Found 52 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM23971
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298264
(4-Bromo-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-1...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Br)c(c1)[N+]([O-])=O)C(=O)NO)=N[N+]([O-])=O |r,w:24.25| Show InChI InChI=1S/C13H16BrN7O7/c14-8-4-3-7(6-10(8)20(25)26)11(22)17-9(12(23)19-24)2-1-5-16-13(15)18-21(27)28/h3-4,6,9,24H,1-2,5H2,(H,17,22)(H,19,23)(H3,15,16,18)/t9-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298262
(2,4-Dichloro-N-(1-(hydroxyamino)-5-(3-nitroguanidi...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Cl)cc1Cl)C(=O)NO)=N[N+]([O-])=O |r,w:22.23| Show InChI InChI=1S/C13H16Cl2N6O5/c14-7-3-4-8(9(15)6-7)11(22)18-10(12(23)20-24)2-1-5-17-13(16)19-21(25)26/h3-4,6,10,24H,1-2,5H2,(H,18,22)(H,20,23)(H3,16,17,19)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298246
(CHEMBL584358 | N-Hydroxy-5-(3-nitroguanidino)-2-(2...)Show SMILES NC(NCCC[C@H](NC(=O)Cc1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C14H20N6O5/c15-14(18-20(24)25)16-8-4-7-11(13(22)19-23)17-12(21)9-10-5-2-1-3-6-10/h1-3,5-6,11,23H,4,7-9H2,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298265
(CHEMBL582839 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)NO)=N[N+]([O-])=O |r,w:24.26| Show InChI InChI=1S/C17H20N6O5/c18-17(21-23(27)28)19-9-3-6-14(16(25)22-26)20-15(24)13-8-7-11-4-1-2-5-12(11)10-13/h1-2,4-5,7-8,10,14,26H,3,6,9H2,(H,20,24)(H,22,25)(H3,18,19,21)/t14-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298260
(CHEMBL575800 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NO)=N[N+]([O-])=O |r,w:23.24| Show InChI InChI=1S/C13H17N7O7/c14-13(17-20(26)27)15-7-1-2-10(12(22)18-23)16-11(21)8-3-5-9(6-4-8)19(24)25/h3-6,10,23H,1-2,7H2,(H,16,21)(H,18,22)(H3,14,15,17)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298257
(CHEMBL576974 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1cccc(c1)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:18.19| Show InChI InChI=1S/C14H20N6O6/c1-26-10-5-2-4-9(8-10)12(21)17-11(13(22)19-23)6-3-7-16-14(15)18-20(24)25/h2,4-5,8,11,23H,3,6-7H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298250
(2-Chloro-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccccc1Cl)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17ClN6O5/c14-9-5-2-1-4-8(9)11(21)17-10(12(22)19-23)6-3-7-16-13(15)18-20(24)25/h1-2,4-5,10,23H,3,6-7H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298251
(CHEMBL574757 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccccc1I)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17IN6O5/c14-9-5-2-1-4-8(9)11(21)17-10(12(22)19-23)6-3-7-16-13(15)18-20(24)25/h1-2,4-5,10,23H,3,6-7H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298266
(CHEMBL574273 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1ccc(cc1OC)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:20.21| Show InChI InChI=1S/C15H22N6O7/c1-27-11-6-5-9(8-12(11)28-2)13(22)18-10(14(23)20-24)4-3-7-17-15(16)19-21(25)26/h5-6,8,10,24H,3-4,7H2,1-2H3,(H,18,22)(H,20,23)(H3,16,17,19)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298270
(CHEMBL575400 | N-Hydroxy-2-(4-methylphenylsulfonam...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:18.19| Show InChI InChI=1S/C13H20N6O6S/c1-9-4-6-10(7-5-9)26(24,25)18-11(12(20)17-21)3-2-8-15-13(14)16-19(22)23/h4-7,11,18,21H,2-3,8H2,1H3,(H,17,20)(H3,14,15,16)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298263
(3,4-Dichloro-N-(1-(hydroxyamino)-5-(3-nitroguanidi...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)NO)=N[N+]([O-])=O |r,w:22.23| Show InChI InChI=1S/C13H16Cl2N6O5/c14-8-4-3-7(6-9(8)15)11(22)18-10(12(23)20-24)2-1-5-17-13(16)19-21(25)26/h3-4,6,10,24H,1-2,5H2,(H,18,22)(H,20,23)(H3,16,17,19)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298248
