Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50296484
((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]SR141716A from human CB1 receptor |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50296484
((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m0/s1 | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
| Article
PubMed
| 7.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50296485
((R)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m1/s1 | PDB
Reactome pathway
KEGG
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PC sid
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| 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from human CB2 receptor |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM26740
(N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carbo...)Show InChI InChI=1S/C22H23N3O/c26-22(24-20-7-2-1-3-8-20)25-12-10-17(11-13-25)14-18-15-19-6-4-5-9-21(19)23-16-18/h1-9,15-17H,10-14H2,(H,24,26) | PDB
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| n/a | n/a | 16.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of FAAH |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM26739
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24) | PDB
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| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM26741
(N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carbo...)Show InChI InChI=1S/C21H22N4O/c26-21(23-18-7-2-1-3-8-18)25-14-12-24(13-15-25)16-19-11-10-17-6-4-5-9-20(17)22-19/h1-11H,12-16H2,(H,23,26) | PDB
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| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of FAAH |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50244718
(CHEMBL460273 | JNJ-1661010 | N-phenyl-4-(3-phenyl-...)Show InChI InChI=1S/C19H19N5OS/c25-18(20-16-9-5-2-6-10-16)23-11-13-24(14-12-23)19-21-17(22-26-19)15-7-3-1-4-8-15/h1-10H,11-14H2,(H,20,25) | PDB
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| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of FAAH |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM26739
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24) | PDB
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| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM26739
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24) | PDB
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| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50296484
((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m0/s1 | PDB
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| CHEMBL
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| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM26739
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24) | PDB
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| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of FAAH |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM23120
(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...)Show InChI InChI=1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2 | PDB
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| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM23120
(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...)Show InChI InChI=1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2 | PDB
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| n/a | n/a | 119 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50296484
((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m0/s1 | PDB
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| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50296484
((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m0/s1 | PDB
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| n/a | n/a | 188 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM23120
(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...)Show InChI InChI=1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2 | PDB
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| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of FAAH |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50296484
((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m0/s1 | PDB
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| n/a | n/a | 291 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM23120
(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...)Show InChI InChI=1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2 | PDB
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| n/a | n/a | 306 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50296484
((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m0/s1 | PDB
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| n/a | n/a | 531 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50296484
((S)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50296485
((R)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50296485
((R)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50296485
((R)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50296485
((R)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)Show SMILES Clc1ccc(cc1)[C@@H](OC1CN(C1)C(=O)N1CCCCC1)c1cccnc1Cl |r| Show InChI InChI=1S/C21H23Cl2N3O2/c22-16-8-6-15(7-9-16)19(18-5-4-10-24-20(18)23)28-17-13-26(14-17)21(27)25-11-2-1-3-12-25/h4-10,17,19H,1-3,11-14H2/t19-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide |
Bioorg Med Chem Lett 19: 4241-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.097
BindingDB Entry DOI: 10.7270/Q28S4PZC |
More data for this
Ligand-Target Pair | |
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