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PubMed code 19500981

Compile data set for download or QSAR
Found 26 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297595
PNG
(2-tert-butyl-1-(cyclopropylmethyl)-5-(2-methoxyeth...)
Show SMILES COCCS(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C17H29N3O3S/c1-17(2,3)16-18-14-12-19(24(21,22)10-9-23-4)8-7-15(14)20(16)11-13-5-6-13/h13H,5-12H2,1-4H3
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n/an/an/an/a 26.7n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297614
PNG
(5-((5-bromo-2-methoxypyridin-3-yl)methyl)-2-tert-b...)
Show SMILES COc1ncc(Br)cc1CN1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C21H29BrN4O/c1-21(2,3)20-24-17-13-25(8-7-18(17)26(20)11-14-5-6-14)12-15-9-16(22)10-23-19(15)27-4/h9-10,14H,5-8,11-13H2,1-4H3
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n/an/an/an/a 295n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50297597
PNG
(4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...)
Show SMILES Cc1noc(C)c1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C19H28N4O3S/c1-12-17(13(2)26-21-12)27(24,25)22-9-8-16-15(11-22)20-18(19(3,4)5)23(16)10-14-6-7-14/h14H,6-11H2,1-5H3
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n/an/an/an/a 7.50E+3n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297593
PNG
(2-tert-butyl-1-(cyclopropylmethyl)-5-(methylsulfon...)
Show SMILES CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(C)(=O)=O
Show InChI InChI=1S/C15H25N3O2S/c1-15(2,3)14-16-12-10-17(21(4,19)20)8-7-13(12)18(14)9-11-5-6-11/h11H,5-10H2,1-4H3
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n/an/an/an/a 403n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297594
PNG
(1-(cyclopropylmethyl)-5-(2-methoxyethylsulfonyl)-2...)
Show SMILES COCCS(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Show InChI InChI=1S/C18H31N3O3S/c1-18(2,3)11-17-19-15-13-20(25(22,23)10-9-24-4)8-7-16(15)21(17)12-14-5-6-14/h14H,5-13H2,1-4H3
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n/an/an/an/a 21.5n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297613
PNG
(CHEMBL561890 | propyl 1-(cyclopropylmethyl)-2-neop...)
Show SMILES CCCOC(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Show InChI InChI=1S/C19H31N3O2/c1-5-10-24-18(23)21-9-8-16-15(13-21)20-17(11-19(2,3)4)22(16)12-14-6-7-14/h14H,5-13H2,1-4H3
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n/an/an/an/a 560n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50297608
PNG
(4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...)
Show SMILES Cc1nocc1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C18H26N4O3S/c1-12-16(11-25-20-12)26(23,24)21-8-7-15-14(10-21)19-17(18(2,3)4)22(15)9-13-5-6-13/h11,13H,5-10H2,1-4H3
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n/an/an/an/a 1.80E+4n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297602
PNG
(5-(benzylsulfonyl)-2-tert-butyl-1-(cyclopropylmeth...)
Show SMILES CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C21H29N3O2S/c1-21(2,3)20-22-18-14-23(12-11-19(18)24(20)13-16-9-10-16)27(25,26)15-17-7-5-4-6-8-17/h4-8,16H,9-15H2,1-3H3
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n/an/an/an/a 21.8n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297603
PNG
(1-(cyclopropylmethyl)-2-neopentyl-5-(pyridin-3-yls...)
Show SMILES CC(C)(C)Cc1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1cccnc1
Show InChI InChI=1S/C20H28N4O2S/c1-20(2,3)11-19-22-17-14-23(27(25,26)16-5-4-9-21-12-16)10-8-18(17)24(19)13-15-6-7-15/h4-5,9,12,15H,6-8,10-11,13-14H2,1-3H3
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n/an/an/an/a 24.5n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297607
PNG
(4-(1-(cyclopropylmethyl)-2-neopentyl-6,7-dihydro-1...)
Show SMILES Cc1nocc1S(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Show InChI InChI=1S/C19H28N4O3S/c1-13-17(12-26-21-13)27(24,25)22-8-7-16-15(11-22)20-18(9-19(2,3)4)23(16)10-14-5-6-14/h12,14H,5-11H2,1-4H3
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n/an/an/an/a 18.5n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297604
PNG
(2-tert-butyl-1-(cyclopropylmethyl)-5-(pyridin-3-yl...)
Show SMILES CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1cccnc1
Show InChI InChI=1S/C19H26N4O2S/c1-19(2,3)18-21-16-13-22(26(24,25)15-5-4-9-20-11-15)10-8-17(16)23(18)12-14-6-7-14/h4-5,9,11,14H,6-8,10,12-13H2,1-3H3
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n/an/an/an/a 14.2n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297601
PNG
(1-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...)
Show SMILES CC(C)(C)C(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C19H31N3O/c1-18(2,3)16-20-14-12-21(17(23)19(4,5)6)10-9-15(14)22(16)11-13-7-8-13/h13H,7-12H2,1-6H3
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n/an/an/an/a 320n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297610
PNG
(2-tert-butyl-1-(cyclopropylmethyl)-N-methyl-N-prop...)
Show SMILES CCCN(C)C(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C19H32N4O/c1-6-10-21(5)18(24)22-11-9-16-15(13-22)20-17(19(2,3)4)23(16)12-14-7-8-14/h14H,6-13H2,1-5H3
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n/an/an/an/a 380n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297612
PNG
(1-(cyclopropylmethyl)-2-neopentyl-5-pentyl-4,5,6,7...)