(2-Cinnamamido-N-hydroxy-5-(3-nitroguanidino)pentan...)Show SMILES NC(NCCC[C@H](NC(=O)C=Cc1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:22.23,10.9| Show InChI InChI=1S/C15H20N6O5/c16-15(19-21(25)26)17-10-4-7-12(14(23)20-24)18-13(22)9-8-11-5-2-1-3-6-11/h1-3,5-6,8-9,12,24H,4,7,10H2,(H,18,22)(H,20,23)(H3,16,17,19)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298267
(CHEMBL574274 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:22.23| Show InChI InChI=1S/C16H24N6O8/c1-28-11-7-9(8-12(29-2)13(11)30-3)14(23)19-10(15(24)21-25)5-4-6-18-16(17)20-22(26)27/h7-8,10,25H,4-6H2,1-3H3,(H,19,23)(H,21,24)(H3,17,18,20)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298256
(CHEMBL573304 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES Cc1cccc(c1)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:17.18| Show InChI InChI=1S/C14H20N6O5/c1-9-4-2-5-10(8-9)12(21)17-11(13(22)19-23)6-3-7-16-14(15)18-20(24)25/h2,4-5,8,11,23H,3,6-7H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298255
(CHEMBL584601 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1cccc(c1)[N+]([O-])=O)C(=O)NO)=N[N+]([O-])=O |r,w:23.24| Show InChI InChI=1S/C13H17N7O7/c14-13(17-20(26)27)15-6-2-5-10(12(22)18-23)16-11(21)8-3-1-4-9(7-8)19(24)25/h1,3-4,7,10,23H,2,5-6H2,(H,16,21)(H,18,22)(H3,14,15,17)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298261
(CHEMBL574056 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1ccc(cc1)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:18.19| Show InChI InChI=1S/C14H20N6O6/c1-26-10-6-4-9(5-7-10)12(21)17-11(13(22)19-23)3-2-8-16-14(15)18-20(24)25/h4-7,11,23H,2-3,8H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298269
(CHEMBL575397 | N-Hydroxy-5-(3-nitroguanidino)-2-(p...)Show SMILES NC(NCCC[C@H](NS(=O)(=O)c1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C12H18N6O6S/c13-12(15-18(21)22)14-8-4-7-10(11(19)16-20)17-25(23,24)9-5-2-1-3-6-9/h1-3,5-6,10,17,20H,4,7-8H2,(H,16,19)(H3,13,14,15)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298253
(CHEMBL576973 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1ccccc1C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:18.19| Show InChI InChI=1S/C14H20N6O6/c1-26-11-7-3-2-5-9(11)12(21)17-10(13(22)19-23)6-4-8-16-14(15)18-20(24)25/h2-3,5,7,10,23H,4,6,8H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298249
(CHEMBL583058 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:20.21| Show InChI InChI=1S/C13H18N6O5/c14-13(17-19(23)24)15-8-4-7-10(12(21)18-22)16-11(20)9-5-2-1-3-6-9/h1-3,5-6,10,22H,4,7-8H2,(H,16,20)(H,18,21)(H3,14,15,17)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298265
(CHEMBL582839 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)NO)=N[N+]([O-])=O |r,w:24.26| Show InChI InChI=1S/C17H20N6O5/c18-17(21-23(27)28)19-9-3-6-14(16(25)22-26)20-15(24)13-8-7-11-4-1-2-5-12(11)10-13/h1-2,4-5,7-8,10,14,26H,3,6,9H2,(H,20,24)(H,22,25)(H3,18,19,21)/t14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298268
(CHEMBL583183 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1cccs1)C(=O)NO)=N[N+]([O-])=O |r,w:19.20| Show InChI InChI=1S/C11H16N6O5S/c12-11(15-17(21)22)13-5-1-3-7(9(18)16-20)14-10(19)8-4-2-6-23-8/h2,4,6-7,20H,1,3,5H2,(H,14,19)(H,16,18)(H3,12,13,15)/t7-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298254
(3-Chloro-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-...)Show SMILES NC(NCCC[C@H](NC(=O)c1cccc(Cl)c1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17ClN6O5/c14-9-4-1-3-8(7-9)11(21)17-10(12(22)19-23)5-2-6-16-13(15)18-20(24)25/h1,3-4,7,10,23H,2,5-6H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298269
