Affinity Data by PubMed id=19457659

PubMed code 19457659

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropy				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Binding affinity to Bordetella/Alcaligenes strain FB188 HDAC by FRET assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293703 (2-ethyl-3-methoxy-6-methyl-5-(11-oxododecyl)cycloh...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropy				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropy				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293704 (1,1,1-trifluoro-7-(1H-naphtho[2,3-d]imidazol-2-yl)...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropy				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293705 (((2R,3S,4S,5R,6S)-6-((2R,3R,4S,5S,6R)-4,5-dihydrox...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Binding affinity to Bordetella/Alcaligenes strain FB188 HDAC by FRET assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293702 (11-(3-pentyloxiran-2-yl)undec-9-ynoic acid \| CHEMB...) Show SMILES CCCCCC1OC1CC#CCCCCCCCC(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Binding affinity to Bordetella/Alcaligenes strain FB188 HDAC by FRET assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50238632 ((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropy				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293705 (((2R,3S,4S,5R,6S)-6-((2R,3R,4S,5S,6R)-4,5-dihydrox...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropy				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293702 (11-(3-pentyloxiran-2-yl)undec-9-ynoic acid \| CHEMB...) Show SMILES CCCCCC1OC1CC#CCCCCCCCC(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropy				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM19410 (CHEMBL27759 \| MS-275 \| US11377423, MS-275 \| US1167...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Displacement of Atto700-HA from Bordetella/Alcaligenes strain FB188 HDAH by fluorescence anisotropy				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human NIH3T3 cells by radiometric histone deacetylation assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of HDAC1 by fluorogenic enzyme assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50238632 ((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human NIH3T3 cells by radiometric histone deacetylation assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19410 (CHEMBL27759 \| MS-275 \| US11377423, MS-275 \| US1167...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of HDAC1 by fluorogenic enzyme assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293703 (2-ethyl-3-methoxy-6-methyl-5-(11-oxododecyl)cycloh...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of Bordetella/Alcaligenes strain FB188 HDAH by fluorogenic enzyme assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293704 (1,1,1-trifluoro-7-(1H-naphtho[2,3-d]imidazol-2-yl)...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of Bordetella/Alcaligenes strain FB188 HDAH by fluorogenic enzyme assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of Bordetella/Alcaligenes strain FB188 HDAH by fluorimetric assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of Bordetella/Alcaligenes strain FB188 HDAH by fluorimetric assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293705 (((2R,3S,4S,5R,6S)-6-((2R,3R,4S,5S,6R)-4,5-dihydrox...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of Bordetella/Alcaligenes strain FB188 HDAH by fluorogenic enzyme assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM50293702 (11-(3-pentyloxiran-2-yl)undec-9-ynoic acid \| CHEMB...) Show SMILES CCCCCC1OC1CC#CCCCCCCCC(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of Bordetella/Alcaligenes strain FB188 HDAH by fluorogenic enzyme assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase-like amidohydrolase (Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)	BDBM19410 (CHEMBL27759 \| MS-275 \| US11377423, MS-275 \| US1167...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.18E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of G£ttingen Curated by ChEMBL					Assay Description Inhibition of Bordetella/Alcaligenes strain FB188 HDAH by fluorogenic enzyme assay				Bioorg Med Chem Lett 19: 3651-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.102 BindingDB Entry DOI: 10.7270/Q24T6JFV
University of G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%