Show SMILES CCCCCN1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Show InChI InChI=1S/C20H35N3/c1-5-6-7-11-22-12-10-18-17(15-22)21-19(13-20(2,3)4)23(18)14-16-8-9-16/h16H,5-15H2,1-4H3
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n/an/an/an/a 3.00E+3n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50297594
PNG
(1-(cyclopropylmethyl)-5-(2-methoxyethylsulfonyl)-2...)
Show SMILES COCCS(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Show InChI InChI=1S/C18H31N3O3S/c1-18(2,3)11-17-19-15-13-20(25(22,23)10-9-24-4)8-7-16(15)21(17)12-14-5-6-14/h14H,5-13H2,1-4H3
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n/an/an/an/a 1.40E+4n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB1 receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297592
PNG
(1-(cyclopropylmethyl)-5-(methylsulfonyl)-2-neopent...)
Show SMILES CC(C)(C)Cc1nc2CN(CCc2n1CC1CC1)S(C)(=O)=O
Show InChI InChI=1S/C16H27N3O2S/c1-16(2,3)9-15-17-13-11-18(22(4,20)21)8-7-14(13)19(15)10-12-5-6-12/h12H,5-11H2,1-4H3
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n/an/an/an/a 439n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297611
PNG
(2-tert-butyl-1-(cyclopropylmethyl)-5-pentyl-4,5,6,...)
Show SMILES CCCCCN1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C19H33N3/c1-5-6-7-11-21-12-10-17-16(14-21)20-18(19(2,3)4)22(17)13-15-8-9-15/h15H,5-14H2,1-4H3
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n/an/an/an/a 878n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297596
PNG
(5-(benzylsulfonyl)-1-(cyclopropylmethyl)-2-neopent...)
Show SMILES CC(C)(C)Cc1nc2CN(CCc2n1CC1CC1)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C22H31N3O2S/c1-22(2,3)13-21-23-19-15-24(12-11-20(19)25(21)14-17-9-10-17)28(26,27)16-18-7-5-4-6-8-18/h4-8,17H,9-16H2,1-3H3
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n/an/an/an/a 13.4n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297597
PNG
(4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...)
Show SMILES Cc1noc(C)c1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C19H28N4O3S/c1-12-17(13(2)26-21-12)27(24,25)22-9-8-16-15(11-22)20-18(19(3,4)5)23(16)10-14-6-7-14/h14H,6-11H2,1-5H3
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n/an/an/an/a 5.10n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297608
PNG
(4-(2-tert-butyl-1-(cyclopropylmethyl)-6,7-dihydro-...)
Show SMILES Cc1nocc1S(=O)(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C18H26N4O3S/c1-12-16(11-25-20-12)26(23,24)21-8-7-15-14(10-21)19-17(18(2,3)4)22(15)9-13-5-6-13/h11,13H,5-10H2,1-4H3
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n/an/an/an/a 55.4n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297598
PNG
(1-(1-(cyclopropylmethyl)-2-neopentyl-6,7-dihydro-1...)
Show SMILES CCCCC(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Show InChI InChI=1S/C20H33N3O/c1-5-6-7-19(24)22-11-10-17-16(14-22)21-18(12-20(2,3)4)23(17)13-15-8-9-15/h15H,5-14H2,1-4H3
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n/an/an/an/a 1.02E+3n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297599
PNG
(CHEMBL562149 | N-benzyl-2-tert-butyl-1-(cyclopropy...)
Show SMILES CN(Cc1ccccc1)C(=O)N1CCc2c(C1)nc(n2CC1CC1)C(C)(C)C
Show InChI InChI=1S/C23H32N4O/c1-23(2,3)21-24-19-16-26(13-12-20(19)27(21)15-18-10-11-18)22(28)25(4)14-17-8-6-5-7-9-17/h5-9,18H,10-16H2,1-4H3
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n/an/an/an/a 637n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297600
PNG
(CHEMBL564065 | N-benzyl-1-(cyclopropylmethyl)-N-me...)
Show SMILES CN(Cc1ccccc1)C(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Show InChI InChI=1S/C24H34N4O/c1-24(2,3)14-22-25-20-17-27(13-12-21(20)28(22)16-19-10-11-19)23(29)26(4)15-18-8-6-5-7-9-18/h5-9,19H,10-17H2,1-4H3
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n/an/an/an/a 523n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297605
PNG
(1-(cyclopropylmethyl)-2-neopentyl-5-(phenylsulfony...)
Show SMILES CC(C)(C)Cc1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C21H29N3O2S/c1-21(2,3)13-20-22-18-15-23(27(25,26)17-7-5-4-6-8-17)12-11-19(18)24(20)14-16-9-10-16/h4-8,16H,9-15H2,1-3H3
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n/an/an/an/a 9.10n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297609
PNG
(4-(1-(cyclopropylmethyl)-2-neopentyl-6,7-dihydro-1...)
Show SMILES Cc1noc(C)c1S(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Show InChI InChI=1S/C20H30N4O3S/c1-13-19(14(2)27-22-13)28(25,26)23-9-8-17-16(12-23)21-18(10-20(3,4)5)24(17)11-15-6-7-15/h15H,6-12H2,1-5H3
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n/an/an/an/a 7n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50297606
PNG
(2-tert-butyl-1-(cyclopropylmethyl)-5-(phenylsulfon...)
Show SMILES CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H27N3O2S/c1-20(2,3)19-21-17-14-22(26(24,25)16-7-5-4-6-8-16)12-11-18(17)23(19)13-15-9-10-15/h4-8,15H,9-14H2,1-3H3
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n/an/an/an/a 7.90n/an/an/an/a



Pfizer Discovery Chemistry

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO cells assessed as inhibition forskolin-induced cAMP release


Bioorg Med Chem Lett 19: 4406-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.062
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%