(CHEMBL575397 | N-Hydroxy-5-(3-nitroguanidino)-2-(p...)Show SMILES NC(NCCC[C@H](NS(=O)(=O)c1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C12H18N6O6S/c13-12(15-18(21)22)14-8-4-7-10(11(19)16-20)17-25(23,24)9-5-2-1-3-6-9/h1-3,5-6,10,17,20H,4,7-8H2,(H,16,19)(H3,13,14,15)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298255
(CHEMBL584601 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1cccc(c1)[N+]([O-])=O)C(=O)NO)=N[N+]([O-])=O |r,w:23.24| Show InChI InChI=1S/C13H17N7O7/c14-13(17-20(26)27)15-6-2-5-10(12(22)18-23)16-11(21)8-3-1-4-9(7-8)19(24)25/h1,3-4,7,10,23H,2,5-6H2,(H,16,21)(H,18,22)(H3,14,15,17)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.02E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298270
(CHEMBL575400 | N-Hydroxy-2-(4-methylphenylsulfonam...)Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:18.19| Show InChI InChI=1S/C13H20N6O6S/c1-9-4-6-10(7-5-9)26(24,25)18-11(12(20)17-21)3-2-8-15-13(14)16-19(22)23/h4-7,11,18,21H,2-3,8H2,1H3,(H,17,20)(H3,14,15,16)/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.09E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298250
(2-Chloro-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccccc1Cl)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17ClN6O5/c14-9-5-2-1-4-8(9)11(21)17-10(12(22)19-23)6-3-7-16-13(15)18-20(24)25/h1-2,4-5,10,23H,3,6-7H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298257
(CHEMBL576974 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1cccc(c1)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:18.19| Show InChI InChI=1S/C14H20N6O6/c1-26-10-5-2-4-9(8-10)12(21)17-11(13(22)19-23)6-3-7-16-14(15)18-20(24)25/h2,4-5,8,11,23H,3,6-7H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.51E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM23971
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.62E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298251
(CHEMBL574757 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccccc1I)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17IN6O5/c14-9-5-2-1-4-8(9)11(21)17-10(12(22)19-23)6-3-7-16-13(15)18-20(24)25/h1-2,4-5,10,23H,3,6-7H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.76E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298263
(3,4-Dichloro-N-(1-(hydroxyamino)-5-(3-nitroguanidi...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)NO)=N[N+]([O-])=O |r,w:22.23| Show InChI InChI=1S/C13H16Cl2N6O5/c14-8-4-3-7(6-9(8)15)11(22)18-10(12(23)20-24)2-1-5-17-13(16)19-21(25)26/h3-4,6,10,24H,1-2,5H2,(H,18,22)(H,20,23)(H3,16,17,19)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298254
(3-Chloro-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-...)Show SMILES NC(NCCC[C@H](NC(=O)c1cccc(Cl)c1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17ClN6O5/c14-9-4-1-3-8(7-9)11(21)17-10(12(22)19-23)5-2-6-16-13(15)18-20(24)25/h1,3-4,7,10,23H,2,5-6H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.02E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298260
(CHEMBL575800 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NO)=N[N+]([O-])=O |r,w:23.24| Show InChI InChI=1S/C13H17N7O7/c14-13(17-20(26)27)15-7-1-2-10(12(22)18-23)16-11(21)8-3-5-9(6-4-8)19(24)25/h3-6,10,23H,1-2,7H2,(H,16,21)(H,18,22)(H3,14,15,17)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.04E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298258
(4-Chloro-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Cl)cc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17ClN6O5/c14-9-5-3-8(4-6-9)11(21)17-10(12(22)19-23)2-1-7-16-13(15)18-20(24)25/h3-6,10,23H,1-2,7H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298252
