1-22(2)11-4-12-24-17-7-6-14(13-15(17)19)8-10-21-18(23)16-5-3-9-20-16/h3,5-7,9,13,20H,4,8,10-12H2,1-2H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293610
(CHEMBL554516 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show SMILES CN1CCCC(COc2ccc(CCNC(=O)c3cc(Br)c[nH]3)cc2Br)C1 Show InChI InChI=1S/C20H25Br2N3O2/c1-25-8-2-3-15(12-25)13-27-19-5-4-14(9-17(19)22)6-7-23-20(26)18-10-16(21)11-24-18/h4-5,9-11,15,24H,2-3,6-8,12-13H2,1H3,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293612
(CHEMBL561433 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C17H22BrN3O2/c1-21(2)10-11-23-16-6-5-13(12-14(16)18)7-9-20-17(22)15-4-3-8-19-15/h3-6,8,12,19H,7,9-11H2,1-2H3,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293621
(CHEMBL551840 | N-(3-bromo-4-(3-(dimethylamino)prop...)Show InChI InChI=1S/C18H22Br2N2O2S/c1-22(2)8-3-9-24-16-5-4-13(10-15(16)20)6-7-21-18(23)17-11-14(19)12-25-17/h4-5,10-12H,3,6-9H2,1-2H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293620
(CHEMBL562235 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show InChI InChI=1S/C21H28BrN3O2/c1-24-11-3-5-17(14-24)15-27-20-8-7-16(13-18(20)22)9-10-23-21(26)19-6-4-12-25(19)2/h4,6-8,12-13,17H,3,5,9-11,14-15H2,1-2H3,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293615
(CHEMBL564035 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show SMILES CN1CCCC(COc2ccc(CCNC(=O)c3ccc[nH]3)cc2Br)C1 Show InChI InChI=1S/C20H26BrN3O2/c1-24-11-3-4-16(13-24)14-26-19-7-6-15(12-17(19)21)8-10-23-20(25)18-5-2-9-22-18/h2,5-7,9,12,16,22H,3-4,8,10-11,13-14H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293607
(CHEMBL570774 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C17H21Br2N3O2/c1-22(2)7-8-24-16-4-3-12(9-14(16)19)5-6-20-17(23)15-10-13(18)11-21-15/h3-4,9-11,21H,5-8H2,1-2H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293625
(CHEMBL559963 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show SMILES CN1CCCC(COc2ccc(CCNC(=O)c3cc(Br)cs3)cc2Br)C1 Show InChI InChI=1S/C20H24Br2N2O2S/c1-24-8-2-3-15(11-24)12-26-18-5-4-14(9-17(18)22)6-7-23-20(25)19-10-16(21)13-27-19/h4-5,9-10,13,15H,2-3,6-8,11-12H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293616
(CHEMBL561837 | N-(3-bromo-4-(3-(dimethylamino)prop...)Show InChI InChI=1S/C19H26BrN3O2/c1-22(2)11-5-13-25-18-8-7-15(14-16(18)20)9-10-21-19(24)17-6-4-12-23(17)3/h4,6-8,12,14H,5,9-11,13H2,1-3H3,(H,21,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293617
(CHEMBL550141 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C18H24BrN3O2/c1-21(2)11-12-24-17-7-6-14(13-15(17)19)8-9-20-18(23)16-5-4-10-22(16)3/h4-7,10,13H,8-9,11-12H2,1-3H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293630
(CHEMBL559842 | N-(3-bromo-4-((1-methylpiperidin-3-...)Show SMILES CN1CCCC(COc2ccc(CCNC(=O)c3ccc(Br)o3)cc2Br)C1 Show InChI InChI=1S/C20H24Br2N2O3/c1-24-10-2-3-15(12-24)13-26-17-5-4-14(11-16(17)21)8-9-23-20(25)18-6-7-19(22)27-18/h4-7,11,15H,2-3,8-10,12-13H2,1H3,(H,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293626
(CHEMBL554108 | N-(3-bromo-4-(3-(dimethylamino)prop...)Show InChI InChI=1S/C18H22Br2N2O3/c1-22(2)10-3-11-24-15-5-4-13(12-14(15)19)8-9-21-18(23)16-6-7-17(20)25-16/h4-7,12H,3,8-11H2,1-2H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293627
(CHEMBL562297 | N-(3-bromo-4-(2-(dimethylamino)etho...)Show InChI InChI=1S/C17H20Br2N2O3/c1-21(2)9-10-23-14-4-3-12(11-13(14)18)7-8-20-17(22)15-5-6-16(19)24-15/h3-6,11H,7-10H2,1-2H3,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293609
(CHEMBL549332 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show SMILES Brc1c[nH]c(c1)C(=O)NCCc1ccc(OCCN2CCOCC2)c(Br)c1 Show InChI InChI=1S/C19H23Br2N3O3/c20-15-12-17(23-13-15)19(25)22-4-3-14-1-2-18(16(21)11-14)27-10-7-24-5-8-26-9-6-24/h1-2,11-13,23H,3-10H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293624
(CHEMBL549544 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show SMILES Brc1csc(c1)C(=O)NCCc1ccc(OCCN2CCOCC2)c(Br)c1 Show InChI InChI=1S/C19H22Br2N2O3S/c20-15-12-18(27-13-15)19(24)22-4-3-14-1-2-17(16(21)11-14)26-10-7-23-5-8-25-9-6-23/h1-2,11-13H,3-10H2,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293619
(CHEMBL561029 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show InChI InChI=1S/C20H26BrN3O3/c1-23-8-2-3-18(23)20(25)22-7-6-16-4-5-19(17(21)15-16)27-14-11-24-9-12-26-13-10-24/h2-5,8,15H,6-7,9-14H2,1H3,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293614
(CHEMBL563666 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show InChI InChI=1S/C19H24BrN3O3/c20-16-14-15(5-7-22-19(24)17-2-1-6-21-17)3-4-18(16)26-13-10-23-8-11-25-12-9-23/h1-4,6,14,21H,5,7-13H2,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50293629
(CHEMBL559448 | N-(3-bromo-4-(2-morpholinoethoxy)ph...)Show SMILES Brc1ccc(o1)C(=O)NCCc1ccc(OCCN2CCOCC2)c(Br)c1 Show InChI InChI=1S/C19H22Br2N2O4/c20-15-13-14(5-6-22-19(24)17-3-4-18(21)27-17)1-2-16(15)26-12-9-23-7-10-25-11-8-23/h1-4,13H,5-12H2,(H,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description
Displacement of [3H]SMT from human histamine H3 receptor |
Bioorg Med Chem Lett 19: 3204-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.106
BindingDB Entry DOI: 10.7270/Q2NS0TXG |
More data for this
Ligand-Target Pair | |
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