(CHEMBL573130 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES Cc1ccccc1C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:17.18| Show InChI InChI=1S/C14H20N6O5/c1-9-5-2-3-6-10(9)12(21)17-11(13(22)19-23)7-4-8-16-14(15)18-20(24)25/h2-3,5-6,11,23H,4,7-8H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298268
(CHEMBL583183 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1cccs1)C(=O)NO)=N[N+]([O-])=O |r,w:19.20| Show InChI InChI=1S/C11H16N6O5S/c12-11(15-17(21)22)13-5-1-3-7(9(18)16-20)14-10(19)8-4-2-6-23-8/h2,4,6-7,20H,1,3,5H2,(H,14,19)(H,16,18)(H3,12,13,15)/t7-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.26E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298264
(4-Bromo-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-1...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Br)c(c1)[N+]([O-])=O)C(=O)NO)=N[N+]([O-])=O |r,w:24.25| Show InChI InChI=1S/C13H16BrN7O7/c14-8-4-3-7(6-10(8)20(25)26)11(22)17-9(12(23)19-24)2-1-5-16-13(15)18-21(27)28/h3-4,6,9,24H,1-2,5H2,(H,17,22)(H,19,23)(H3,15,16,18)/t9-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.36E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298258
(4-Chloro-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Cl)cc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17ClN6O5/c14-9-5-3-8(4-6-9)11(21)17-10(12(22)19-23)2-1-7-16-13(15)18-20(24)25/h3-6,10,23H,1-2,7H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.38E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298253
(CHEMBL576973 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1ccccc1C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:18.19| Show InChI InChI=1S/C14H20N6O6/c1-26-11-7-3-2-5-9(11)12(21)17-10(13(22)19-23)6-4-8-16-14(15)18-20(24)25/h2-3,5,7,10,23H,4,6,8H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.53E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298267
(CHEMBL574274 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:22.23| Show InChI InChI=1S/C16H24N6O8/c1-28-11-7-9(8-12(29-2)13(11)30-3)14(23)19-10(15(24)21-25)5-4-6-18-16(17)20-22(26)27/h7-8,10,25H,4-6H2,1-3H3,(H,19,23)(H,21,24)(H3,17,18,20)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.71E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298261
(CHEMBL574056 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1ccc(cc1)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:18.19| Show InChI InChI=1S/C14H20N6O6/c1-26-10-6-4-9(5-7-10)12(21)17-11(13(22)19-23)3-2-8-16-14(15)18-20(24)25/h4-7,11,23H,2-3,8H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298247
(CHEMBL573367 | N-Hydroxy-5-(3-nitroguanidino)-2-(3...)Show SMILES NC(NCCC[C@H](NC(=O)CCc1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:22.23| Show InChI InChI=1S/C15H22N6O5/c16-15(19-21(25)26)17-10-4-7-12(14(23)20-24)18-13(22)9-8-11-5-2-1-3-6-11/h1-3,5-6,12,24H,4,7-10H2,(H,18,22)(H,20,23)(H3,16,17,19)/t12-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.32E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298266
(CHEMBL574273 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES COc1ccc(cc1OC)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:20.21| Show InChI InChI=1S/C15H22N6O7/c1-27-11-6-5-9(8-12(11)28-2)13(22)18-10(14(23)20-24)4-3-7-17-15(16)19-21(25)26/h5-6,8,10,24H,3-4,7H2,1-2H3,(H,18,22)(H,20,23)(H3,16,17,19)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.46E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298262
(2,4-Dichloro-N-(1-(hydroxyamino)-5-(3-nitroguanidi...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Cl)cc1Cl)C(=O)NO)=N[N+]([O-])=O |r,w:22.23| Show InChI InChI=1S/C13H16Cl2N6O5/c14-7-3-4-8(9(15)6-7)11(22)18-10(12(23)20-24)2-1-5-17-13(16)19-21(25)26/h3-4,6,10,24H,1-2,5H2,(H,18,22)(H,20,23)(H3,16,17,19)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.49E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298259
(4-Bromo-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-1...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Br)cc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17BrN6O5/c14-9-5-3-8(4-6-9)11(21)17-10(12(22)19-23)2-1-7-16-13(15)18-20(24)25/h3-6,10,23H,1-2,7H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.43E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298259
(4-Bromo-N-(1-(hydroxyamino)-5-(3-nitroguanidino)-1...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccc(Br)cc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C13H17BrN6O5/c14-9-5-3-8(4-6-9)11(21)17-10(12(22)19-23)2-1-7-16-13(15)18-20(24)25/h3-6,10,23H,1-2,7H2,(H,17,21)(H,19,22)(H3,15,16,18)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.84E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298256
(CHEMBL573304 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES Cc1cccc(c1)C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:17.18| Show InChI InChI=1S/C14H20N6O5/c1-9-4-2-5-10(8-9)12(21)17-11(13(22)19-23)6-3-7-16-14(15)18-20(24)25/h2,4-5,8,11,23H,3,6-7H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298249
(CHEMBL583058 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES NC(NCCC[C@H](NC(=O)c1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:20.21| Show InChI InChI=1S/C13H18N6O5/c14-13(17-19(23)24)15-8-4-7-10(12(21)18-22)16-11(20)9-5-2-1-3-6-9/h1-3,5-6,10,22H,4,7-8H2,(H,16,20)(H,18,21)(H3,14,15,17)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.93E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298248
(2-Cinnamamido-N-hydroxy-5-(3-nitroguanidino)pentan...)Show SMILES NC(NCCC[C@H](NC(=O)C=Cc1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:22.23,10.9| Show InChI InChI=1S/C15H20N6O5/c16-15(19-21(25)26)17-10-4-7-12(14(23)20-24)18-13(22)9-8-11-5-2-1-3-6-11/h1-3,5-6,8-9,12,24H,4,7,10H2,(H,18,22)(H,20,23)(H3,16,17,19)/t12-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.01E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298247
(CHEMBL573367 | N-Hydroxy-5-(3-nitroguanidino)-2-(3...)Show SMILES NC(NCCC[C@H](NC(=O)CCc1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:22.23| Show InChI InChI=1S/C15H22N6O5/c16-15(19-21(25)26)17-10-4-7-12(14(23)20-24)18-13(22)9-8-11-5-2-1-3-6-11/h1-3,5-6,12,24H,4,7-10H2,(H,18,22)(H,20,23)(H3,16,17,19)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.64E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50298246
(CHEMBL584358 | N-Hydroxy-5-(3-nitroguanidino)-2-(2...)Show SMILES NC(NCCC[C@H](NC(=O)Cc1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22| Show InChI InChI=1S/C14H20N6O5/c15-14(18-20(24)25)16-8-4-7-11(13(22)19-23)17-12(21)9-10-5-2-1-3-6-10/h1-3,5-6,11,23H,4,7-9H2,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.66E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of aminopeptidase N in pig kidney microsome by spectrophotometry |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50298252
(CHEMBL573130 | N-(1-(Hydroxyamino)-5-(3-nitroguani...)Show SMILES Cc1ccccc1C(=O)N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)NO |r,w:17.18| Show InChI InChI=1S/C14H20N6O5/c1-9-5-2-3-6-10(9)12(21)17-11(13(22)19-23)7-4-8-16-14(15)18-20(24)25/h2-3,5-6,11,23H,4,7-8H2,1H3,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.07E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 |
Bioorg Med Chem 17: 4666-73 (2009)
Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3 |
More data for this
Ligand-Target Pair | |
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